Search Results - "O'Leary, David R."
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Interaction with the CCT chaperonin complex limits APOBEC3A cytidine deaminase cytotoxicity
Published in EMBO reports (06-09-2021)“…The APOBEC3 cytidine deaminases are implicated as the cause of a prevalent somatic mutation pattern found in cancer genomes. The APOBEC3 enzymes act as viral…”
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Storage and mobilization of natural and septic nitrate in thick unsaturated zones, California
Published in Journal of hydrology (Amsterdam) (01-05-2015)“…•Natural and NO3 from septic sources are stored in unsaturated zone in arid areas.•Denitrification in the unsaturated zone is about 5–10%.•Managed aquifer…”
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Journal Article -
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Sources of high-chloride water and managed aquifer recharge in an alluvial aquifer in California, USA
Published in Hydrogeology journal (01-11-2015)“…As a result of pumping in excess of recharge, water levels in alluvial aquifers within the Eastern San Joaquin Groundwater Subbasin, 130 km east of San…”
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The SMC5/6 complex prevents genotoxicity upon APOBEC3A-mediated replication stress
Published in The EMBO journal (01-08-2024)“…Mutational patterns caused by APOBEC3 cytidine deaminase activity are evident throughout human cancer genomes. In particular, the APOBEC3A family member is a…”
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Movement of Water Infiltrated from a Recharge Basin to Wells
Published in Ground water (01-03-2012)“…Local surface water and stormflow were infiltrated intermittently from a 40‐ha basin between September 2003 and September 2007 to determine the feasibility of…”
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The Clonal Hematopoietic Spectrum of Down Syndrome and ML-DS
Published in Blood (29-11-2018)“…Introduction: Children with Down syndrome (DS) have a 150-fold higher risk of developing myeloid leukemia (ML-DS) (Wechsler J, Nat Gen 2002). Ten percent (10%)…”
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