Search Results - "O'Leary, Caroline A"
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Expression profiling feline peripheral blood monocytes identifies a transcriptional signature associated with type two diabetes mellitus
Published in Veterinary immunology and immunopathology (01-04-2017)“…•Feline blood monocytes specifically resemble human monocytes at a transcriptional level.•Monocytes from cats with T2D exhibit a distinct expression profile to…”
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A KCNJ10 mutation previously identified in the Russell group of terriers also occurs in Smooth-Haired Fox Terriers with hereditary ataxia and in related breeds
Published in Acta veterinaria scandinavica (23-05-2015)“…Hereditary ataxias with similar phenotypes were reported in the Smooth-Haired Fox Terrier, the Jack Russell Terrier and the Parson Russell Terrier. However,…”
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High-throughput lectin magnetic bead array-coupled tandem mass spectrometry for glycoprotein biomarker discovery
Published in Electrophoresis (01-12-2011)“…Alterations in protein glycosylation occur during development and progression of many diseases, hence glycomics and glycoproteomics have emerged as important…”
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Atopic dermatitis in West Highland white terriers is associated with a 1.3-Mb region on CFA 17
Published in Immunogenetics (New York) (01-03-2012)“…Canine atopic dermatitis (AD) is an allergic inflammatory skin disease that shares similarities with AD in humans. Canine AD is likely to be an inherited…”
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Prevalence of congenital hereditary sensorineural deafness in Australian Cattle Dogs and associations with coat characteristics and sex
Published in BMC veterinary research (29-10-2012)“…Congenital hereditary sensorineural deafness (CHSD) occurs in many dog breeds, including Australian Cattle Dogs. In some breeds, CHSD is associated with a lack…”
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A non-synonymous mutation in the canine Pkd1 gene is associated with autosomal dominant polycystic kidney disease in Bull Terriers
Published in PloS one (27-07-2011)“…Polycystic Kidney Disease is an autosomal dominant disease common in some lines of Bull Terriers (BTPKD). The disease is linked to the canine orthologue of…”
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Congenital sensorineural deafness in Australian stumpy-tail cattle dogs is an autosomal recessive trait that maps to CFA10
Published in PloS one (12-10-2010)“…Congenital sensorineural deafness is an inherited condition found in many dog breeds, including Australian Stumpy-tail Cattle Dogs (ASCD). This deafness is…”
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Molecular evidence of Rickettsia felis infection in dogs from Northern Territory, Australia
Published in Parasites & vectors (11-10-2011)“…The prevalence of spotted fever group rickettsial infection in dogs from a remote indigenous community in the Northern Territory (NT) was determined using…”
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High allergen-specific serum immunoglobulin E levels in nonatopic West Highland white terriers
Published in Veterinary dermatology (01-06-2011)“…Human and canine atopic dermatitis (AD) share an association with IgE specific to environmental allergens, but few studies have evaluated serum…”
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Real-time PCR quantification of the canine filaggrin orthologue in the skin of atopic and non-atopic dogs: a pilot study
Published in BMC research notes (21-12-2011)“…Canine atopic dermatitis (AD) is a common inflammatory skin disease associated with defects in the epidermal barrier, particularly in West Highland white…”
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PTPN22 polymorphisms may indicate a role for this gene in atopic dermatitis in West Highland white terriers
Published in BMC research notes (30-12-2011)“…Canine atopic dermatitis is an allergic inflammatory skin disease common in West Highland white terriers. A genome-wide association study for atopic dermatitis…”
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Potential Modifying Loci Associated With Primary Lens Luxation, Pedal Hyperkeratosis, and Ocular Phenotypes in Miniature Bull Terriers
Published in Investigative ophthalmology & visual science (01-12-2015)“…Primary lens luxation (PLL) in dogs is an inherited disease in which the lens is displaced from its normal position. A truncating mutation in the ADAMTS17…”
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An ADAMTS17 splice donor site mutation in dogs with primary lens luxation
Published in Investigative ophthalmology & visual science (01-09-2010)“…To identify the genetic cause of isolated canine ectopia lentis, a well-characterized veterinary disease commonly referred to as primary lens luxation (PLL)…”
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Molecular evidence supports the role of dogs as potential reservoirs for Rickettsia felis
Published in Vector borne and zoonotic diseases (Larchmont, N.Y.) (01-08-2011)“…Rickettsia felis causes flea-borne spotted fever in humans worldwide. The cat flea, Ctenocephalides felis, serves as vector and reservoir host for this disease…”
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15
High allergen-specific serum immunoglobulinE levels in nonatopic West Highland white terriers
Published in Veterinary dermatology (01-06-2011)“…Human and canine atopic dermatitis (AD) share an association with IgE specific to environmental allergens, but few studies have evaluated serum…”
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Abstract 2499: Diagnostic serum biomarkers for canine hemangiosarcoma: a potential model of human angiosarcoma
Published in Cancer research (Chicago, Ill.) (15-04-2013)“…People suffering from uncommon diseases often do not benefit from the advances in medical research due to lack of research. One such disease is angiosarcoma, a…”
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