Search Results - "O'Neal, D. Patrick"
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Layer-by-Layer-Coated Gelatin Nanoparticles as a Vehicle for Delivery of Natural Polyphenols
Published in ACS nano (28-07-2009)“…Natural polyphenols with previously demonstrated anticancer potential, epigallocatechin gallate (EGCG), tannic acid, curcumin, and theaflavin, were encased…”
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Simulation of transport and extravasation of nanoparticles in tumors which exhibit enhanced permeability and retention effect
Published in Computer methods and programs in biomedicine (01-10-2013)“…Abstract Determining the factors that influence the delivery of sub-micron particles to tumors and understanding the relative importance of each of these…”
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Near infrared laser-tissue welding using nanoshells as an exogenous absorber
Published in Lasers in surgery and medicine (01-08-2005)“…Background and Objective Gold nanoshells are a new class of nanoparticles that can be designed to strongly absorb light in the near infrared (NIR). These…”
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Three-wavelength murine photoplethysmography for estimation of vascular gold nanorod concentration
Published in Optics express (06-12-2010)“…Nanoparticle-assisted photo-thermal (NAPT) ablation has become a new and attractive modality for the treatment of cancerous tumors. This therapy exploits the…”
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Quantitative comparison of delta P1 versus optical diffusion approximations for modeling near-infrared gold nanoshell heating
Published in Medical physics (Lancaster) (01-04-2009)“…Laser induced thermal therapy combined with the wavelength dependent optical absorption and heating power of gold-coated silica nanoshells can achieve…”
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Quantitative estimation of gold nanoshell concentrations in whole blood using dynamic light scattering
Published in Nanomedicine (01-03-2007)“…Abstract We demonstrate a new nondestructive optical assay to estimate submicron solid particle concentrations in whole blood. We use dynamic light scattering…”
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Closed-Loop Intravenous Drug Administration Using Photoplethysmography
Published in IEEE journal of translational engineering in health and medicine (01-01-2018)“…An optically-based injection control system has been developed for preclinical use for an intravenous drug delivery application. Current clinical drug delivery…”
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Murine photoplethysmography for in vivo estimation of vascular gold nanoshell concentration
Published in Journal of Biomedical Optics (01-07-2010)“…There is an urgent clinical need to monitor the intravenous delivery and bioavailability of circulating nanoparticles used in cancer therapy. This work…”
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Feasibility study using surface-enhanced Raman spectroscopy for the quantitative detection of excitatory amino acids
Published in Journal of biomedical optics (01-01-2003)“…The release of excitatory amino acids (EAAs) from injured neurons has been associated with secondary injury following head trauma. The development of a rapid…”
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Photo-thermal tumor ablation in mice using near infrared-absorbing nanoparticles
Published in Cancer letters (25-06-2004)“…The following study examines the feasibility of nanoshell-assisted photo-thermal therapy (NAPT). This technique takes advantage of the strong near infrared…”
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Photoacoustic Tomography of a Nanoshell Contrast Agent in the in Vivo Rat Brain
Published in Nano letters (01-09-2004)“…This study demonstrates the feasibility of using nanoshells in vivo as a new contrast-enhancing agent for photoacoustic tomography. Deep penetrating…”
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Feasibility of using a two-wavelength photometer to estimate the concentration of circulating near-infrared extinguishing nanoparticles
Published in Journal of biomedical nanotechnology (01-02-2010)“…We demonstrate a photometer based on pulse oximeter technology designed to test the feasibility of using non-invasive optics to quantify in vivo circulation…”
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Oxygen sensor based on the fluorescence quenching of a ruthenium complex immobilized in a biocompatible Poly(Ethylene glycol) hydrogel
Published in IEEE sensors journal (01-12-2004)“…An optically based system has been developed for use as an oxygen sensor for a cell culture bioreactor. Electrochemical sensors based on the Clark oxygen…”
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LQR tracking of a delay differential equation model for the study of nanoparticle dosing strategies for cancer therapy
Published in 2013 American Control Conference (01-06-2013)“…Currently, the most commonly used treatments for cancerous tumors (chemotherapy, radiation, etc.) have almost no method of monitoring the administration of the…”
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Conference Proceeding -
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Academic-community partnerships for sustainable preparedness and response systems
Published in American journal of disaster medicine (2014)“…Academic institutions possess tremendous resources that could be important for community disaster response and preparedness activities. In-depth exploration of…”
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