Search Results - "O'Kelly, Ita M."

Ursodeoxycholic acid inhibits uptake and vasoconstrictor effects of taurocholate in human placenta by Lofthouse, Emma M., Torrens, Christopher, Manousopoulou, Antigoni, Nahar, Monica, Cleal, Jane K., O'Kelly, M. Ita, Sengers, Bram G., Garbis, Spiros D., Lewis, Rohan M.

“…ABSTRACT Intrahepatic cholestasis of pregnancy (ICP) causes increased transfer of maternal bile acids to the fetus and an increased incidence of sudden fetal…”
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Glutamate cycling may drive organic anion transport on the basal membrane of human placental syncytiotrophoblast by Lofthouse, Emma M., Brooks, Suzanne, Cleal, Jane K., Hanson, Mark A., Poore, Kirsten R., O'Kelly, Ita M., Lewis, Rohan M.

“…Key points The placenta removes waste products, drugs and environmental toxins from the fetal circulation and two of the transport proteins responsible for…”
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Protein Kinase A Is Central for Forward Transport of Two-pore Domain Potassium Channels K2P3.1 and K2P9.1 by Mant, Alexandra, Elliott, David, Eyers, Patrick A., O'Kelly, Ita M.

“…Acid-sensitive two-pore domain potassium channels (K2P3.1 and K2P9.1) play key roles in both physiological and pathophysiological mechanisms, the most…”
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Rare Variants in NR2F2 Cause Congenital Heart Defects in Humans by Al Turki, Saeed, Manickaraj, Ashok K., Mercer, Catherine L., Gerety, Sebastian S., Hitz, Marc-Phillip, Lindsay, Sarah, D’Alessandro, Lisa C.A., Swaminathan, G. Jawahar, Bentham, Jamie, Arndt, Anne-Karin, Louw, Jacoba, Breckpot, Jeroen, Gewillig, Marc, Thienpont, Bernard, Abdul-Khaliq, Hashim, Harnack, Christine, Hoff, Kirstin, Kramer, Hans-Heiner, Schubert, Stephan, Siebert, Reiner, Toka, Okan, Cosgrove, Catherine, Watkins, Hugh, Lucassen, Anneke M., O’Kelly, Ita M., Salmon, Anthony P., Bu’Lock, Frances A., Granados-Riveron, Javier, Setchfield, Kerry, Thornborough, Chris, Brook, J. David, Mulder, Barbara, Klaassen, Sabine, Bhattacharya, Shoumo, Devriendt, Koen, FitzPatrick, David R., Wilson, David I., Mital, Seema, Hurles, Matthew E.

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Rare Variants in NR2F2 Cause Congenital Heart Defects in Humans by Al Turki, Saeed, Manickaraj, Ashok K., Mercer, Catherine L., Gerety, Sebastian S., Hitz, Marc-Phillip, Lindsay, Sarah, D’Alessandro, Lisa C.A., Swaminathan, G. Jawahar, Bentham, Jamie, Arndt, Anne-Karin, Louw, Jacoba, Breckpot, Jeroen, Gewillig, Marc, Thienpont, Bernard, Abdul-Khaliq, Hashim, Harnack, Christine, Hoff, Kirstin, Kramer, Hans-Heiner, Schubert, Stephan, Siebert, Reiner, Toka, Okan, Cosgrove, Catherine, Watkins, Hugh, Lucassen, Anneke M., O’Kelly, Ita M., Salmon, Anthony P., Bu’Lock, Frances A., Granados-Riveron, Javier, Setchfield, Kerry, Thornborough, Chris, Brook, J. David, Mulder, Barbara, Klaassen, Sabine, Bhattacharya, Shoumo, Devriendt, Koen, FitzPatrick, David R., Wilson, David I., Mital, Seema, Hurles, Matthew E.

“…Congenital heart defects (CHDs) are the most common birth defect worldwide and are a leading cause of neonatal mortality. Nonsyndromic atrioventricular septal…”
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N-acetylcysteine, xCT and suppression of Maxi-chloride channel activity in human placenta by Lofthouse, Emma M., Manousopoulou, Antigoni, Cleal, Jane K., O'Kelly, Ita M., Poore, Kirsten R., Garbis, Spiros D., Lewis, Rohan M.

“…Placental oxidative stress features in pregnancy pathologies but in clinical trials antioxidant supplementation has not improved outcomes. N-acetylcysteine…”
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Estrone sulphate uptake by the microvillous membrane of placental syncytiotrophoblast is coupled to glutamate efflux by Lofthouse, Emma M., Cleal, Jane K., O'Kelly, Ita M., Sengers, Bram G., Lewis, Rohan M.

“…Organic anion transporters (OATs) and organic anion transporting polypeptides (OATPs) are transport proteins that mediate exchange of metabolites, hormones and…”
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Acute hypoxic regulation of recombinant THIK-1 stably expressed in HEK293 cells by Fearon, Ian M, Campanucci, Veronica A, Brown, Stephen T, Hudasek, Kristin, O'Kelly, Ita M, Nurse, Colin A

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Rare Variants in NR2F2 Cause Congenital Heart Defects in Humans by Al Turki, Saeed, Manickaraj, Ashok K., Mercer, Catherine L., Gerety, Sebastian S., Hitz, Marc-Phillip, Lindsay, Sarah, D’Alessandro, Lisa C.A., Swaminathan, G. Jawahar, Bentham, Jamie, Arndt, Anne-Karin, Low, Jacoba, Breckpot, Jeroen, Gewillig, Marc, Thienpont, Bernard, Abdul-Khaliq, Hashim, Harnack, Christine, Hoff, Kirstin, Kramer, Hans-Heiner, Schubert, Stephan, Siebert, Reiner, Toka, Okan, Cosgrove, Catherine, Watkins, Hugh, Lucassen, Anneke M., O’Kelly, Ita M., Salmon, Anthony P., Bu’Lock, Frances A., Granados-Riveron, Javier, Setchfield, Kerry, Thornborough, Chris, Brook, J. David, Mulder, Barbara, Klaassen, Sabine, Bhattacharya, Shoumo, Devriendt, Koen, FitzPatrick, David R., Wilson, David I., Mital, Seema, Hurles, Matthew E.

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System-specific O2 sensitivity of the tandem pore domain K+ channel TASK-1 by Johnson, Rosalyn P, O'Kelly, Ita M, Fearon, Ian M

“…Hypoxic inhibition of TASK-1, a tandem pore domain background K+ channel, provides a critical link between reduced O2 levels and physiological responses in…”
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