Search Results - "O'Neal, Seth E"
-
1
CystiHuman: A model of human neurocysticercosis
Published in PLoS computational biology (01-05-2022)“…The Taenia solium tapeworm is responsible for cysticercosis, a neglected tropical disease presenting as larvae in the body of a host following taenia egg…”
Get full text
Journal Article -
2
Non-local validated parametrization of an agent-based model of local-scale Taenia solium transmission in North-West Peru
Published in PloS one (27-09-2022)“…The pork tapeworm, Taenia solium, is the cause of a preventable zoonotic disease, cysticercosis, affecting both pigs and humans. Continued endemic transmission…”
Get full text
Journal Article -
3
Frequency and Determinant Factors for Calcification in Neurocysticercosis
Published in Clinical infectious diseases (02-11-2021)“…Abstract Background Neurocysticercosis is a major cause of acquired epilepsy. Larval cysts in the human brain eventually resolve and either disappear or leave…”
Get full text
Journal Article -
4
Laboratory Diagnosis of Neurocysticercosis (Taenia solium)
Published in Journal of clinical microbiology (01-09-2018)“…Neurocysticercosis accounts for approximately 30% of all epilepsy cases in most developing countries. The immunodiagnosis of cysticercosis is complex and…”
Get full text
Journal Article -
5
A Rapid Point-of-Care Assay for Cysticercosis Antigen Detection in Urine Samples
Published in The American journal of tropical medicine and hygiene (01-03-2023)“…We report a proof-of-concept study using a dipstick assay to detect Taenia solium antigen in urine samples of 30 patients with subarachnoid neurocysticercosis…”
Get full text
Journal Article -
6
Improved Diagnosis of Viable Parenchymal Neurocysticercosis by Combining Antibody Banding Patterns on Enzyme-Linked Immunoelectrotransfer Blot (EITB) with Antigen Enzyme-Linked Immunosorbent Assay (ELISA)
Published in Journal of clinical microbiology (16-02-2022)“…The diagnosis of neurocysticercosis (NCC) depends on neuroimaging and serological confirmation. While antibody detection by enzyme-linked immunoelectrotransfer…”
Get full text
Journal Article -
7
Development and Laboratory Evaluation of a Simple, Field-Applicable Coproantigen Enzyme-Linked Immunosorbent Assay for Diagnosis of Taeniasis in Northern Peru
Published in Journal of clinical microbiology (20-07-2023)“…Coproantigen detection by enzyme-linked immunosorbent assay (coAg ELISA) is a vital tool for detecting and treating cases of Taenia solium taeniasis. However,…”
Get full text
Journal Article -
8
Spatial relationship between Taenia solium tapeworm carriers and necropsy cyst burden in pigs
Published in PLoS neglected tropical diseases (13-04-2017)“…Taenia solium, a parasite that affects humans and pigs, is the leading cause of preventable epilepsy in the developing world. Geographic hotspots of pigs…”
Get full text
Journal Article -
9
Consistent Measurement of Parasite-Specific Antigen Levels in Sera of Patients with Neurocysticercosis Using Two Different Monoclonal Antibody (mAb)-Based Enzyme-Linked Immunosorbent Assays
Published in Pathogens (Basel) (01-04-2023)“…Monoclonal antibody (mAb)-based enzyme-linked immunosorbent assay (ELISA) is a complementary diagnosis technique for neurocysticercosis (NCC), which detects…”
Get full text
Journal Article -
10
Population Screening for Urine Antigens to Detect Asymptomatic Subarachnoid Neurocysticercosis: A Pilot Study in Northern Peru
Published in The American journal of tropical medicine and hygiene (01-09-2020)“…Subarachnoid neurocysticercosis (SANCC) is a severe and progressive brain infection with . We performed a pilot study of noninvasive screening for SANCC in two…”
Get full text
Journal Article -
11
High Prevalence of Asymptomatic Neurocysticercosis in an Endemic Rural Community in Peru
Published in PLoS neglected tropical diseases (19-12-2016)“…Neurocysticercosis is a common helminthic infection of the central nervous system and an important cause of adult-onset epilepsy in endemic countries. However,…”
Get full text
Journal Article -
12
Porcine model of neurocysticercosis by intracarotid injection of Taenia solium oncospheres: Dose assessment, infection outcomes and serological responses
Published in PLoS neglected tropical diseases (02-06-2022)“…Neurocysticercosis (NCC) is the infection of the human central nervous system (CNS) by Taenia solium larvae that cause significant neurological morbidity…”
Get full text
Journal Article -
13
Barriers to Participation in a Community-Based Program to Control Transmission of Taenia solium in Peru
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…Infection of the brain with larvae (neurocysticercosis) is a leading cause of preventable epilepsy worldwide. Effective and sustainable strategies to control…”
Get full text
Journal Article -
14
Feasibility of a point-of-care test based on quantum dots with a mobile phone reader for detection of antibody responses
Published in PLoS neglected tropical diseases (01-10-2019)“…We developed a novel and portable fluorescent sensor that integrates a lateral flow assay with a quantum dot (Qdots) label and a mobile phone reader for…”
Get full text
Journal Article -
15
Evaluating Urban Taeniasis as a Threat to Cysticercosis Elimination in Northern Peru
Published in The American journal of tropical medicine and hygiene (01-01-2019)“…Reintroduction of into a region in Peru where it had been eliminated prompted evaluation of the possibility of reintroduction from an urban reservoir of…”
Get full text
Journal Article -
16
Neurocysticercosis among People Living Near Pigs Heavily Infected with Cysticercosis in Rural Endemic Peru
Published in The American journal of tropical medicine and hygiene (01-01-2018)“…Neurocysticercosis causes substantial neurologic morbidity in endemic regions around the world. In this cross-sectional study, we describe the frequency of…”
Get full text
Journal Article -
17
Neurocysticercosis: neglected but not forgotten
Published in PLoS neglected tropical diseases (01-05-2012)Get full text
Journal Article -
18
Clustering of Necropsy-Confirmed Porcine Cysticercosis Surrounding Taenia solium Tapeworm Carriers in Peru
Published in The American journal of tropical medicine and hygiene (01-01-2019)“…The pork tapeworm, , is among the leading causes of preventable epilepsy in the world and is common in rural areas of developing countries where sanitation is…”
Get full text
Journal Article -
19
GPS Tracking of Free-Ranging Pigs to Evaluate Ring Strategies for the Control of Cysticercosis/Taeniasis in Peru
Published in PLoS neglected tropical diseases (01-04-2016)“…Taenia solium, a parasitic cestode that affects humans and pigs, is the leading cause of preventable epilepsy in the developing world. T. solium eggs are…”
Get full text
Journal Article -
20
Porcine Cysticercosis: Possible Cross-Reactivity of Taenia hydatigena to GP50 Antigen in the Enzyme-Linked Immunoelectrotransfer Blot Assay
Published in The American journal of tropical medicine and hygiene (01-12-2017)“…The lentil lectin glycoprotein enzyme-linked immunoelectrotransfer blot (LLGP EITB, reported sensitivity 99% and specificity 100%) is used as a serologic…”
Get full text
Journal Article