Search Results - "O'Keefe, L C"

Impact of molecular mutations on treatment response to DNMT inhibitors in myelodysplasia and related neoplasms by Traina, F, Visconte, V, Elson, P, Tabarroki, A, Jankowska, A M, Hasrouni, E, Sugimoto, Y, Szpurka, H, Makishima, H, O'Keefe, C L, Sekeres, M A, Advani, A S, Kalaycio, M, Copelan, E A, Saunthararajah, Y, Olalla Saad, S T, Maciejewski, J P, Tiu, R V

“…We hypothesized that specific molecular mutations are important biomarkers for response to DNA methyltransferase inhibitors (DNMT inhibitors) and may have…”
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Double‐negative regulatory T cells induce allotolerance when expanded after allogeneic haematopoietic stem cell transplantation by McIver, Z., Serio, B., Dunbar, A., O’Keefe, C. L., Powers, J., Wlodarski, M., Jin, T., Sobecks, R., Bolwell, B., Maciejewski, J. P.

“…Summary Double‐negative (DN) regulatory T cells (Tregs) are specialized T lymphocytes involved in the down‐modulation of immune responses, resulting in…”
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Deletions of Xp22.2 including PIG-A locus lead to paroxysmal nocturnal hemoglobinuria by O'Keefe, C L, Sugimori, C, Afable, M, Clemente, M, Shain, K, Araten, D J, List, A, Epling-Burnette, P K, Maciejewski, J P

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Efficacy of rabbit anti-thymocyte globulin in severe aplastic anemia by AFABLE, Manuel G, SHAIK, Mohammed, TIU, Ramon V, O'KEEFE, Christine L, MACIEJEWSKI, Jaroslaw P, SUGIMOTO, Yuka, ELSON, Paul, CLEMENTE, Michael, MAKISHIMA, Hideki, SEKERES, Mikkael A, LICHTIN, Alan, ADVANI, Anjali, KALAYCIO, Matt

“…A combination of horse anti-thymocyte globulin and cyclosporine produces responses in 60-70% of patients with severe aplastic anemia. We performed a phase II…”
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Single nucleotide polymorphism arrays complement metaphase cytogenetics in detection of new chromosomal lesions in MDS by Gondek, L P, Tiu, R, Haddad, A S, O'Keefe, C L, Sekeres, M A, Theil, K S, Maciejewski, J P

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Paroxysmal nocturnal hemoglobinuria and concurrent JAK2(V617F) mutation by Sugimori, C, Padron, E, Caceres, G, Shain, K, Sokol, L, Zhang, L, Tiu, R, O'Keefe, C L, Afable, M, Clemente, M, Lee, J M, Maciejewski, J P, List, A F, Epling-Burnette, P K, Araten, D J

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Molecular cloning of the RNA polymerase I transcription factor hUBF/NOR-90 (UBTF) gene and localization to 17q21.3 by fluorescence in situ hybridization and radiation hybrid mapping by MATERA, A. G, WU, W, IMAI, H, O'KEEFE, C. L, CHAN, E. K. L

“…The 90-kDa nucleolus organizer region autoantigen (NOR-90) was previously shown to be identical to human upstream binding factor (hUBF), which has two…”
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Alphoid variant-specific FISH probes can distinguish autosomal meiosis I from meiosis II non-disjunction in human sperm by O'KEEFE, C. L, GRIFFIN, D. K, BEAN, C. J, MATERA, A. G, HASSOLD, T. J

“…Over the past few years, several groups have used fluorescence in situ hybridization (FISH) to study aneuploidy in human sperm. Several important observations…”
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Oligonucleotide Probes for Alpha Satellite DNA Variants Can Distinguish Homologous Chromosomes by FISH by O'Keefe, Christine L., Warburton, Peter E., Matera, A. Gregory

“…Chromosomal heteromorphisms have been used extensively to mark individual chromosomes. However, classical banding techniques used to identify these structural…”
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Paroxysmal nocturnal hemoglobinuria and concurrent JAK2V617F mutation by Sugimori, C, Padron, E, Caceres, G, Shain, K, Sokol, L, Zhang, L, Tiu, R, O'Keefe, C L, Afable, M, Clemente, M, Lee, J M, Maciejewski, J P, List, A F, Epling-Burnette, P K, Araten, D J

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248 Validating the stage of maturity at harvest for barley, oat, and triticale for swath grazing by O'Keefe, C. L., Larson, K., Penner, G. B., McKinnon, J. J., Lardner, H.

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Validating the stage of maturity at harvest for barley, oat, and triticale for swath grazing by O'Keefe, C L, Larson, K, Penner, G B, McKinnon, J J, Lardner, H

“…An abstract of a study by O Keefe et al determining the effect of harvest maturity (SOM) for barley, oat, and triticale on grazing days, nutrient composition,…”
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Alpha satellite DNA variant-specific oligoprobes differing by a single base can distinguish chromosome 15 homologs by O'Keefe, C L, Matera, A G

“…The ability to distinguish homologous chromosomes is a powerful cytogenetic tool. However, traditional techniques can only distinguish extreme physical…”
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Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4 by Guan, K L, Jenkins, C W, Li, Y, O'Keefe, C L, Noh, S, Wu, X, Zariwala, M, Matera, A G, Xiong, Y

“…Cyclin-dependent kinases 4 and 6 are complexed with many small cellular proteins in vivo. We have isolated cDNA sequences, INK4d, encoding a 19-kDa protein…”
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Autonomy in practice: are nurse practitioner students being prepared for reality? by Black, K A, Dooley, W C, Hersh, S T, O'Keefe, L C, Patrick, L A

“…This article reports on a study examining the relationship between nurse practitioner students' expectations of future professional autonomy and the level of…”
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Molecular Analysis of TCR Clonotypes in LGL: A Clonal Model for Polyclonal Responses by O'Keefe, Christine L, Plasilova, Magdalena, Wlodarski, Marcin, Risitano, Antonio M, Rodriguez, Alexander R, Howe, Evan, Young, Neal S, Hsi, Eric, Maciejewski, Jaroslaw P

“…Large granular lymphocytic (LGL) leukemia is a clonal lymphoproliferative disorder of CTL associated with cytopenias resulting from an immune and cytokine…”
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Detection of mature T-cell leukemias by flow cytometry using anti-T-cell receptor Vβ antibodies by BECK, Rose C, STAHL, Steve, O'KEEFE, Christine L, MACIEJEWSKI, Jaroslaw P, THEIL, Karl S, HSI, Eric D

“…A broad array of antibodies directed against the variable (V) region of the T-cell receptor (TCR) beta (V beta) chain has become available in a directly…”
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Molecular TCR diagnostics can be used to identify shared clonotypes after allogeneic hematopoietic stem cell transplantation by O'Keefe, Christine L., Sobecks, Ronald M., Wlodarski, Mercin, Rodriguez, Alexander, Bell, Kimberly, Kuczkowski, Elizabeth, Bolwell, Brian J., Maciejewski, Jaroslaw P.

“…In allogeneic hematopoietic stem cell (HSCT) transplantation, recovery of the T cell receptor (TCR) repertoire depends upon the composition of the graft and is…”
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Shared and individual specificities of immunodominant cytotoxic T-cell clones in paroxysmal nocturnal hemoglobinuria as determined by molecular analysis by Plasilova, Magdalena, Risitano, Antonio M, O'Keefe, Christine L, Rodriguez, Alexander, Wlodarski, Marcin, Young, Neal S, Maciejewski, Jaroslaw

“…Similar immune mechanisms have been suggested to operate in aplastic anemia (AA) and paroxysmal nocturnal hemoglobinuria (PNH), and the presence of PNH clones…”
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Isolation and characterization of p19INK4d, a p16-related inhibitor specific to CDK6 and CDK4 by Guan, K L, Jenkins, C W, Li, Y, O'Keefe, C L, Noh, S, Wu, X, Zariwala, M, Matera, A G, Xiong, Y

“…Cyclin-dependent kinases 4 and 6 are complexed with many small cellular proteins in vivo. We have isolated cDNA sequences, INK4d, encoding a 19-kDa protein…”
Get full text