Search Results - "O'Malley, Katherine J"

No evidence for enhanced disease with human polyclonal SARS-CoV-2 antibody in the ferret model by Reed, Douglas S, McElroy, Anita K, Barbeau, Dominique J, McMillen, Cynthia M, Tilston-Lunel, Natasha L, Nambulli, Shamkumar, Cottle, Emily, Gilliland, Theron C, Rannulu, Hasala, Lundy, Jeneveve, Olsen, Emily L, O'Malley, Katherine J, Xia, Mengying, Hartman, Amy L, Luke, Thomas C, Egland, Kristi, Bausch, Christoph, Wu, Hua, Sullivan, Eddie J, Klimstra, William B, Duprex, W Paul

“…Since SARS-CoV-2 emerged in late 2019, it spread from China to the rest of the world. An initial concern was the potential for vaccine- or antibody-dependent…”
Get full text

Applications of minimally invasive multimodal telemetry for continuous monitoring of brain function and intracranial pressure in macaques with acute viral encephalitis by Ma, Henry, Lundy, Jeneveve D, Cottle, Emily L, O'Malley, Katherine J, Trichel, Anita M, Klimstra, William B, Hartman, Amy L, Reed, Douglas S, Teichert, Tobias, Martin, Negin P

“…Alphaviruses such as Venezuelan equine encephalitis virus (VEEV) and Eastern equine encephalitis virus (EEEV) are arboviruses that can cause severe zoonotic…”
Get full text

A Vibrating Mesh Nebulizer as an Alternative to the Collison Three-Jet Nebulizer for Infectious Disease Aerobiology by Bowling, Jennifer D, O'Malley, Katherine J, Klimstra, William B, Hartman, Amy L, Reed, Douglas S

“…Experimental infection of animals with aerosols containing pathogenic agents is essential for an understanding of the natural history and pathogenesis of…”
Get full text

Long-term persistence of viral RNA and inflammation in the CNS of macaques exposed to aerosolized Venezuelan equine encephalitis virus by Ma, Henry, Albe, Joseph R, Gilliland, Theron, McMillen, Cynthia M, Gardner, Christina L, Boyles, Devin A, Cottle, Emily L, Dunn, Matthew D, Lundy, Jeneveve D, Salama, Noah, O'Malley, Katherine J, Pandrea, Ivona, Teichert, Tobias, Barrick, Stacey, Klimstra, William B, Hartman, Amy L, Reed, Douglas S

“…Venezuelan equine encephalitis virus (VEEV) is a positively-stranded RNA arbovirus of the genus Alphavirus that causes encephalitis in humans. Cynomolgus…”
Get full text

Aerosol prime-boost vaccination provides strong protection in outbred rabbits against virulent type A Francisella tularensis by O'Malley, Katherine J, Bowling, Jennifer D, Stinson, Elizabeth, Cole, Kelly S, Mann, Barbara J, Namjoshi, Prachi, Hazlett, Karsten R O, Barry, Eileen M, Reed, Douglas S

“…Tularemia, also known as rabbit fever, is a severe zoonotic disease in humans caused by the gram-negative bacterium Francisella tularensis (Ft). While there…”
Get full text

Development of Rift valley fever encephalitis in rats is mediated by early infection of olfactory epithelium and neuroinvasion across the cribriform plate by Boyles, Devin A, Schwarz, Madeline M, Albe, Joseph R, McMillen, Cynthia M, O'Malley, Katherine J, Reed, Douglas S, Hartman, Amy L

“…The zoonotic emerging Rift Valley fever virus (RVFV) causes sporadic disease in livestock and humans throughout Africa and the Saudi Arabian peninsula…”
Get full text

Physiological and immunological changes in the brain associated with lethal eastern equine encephalitis virus in macaques by Albe, Joseph R, Ma, Henry, Gilliland, Theron H, McMillen, Cynthia M, Gardner, Christina L, Boyles, Devin A, Cottle, Emily L, Dunn, Matthew D, Lundy, Jeneveve D, O'Malley, Katherine J, Salama, Noah, Walters, Aaron W, Pandrea, Ivona, Teichert, Tobias, Klimstra, William B, Reed, Douglas S, Hartman, Amy L

“…Aerosol exposure to eastern equine encephalitis virus (EEEV) can trigger a lethal viral encephalitis in cynomolgus macaques which resembles severe human…”
Get full text

Development, Characterization, and Standardization of a Nose-Only Inhalation Exposure System for Exposure of Rabbits to Small-Particle Aerosols Containing Francisella tularensis by O'Malley, Katherine J, Bowling, Jennifer D, Barry, Eileen M, Hazlett, Karsten R O, Reed, Douglas S

“…Inhalation of causes pneumonic tularemia in humans, a severe disease with a 30 to 60% mortality rate. The reproducible delivery of aerosolized virulent…”
Get full text

Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques by Wonderlich, Elizabeth R, Swan, Zachary D, Bissel, Stephanie J, Hartman, Amy L, Carney, Jonathan P, O'Malley, Katherine J, Obadan, Adebimpe O, Santos, Jefferson, Walker, Reagan, Sturgeon, Timothy J, Frye, Jr, Lonnie J, Maiello, Pauline, Scanga, Charles A, Bowling, Jennifer D, Bouwer, Anthea L, Duangkhae, Parichat A, Wiley, Clayton A, Flynn, JoAnne L, Wang, Jieru, Cole, Kelly S, Perez, Daniel R, Reed, Douglas S, Barratt-Boyes, Simon M

“…Human infections with highly pathogenic avian influenza A (H5N1) virus are frequently fatal but the mechanisms of disease remain ill-defined. H5N1 infection is…”
Get full text

Upregulation of androgen-responsive genes and transforming growth factor-β1 cascade genes in a rat model of non-bacterial prostatic inflammation by Funahashi, Yasuhito, O'Malley, Katherine J., Kawamorita, Naoki, Tyagi, Pradeep, DeFranco, Donald B., Takahashi, Ryosuke, Gotoh, Momokazu, Wang, Zhou, Yoshimura, Naoki

“…BACKGROUND Prostatic inflammation is associated with the development of prostatic hyperplasia. We investigated the effects of prostatic inflammation on…”
Get full text

Influence of E. coli-induced prostatic inflammation on expression of androgen-responsive genes and transforming growth factor beta 1 cascade genes in rats by Funahashi, Yasuhito, Wang, Zhou, O'Malley, Katherine J., Tyagi, Pradeep, DeFranco, Donald B., Gingrich, Jeffrey R., Takahashi, Ryosuke, Majima, Tsuyoshi, Gotoh, Momokazu, Yoshimura, Naoki

“…BACKGROUND Prostatic inflammation is reportedly associated with the development of prostatic hyperplasia. We investigated the effects of prostatic inflammation…”
Get full text

Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia by O'Malley, Katherine J., Eisermann, Kurtis, Pascal, Laura E., Parwani, Anil V., Majima, Tsuyoshi, Graham, Lara, Hrebinko, Katherine, Acquafondata, Marie, Stewart, Nicolas A., Nelson, Joel B., Yoshimura, Naoki, Wang, Zhou

“…BACKGROUND Benign prostatic hyperplasia (BPH) is an age‐related disease frequently associated with lower urinary tract symptoms (LUTS) that involves…”
Get full text

Refined semi-lethal aerosol H5N1 influenza model in cynomolgus macaques for evaluation of medical countermeasures by Kanekiyo, Masaru, Gillespie, Rebecca A., Midgett, Morgan, O’Malley, Katherine J., Williams, Connor, Moin, Syed M., Wallace, Megan, Treaster, Luke, Cooper, Kristine, Syeda, Hubza, Kettenburg, Gwenddolen, Rannulu, Hasala, Schmer, Tabitha, Ortiz, Lucia, Da Silva Castanha, Priscila, Corry, Jacqueline, Xia, Mengying, Olsen, Emily, Perez, Daniel, Yun, Gabin, Graham, Barney S., Barratt-Boyes, Simon M., Reed, Douglas S.

“…Highly pathogenic avian influenza A H5N1 viruses cause high mortality in humans and have pandemic potential. Effective vaccines and treatments against this…”
Get full text

Hsp90 inhibitor 17-AAG inhibits progression of LuCaP35 xenograft prostate tumors to castration resistance by O'Malley, Katherine J., Langmann, Gabrielle, Ai, Junkui, Ramos-Garcia, Raquel, Vessella, Robert L., Wang, Zhou

“…BACKGROUND Advanced prostate cancer is currently treated with androgen deprivation therapy (ADT). ADT initially results in tumor regression; however, all…”
Get full text

Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice by Pascal, Laura E, Ai, Junkui, Masoodi, Khalid Z, Wang, Yujuan, Wang, Dan, Eisermann, Kurtis, Rigatti, Lora H, O'Malley, Katherine J, Ma, Hei M, Wang, Xinhui, Dar, Javid A, Parwani, Anil V, Simons, Brian W, Ittman, Michael M, Li, Luyuan, Davies, Benjamin J, Wang, Zhou

“…ELL-associated factor 2 (EAF2) is an androgen-responsive tumor suppressor frequently deleted in advanced prostate cancer that functions as a transcription…”
Get full text

T Cell Ig and Mucin 1 (TIM-1) Is Expressed on in vivo-Activated T Cells and Provides a Costimulatory Signal for T Cell Activation by Anjali J. de Souza, Timothy B. Oriss, Katherine J. O'Malley, Ray, Anuradha, Kane, Lawrence P.

“…Polymorphisms in TIM-1, a member of the T cell Ig and mucin (TIM) domain family, are associated with relative susceptibility to the development of T helper…”
Get full text

Corrigendum to “Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion” [Neoplasia 19 (2017) 207-215] by Qiu, Xiaonan, Pascal, Laura E., Song, Qiong, Zang, Yachen, Ai, Junkui, O'Malley, Katherine J., Nelson, Joel B., Wang, Zhou

Get full text

Digoxin Inhibits Blood Vessel Density and HIF-1a Expression in Castration-Resistant C4-2 Xenograft Prostate Tumors by Gayed, Bishoy A., O'Malley, Katherine J., Pilch, Jan, Wang, Zhou

“…Purpose: Recent studies suggest a potential application for digoxin in the prevention and/or treatment of prostate cancer. However, the effect of digoxin on…”
Get full text

Transforming growth factor beta 1 impairs benign prostatic luminal epithelial cell monolayer barrier function by Li, Feng, Pascal, Laura E, Wang, Ke, Zhou, Yibin, Balasubramani, Goundappa K, O'Malley, Katherine J, Dhir, Rajiv, He, Kai, Stolz, Donna, DeFranco, Donald B, Yoshimura, Naoki, Nelson, Joel B, Chong, Tie, Guo, Peng, He, Dalin, Wang, Zhou

“…Our recent studies identifying the presence of luminal secretory protein PSA in the stroma, decreased E-cadherin expression, and reduced number of tight…”
Get full text

Laser-capture microdissection for analysis of cell type-specific gene expression of muscarinic receptor subtypes in the rat bladder with cyclophosphamide-induced cystitis by Sugino, Yoshio, O’Malley, Katherine J., Wang, Zhou, Tyagi, Pradeep, Birder, Lori A., Ogawa, Osamu, Yoshimura, Naoki

“…Purpose This study examined whether the laser-capture microdissection (LCM) method can achieve separation of urothelial cells from detrusor cells or…”
Get full text