Search Results - "O'Leary, Daniel J."

Z‑Selective Olefin Metathesis on Peptides: Investigation of Side-Chain Influence, Preorganization, and Guidelines in Substrate Selection by Mangold, Shane L, O’Leary, Daniel J, Grubbs, Robert H

“…Olefin metathesis has emerged as a promising strategy for modulating the stability and activity of biologically relevant compounds; however, the ability to…”
Get full text

1H NMR Studies of Intramolecular OH/OH Hydrogen Bonds via Titratable Isotope Shifts by Kolahdouzan, Kavoos, Ogba, O. Maduka, O’Leary, Daniel J

“…Methanol titrations of partially deuterated 1,4- and 1,3-diols dissolved in nonpolar solvents such as CD2Cl2 and benzene-d 6 have provided 1H NMR measurements…”
Get full text

Do-It-Yourself 5‑Color 3D Printing of Molecular Orbitals and Electron Density Surfaces by Garcia, Michelle, O’Leary, Frances A., O’Leary, Daniel J.

“…This report outlines an approach for preparing 5-color 3D printed plastic models of molecular orbitals and electron density surfaces using a hobby-grade 3D…”
Get full text

In Memoriam: The Life and Scientific Accomplishments of Frank A. L. Anet (1926–2024) by Freedberg, Darón I., Hud, Nicholas V., Kopelevich, Max, O'Leary, Daniel J., Strouse, Jane

“…ABSTRACT A memorial tribute detailing the life and scientific accomplishments of Frank A. L. Anet, a pioneer of nuclear magnetic resonance (NMR) spectroscopy…”
Get full text

Undercorrection of myopia enhances rather than inhibits myopia progression by Chung, Kahmeng, Mohidin, Norhani, O’Leary, Daniel J.

“…The effect of myopic defocus on myopia progression was assessed in a two-year prospective study on 94 myopes aged 9{14 years, randomly allocated to an…”
Get full text

The Cambridge Anti-Myopia Study: Variables Associated with Myopia Progression by Price, Holly, Allen, Peter M, Radhakrishnan, Hema, Calver, Richard, Rae, Sheila, Theagarayan, Baskar, Sailoganathan, Ananth, O’Leary, Daniel J

“…PURPOSETo identify variables associated with myopia progression and to identify any interaction between accommodative function, myopia progression, age, and…”
Get full text

1H and 13C NMR Assignments for the Cyanine Dyes SYBR Safe and Thiazole Orange by Evenson, William E, Boden, Lauren M, Muzikar, Katy A, O’Leary, Daniel J

“…Analysis of 1H and 13C NMR and mass spectral data for the fluorescent nucleic acid stain SYBR Safe indicates that it contains a cyanine-based cationic core…”
Get full text

Enantioselective Photocycloaddition Mediated by Chiral Brønsted Acids:  Asymmetric Synthesis of the Rocaglamides by Gerard, Baudouin, Sangji, Sheharbano, O'Leary, Daniel J, Porco, John A

“…Enantioselective syntheses of methyl rocaglate and the related natural products rocaglamide and rocaglaol are outlined. The approach involves enantioselective…”
Get full text

Accommodation functions: Co-dependency and relationship to refractive error by Allen, Peter M., O’Leary, Daniel J.

“…We assessed the extent to which different accommodative functions are correlated and whether accommodative functions predict the refractive error or the…”
Get full text

The Tripeptide RER Mimics Secreted Amyloid Precursor Protein-Alpha in Upregulating LTP by Morrissey, Jodi A., Bigus, Erin, Necarsulmer, Julie C., Srinivasan, Vinay, Peppercorn, Katie, O’Leary, Daniel J., Mockett, Bruce G., Tate, Warren P., Hughes, Stephanie M., Parfitt, Karen D., Abraham, Wickliffe C.

“…Secreted amyloid precursor protein-alpha (sAPPα), generated by enzymatic processing of the amyloid precursor protein, possesses a range of neurotrophic and…”
Get full text

Ruthenium-Olefin Complexes: Effect of Ligand Variation upon Geometry by Anderson, Donde R., O'Leary, Daniel J., Grubbs, Robert H.

“…The development of a model system to study ruthenium–olefin complexes relevant to the mechanism of olefin metathesis has been reported recently. Upon addition…”
Get full text

Facile and E-Selective Intramolecular Ring-Closing Metathesis Reactions in 310-Helical Peptides:  A 3D Structural Study by Boal, Amie K, Guryanov, Ivan, Moretto, Alessandro, Crisma, Marco, Lanni, Erica L, Toniolo, Claudio, Grubbs, Robert H, O'Leary, Daniel J

“…The ring-closing metathesis reaction can be used to cross-link allylated serine residues situated at the i and i + 3 positions in 310-helical peptides…”
Get full text

Enthalpy/entropy contributions to conformational KIEs: theoretical predictions and comparison with experiment by Fong, Aaron, Meyer, Matthew P, O'Leary, Daniel J

“…Previous theoretical studies of Mislow's doubly-bridged biphenyl ketone 1 and dihydrodimethylphenanthrene 2 have determined significant entropic contributions…”
Get full text

Model Compounds of Ruthenium−Alkene Intermediates in Olefin Metathesis Reactions by Anderson, Donde R, Hickstein, Daniel D, O'Leary, Daniel J, Grubbs, Robert H

“…The development of a model system to study ruthenium−olefin complexes relevant to the mechanism of olefin metathesis is reported. Upon addition of…”
Get full text

1 H NMR Studies of Intramolecular OH/OH Hydrogen Bonds via Titratable Isotope Shifts by Kolahdouzan, Kavoos, Ogba, O Maduka, O'Leary, Daniel J

“…Methanol titrations of partially deuterated 1,4- and 1,3-diols dissolved in nonpolar solvents such as CD Cl and benzene- have provided H NMR measurements of…”
Get full text

Ring-Closing Metathesis of Olefinic Peptides:  Design, Synthesis, and Structural Characterization of Macrocyclic Helical Peptides by Blackwell, Helen E, Sadowsky, Jack D, Howard, Rebecca J, Sampson, Joshua N, Chao, Jeffery A, Steinmetz, Wayne E, O'Leary, Daniel J, Grubbs, Robert H

“…Heptapeptides containing residues with terminal olefin-derivatized side chains (3 and 4) have been treated with ruthenium alkylidene 1 and undergone facile…”
Get full text

Repeatability and validity of the PowerRefractor and the Nidek AR600-A in an adult population with healthy eyes by ALLEN, Peter M, RADHAKRISHNAN, Hema, O'LEARY, Daniel J

“…We assessed the repeatability and validity of the PowerRefractor and the Nidek AR-600A autorefractor. This is the first independent study conducted on adults…”
Get full text

Structure-Selectivity Relationships and Structure for a Peptide-Based Enantioselective Acylation Catalyst by Fierman, Matthew B, O'Leary, Daniel J, Steinmetz, Wayne E, Miller, Scott J

“…Studies of analogues of a recently discovered enantioselective peptide-based catalyst for enantioselective acylation reactions have led to mechanistic insight…”
Get full text

Following Molecular Mobility during Chemical Reactions: No Evidence for Active Propulsion by Fillbrook, Lucy L, Günther, Jan-Philipp, Majer, Günter, O’Leary, Daniel J, Price, William S, Van Ryswyk, Hal, Fischer, Peer, Beves, Jonathon E

“…The reported changes in self-diffusion of small molecules during reactions have been attributed to “boosted mobility”. We demonstrate the critical role of…”
Get full text

The effect of altering spherical aberration on the static accommodative response by Theagarayan, Baskar, Radhakrishnan, Hema, Allen, Peter M., Calver, Richard I., Rae, Sheila M., O'Leary, Daniel J.

“…Purpose:  To investigate the effect of altering the spherical aberration (SA) of the eye on the static accommodative response. Methods:  Participants were…”
Get full text