Search Results - "O'Mara, Shaun"

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    Preparation, DNA binding, and in vitro cytotoxicity of a pair of enantiomeric platinum(II) complexes, [(R)- and (S)-3-aminohexahydroazepine]dichloroplatinum(II). Crystal structure of the S enantiomer by FENTON, R. R, EASDALE, W. J, ER, H. M, O'MARA, S. M, MCKEAGE, M. J, RUSSELL, P. J, HAMBLEY, T. W

    Published in Journal of medicinal chemistry (28-03-1997)
    “…A pair of enantiomeric Pt(II) complexes, [Pt(R-ahaz)Cl2] and [Pt(S-ahaz)Cl2] (ahaz = 3-aminohexahydroazepine), has been investigated for their ability to bind…”
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    Increased targeting of adenine-rich sequences by (2-amino-2-methyl-3-butanone oxime)dichloroplatinum(II) and investigations into its low cytotoxicity by Hambley, T W, Ling, E C, O'Mara, S, McKeage, M J, Russell, P J

    Published in Journal of biological inorganic chemistry (01-12-2000)
    “…Using assays based on the inhibition of restriction enzyme cleavage of plasmid and synthetic DNA, the complex (2-amino-2-methyl-3-butanone…”
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    Preparation, characterization, cytotoxicity, and mutagenicity of a pair of enantiomeric platinum(II) complexes with the potential to bind enantioselectively to DNA by Vickery, Kymberley, Bonin, Antonio M, Fenton, Ronald R, O'Mara, Shaun, Russell, Pamela J, Webster, Lorraine K, Hambley, Trevor W

    Published in Journal of medicinal chemistry (12-11-1993)
    “…The synthesis of a pair of enantiomeric Pt(II) complexes, [Pt(R,R-eap)Cl2] and [Pt(S,S-eap)Cl2] (eap = N,N-diethyl-2,4-pentanediamine), designed to bind…”
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    c-fms point mutations in acute myeloid leukemia: fact or fiction? by Springall, F, O'Mara, S, Shounan, Y, Todd, A, Ford, D, Iland, H

    Published in Leukemia (01-07-1993)
    “…Point mutations in codons 12, 13, and 61 of N-ras have consistently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) using a…”
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    Heterogeneity of in vitro radiosensitivity in human bladder cancer cells by Barnetson, A R, Banasiak, D, Fisher, R J, Mameghan, H, Ribeiro, J C, Brown, K, Brown, J L, O'Mara, S M, Russell, P J

    Published in Radiation oncology investigations (1999)
    “…Human bladder cancer is often heterogeneous containing biologically different populations. Radiotherapy plus chemotherapy is the most common treatment for…”
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    Analysis of expressed N-ras mutations in human melanoma short-term cell lines with allele specific restriction analysis induced by the polymerase chain reaction by O'Mara, S M, Todd, A V, Russell, P J

    Published in European journal of cancer (1990) (1992)
    “…Mutations in ras genes have been found in the DNA of numerous cancer types including melanomas, but the expression of these mutations in melanomas has not yet…”
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