Search Results - "O'Hara Hall, Aisling"

The lncRNA LUCAT1 is elevated in inflammatory disease and restrains inflammation by regulating the splicing and stability of NR4A2 by Vierbuchen, Tim, Agarwal, Shiuli, Johnson, John L, Galia, Liraz, Lei, Xuqiu, Stein, Karina, Olagnier, David, Gaede, Karoline I, Herzmann, Christian, Holm, Christian K, Heine, Holger, Pai, Athma, O'Hara Hall, Aisling, Hoebe, Kasper, Fitzgerald, Katherine A

“…The nuclear long non-coding RNA LUCAT1 has previously been identified as a negative feedback regulator of type I interferon and inflammatory cytokine…”
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CD11c-Expressing Cells Affect Regulatory T Cell Behavior in the Meninges during Central Nervous System Infection by O'Brien, Carleigh A, Overall, Christopher, Konradt, Christoph, O'Hara Hall, Aisling C, Hayes, Nikolas W, Wagage, Sagie, John, Beena, Christian, David A, Hunter, Christopher A, Harris, Tajie H

“…Regulatory T cells (Tregs) play an important role in the CNS during multiple infections, as well as autoimmune inflammation, but the behavior of this cell type…”
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The aryl hydrocarbon receptor promotes IL-10 production by NK cells by Wagage, Sagie, John, Beena, Krock, Bryan L, Hall, Aisling O'Hara, Randall, Louise M, Karp, Christopher L, Simon, M Celeste, Hunter, Christopher A

“…The cytokine IL-10 has an important role in limiting inflammation in many settings, including toxoplasmosis. In the present studies, an IL-10 reporter mouse…”
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Get the IL-17F outta here by Hall, Aisling O’Hara, Towne, Jennifer E., Plevy, Scott E.

“…The cytokine IL-17F constrains the growth of immunoregulatory Clostridium cluster XIVa species and represents a potential therapeutic target for the treatment…”
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Cutting edge: suppression of GM-CSF expression in murine and human T cells by IL-27 by Young, Andrew, Linehan, Eimear, Hams, Emily, O'Hara Hall, Aisling C, McClurg, Angela, Johnston, James A, Hunter, Christopher A, Fallon, Padraic G, Fitzgerald, Denise C

“…GM-CSF is a potent proinflammatory cytokine that plays a pathogenic role in the CNS inflammatory disease experimental autoimmune encephalomyelitis. As IL-27…”
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Low-Dose Interleukin-2 Ameliorates Colitis in a Preclinical Humanized Mouse Model by Goettel, Jeremy A, Kotlarz, Daniel, Emani, Rohini, Canavan, James B, Konnikova, Liza, Illig, David, Frei, Sandra M, Field, Michael, Kowalik, Matthew, Peng, Kaiyue, Gringauz, Jordan, Mitsialis, Vanessa, Wall, Sarah M, Tsou, Amy, Griffith, Alexandra E, Huang, Ying, Friedman, Joshua R, Towne, Jennifer E, Plevy, Scott E, O’Hara Hall, Aisling, Snapper, Scott B

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Interleukin-27 Priming of T Cells Controls IL-17 Production In trans via Induction of the Ligand PD-L1 by Hirahara, Kiyoshi, Ghoreschi, Kamran, Yang, Xiang-Ping, Takahashi, Hayato, Laurence, Arian, Vahedi, Golnaz, Sciumè, Giuseppe, Hall, Aisling O'Hara, Dupont, Christopher D., Francisco, Loise M., Chen, Qian, Tanaka, Masao, Kanno, Yuka, Sun, Hong-Wei, Sharpe, Arlene H., Hunter, Christopher A., O'Shea, John J.

“…Interleukin-27 (IL-27) is a key immunosuppressive cytokine that counters T helper 17 (Th17) cell-mediated pathology. To identify mechanisms by which IL-27…”
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The Cytokines Interleukin 27 and Interferon-γ Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology by Hall, Aisling O’Hara, Beiting, Daniel P., Tato, Cristina, John, Beena, Oldenhove, Guillaume, Lombana, Claudia Gonzalez, Pritchard, Gretchen Harms, Silver, Jonathan S., Bouladoux, Nicolas, Stumhofer, Jason S., Harris, Tajie H., Grainger, John, Wojno, Elia D. Tait, Wagage, Sagie, Roos, David S., Scott, Philip, Turka, Laurence A., Cherry, Sara, Reiner, Steven L., Cua, Daniel, Belkaid, Yasmine, Elloso, M. Merle, Hunter, Christopher A.

“…Interferon-γ (IFN-γ) promotes a population of T-bet+ CXCR3+ regulatory T (Treg) cells that limit T helper 1 (Th1) cell-mediated pathology. Our studies…”
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Cytokine- and TCR-Mediated Regulation of T Cell Expression of Ly6C and Sca-1 by DeLong, Jonathan H, Hall, Aisling O'Hara, Konradt, Christoph, Coppock, Gaia M, Park, Jeongho, Harms Pritchard, Gretchen, Hunter, Christopher A

“…Ly6C and Sca-1 (Ly6A/E) are Ly6 family GPI-anchored surface molecules that are differentially expressed by multiple immune populations. Ly6C expression has…”
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Diverse roles for T-bet in the effector responses required for resistance to infection by Harms Pritchard, Gretchen, Hall, Aisling O'Hara, Christian, David A, Wagage, Sagie, Fang, Qun, Muallem, Gaia, John, Beena, Glatman Zaretsky, Arielle, Dunn, William G, Perrigoue, Jacqueline, Reiner, Steven L, Hunter, Christopher A

“…The transcription factor T-bet has been most prominently linked to NK and T cell production of IFN-γ, a cytokine required for the control of a diverse array of…”
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Publisher Correction: Get the IL-17F outta here by O’Hara Hall, Aisling, Towne, Jennifer E., Plevy, Scott E.

“…In the version of this article initially published, a word (“neutraling”) in sentence 2 of paragraph 5 is incorrect. The correct phrase is “...neutralizing…”
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IFNγ signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells by Lee, Hyang-Mi, Fleige, Anne, Forman, Ruth, Cho, Sunglim, Khan, Aly Azeem, Lin, Ling-Li, Nguyen, Duc T, O'Hara-Hall, Aisling, Yin, Zhinan, Hunter, Christopher A, Muller, Werner, Lu, Li-Fan

“…IFNγ signaling drives dendritic cells (DCs) to promote type I T cell (Th1) immunity. Here, we show that activation of DCs by IFNγ is equally crucial for the…”
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Gene coexpression networks reveal a broad role for lncRNAs in inflammatory bowel disease by Johnson, John L, Sargsyan, Davit, Neiman, Eric M, Hart, Amy, Stojmirovic, Aleksandar, Kosoy, Roman, Irizar, Haritz, Suárez-Fariñas, Mayte, Song, Won-Min, Argmann, Carmen, Avey, Stefan, Shmuel-Galia, Liraz, Vierbuchen, Tim, Bongers, Gerold, Sun, Yu, Edelstein, Leonard, Perrigoue, Jacqueline, Towne, Jennifer E, Hall, Aisling O'Hara, Fitzgerald, Katherine A, Hoebe, Kasper

“…The role of long noncoding RNAs (lncRNAs) in disease is incompletely understood, but their regulation of inflammation is increasingly appreciated. We addressed…”
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IL-27 and TCR Stimulation Promote T Cell Expression of Multiple Inhibitory Receptors by DeLong, Jonathan H, O'Hara Hall, Aisling, Rausch, Matt, Moodley, Devapregasan, Perry, Joseph, Park, Jeongho, Phan, Anthony T, Beiting, Daniel P, Kedl, Ross M, Hill, Jonathan A, Hunter, Christopher A

“…Inhibitory receptors (IR) are a diverse group of cell surface molecules that modulate T cell activation, but there are gaps in our knowledge of the…”
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The immunobiology of IL-27 by Hall, Aisling O'Hara, Silver, Jonathan S, Hunter, Christopher A

“…Like many cytokines, IL-27 has pleiotropic properties that can limit or enhance ongoing immune responses depending on context. Thus, under certain…”
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The aryl hydrocarbon receptor promotes IL-10 production by natural killer cells by Wagage, Sagie, John, Beena, Krock, Bryan L., Hall, Aisling O'Hara, Randall, Louise M., Karp, Christopher L., Simon, M. Celeste, Hunter, Christopher A.

“…The cytokine IL-10 has an important role in limiting inflammation in many settings, including toxoplasmosis. In these studies, an IL-10 reporter mouse was used…”
Get full text

IFN[gamma] signaling endows DCs with the capacity to control type I inflammation during parasitic infection through promoting T-bet+ regulatory T cells by Lee, Hyang-Mi, Fleige, Anne, Forman, Ruth, Cho, Sunglim, Khan, Aly Azeem, Lin, Ling-Li, Nguyen, Duc T, O'Hara-Hall, Aisling, Yin, Zhinan, Hunter, Christopher A, Muller, Werner, Lu, Li-Fan

“…IFN[gamma] signaling drives dendritic cells (DCs) to promote type I T cell (Th1) immunity. Here, we show that activation of DCs by IFN[gamma] is equally…”
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The Cytokines Interleukin 27 and Interferon-[gamma] Promote Distinct Treg Cell Populations Required to Limit Infection-Induced Pathology by Hall, Aisling O'Hara, Beiting, Daniel P, Tato, Cristina, John, Beena, Oldenhove, Guillaume, Lombana, Claudia Gonzalez, Pritchard, Gretchen Harms, Silver, Jonathan S, Bouladoux, Nicolas, Stumhofer, Jason S, Harris, Tajie H, Grainger, John, Wojno, Elia D Tait, Wagage, Sagie, Roos, David S, Scott, Philip, Turka, Laurence A, Cherry, Sara, Reiner, Steven L, Cua, Daniel, Belkaid, Yasmine, Elloso, M Merle, Hunter, Christopher A

“…Interferon-γ (IFN-γ) promotes a population of T-bet+CXCR3+regulatory T (Treg) cells that limit T helper 1 (Th1) cell-mediated pathology. Our studies…”
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Ly6C expression on T cells is modulated by IL-27, interferon-gamma and TCR stimulation by DeLong, Jonathan Howard, Hall, Aisling O’Hara, Muallem, Gaia, Hunter, Christopher A

“…Ly6C is a GPI-anchored glycoprotein expressed on a range of hematopoietic cell lineages. On T cells, its expression distinguishes short-lived effector CD4+ T…”
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CD11c-expressing cells affect Treg behavior in the meninges during CNS infection1 by O’Brien, Carleigh A., Overall, Christopher, Konradt, Christoph, O’Hara Hall, Aisling C., Hayes, Nikolas W., Wagage, Sagie, John, Beena, Christian, David A., Hunter, Christopher A., Harris, Tajie H.

“…Treg cells play an important role in the CNS during multiple infections as well as autoimmune inflammation, but the behavior of this cell type in the CNS has…”
Get full text