Search Results - "O'Hara, P."

The relationship between anxiety and acute mountain sickness by Boos, Christopher J, Bass, Malcolm, O'Hara, John P, Vincent, Emma, Mellor, Adrian, Sevier, Luke, Abdul-Razakq, Humayra, Cooke, Mark, Barlow, Matt, Woods, David R

“…Whilst the link between physical factors and risk of high altitude (HA)-related illness and acute mountain sickness (AMS) have been extensively explored, the…”
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Absence of the intestinal microbiota exacerbates hepatobiliary disease in a murine model of primary sclerosing cholangitis by Tabibian, James H., O'Hara, Steven P., Trussoni, Christy E., Tietz, Pamela S., Splinter, Patrick L., Mounajjed, Taofic, Hagey, Lee R., LaRusso, Nicholas F.

“…Primary sclerosing cholangitis (PSC) is a chronic, idiopathic, fibroinflammatory cholangiopathy. The role of the microbiota in PSC etiopathogenesis may be…”
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Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice by Guicciardi, Maria Eugenia, Trussoni, Christy E., Krishnan, Anuradha, Bronk, Steven F., Lorenzo Pisarello, Maria J., O'Hara, Steven P., Splinter, Patrick L., Gao, Yandong, Vig, Pamela, Revzin, Alexander, LaRusso, Nicholas F., Gores, Gregory J.

“…[Display omitted] •Peribiliary macrophages are increased in PSC and animal models of PSC.•Both M1-like and M2-like peribiliary macrophages are…”
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Cholangiocyte senescence by way of N‐ras activation is a characteristic of primary sclerosing cholangitis by Tabibian, James H., O'Hara, Steven P., Splinter, Patrick L., Trussoni, Christy E., LaRusso, Nicholas F.

“…Primary sclerosing cholangitis (PSC) is an incurable cholangiopathy of unknown etiopathogenesis. Here we tested the hypothesis that cholangiocyte senescence is…”
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Impact of Acute Exacerbation of Idiopathic Pulmonary Fibrosis on Lung Transplant Outcomes by Warrior, Krishnan, Sayad, Karen, O'Hara, Christopher P, Dilling, Daniel F

“…Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) are acute, significant respiratory deteriorations in patients with IPF and can lead to increased…”
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Non-intrusive coupling of a 3-D Generalized Finite Element Method and Abaqus for the multiscale analysis of localized defects and structural features by Li, H., O'Hara, P., Duarte, C.A.

“…This paper presents a multiscale computational framework able to resolve localized defects and features such as cracks and welds in large structures. It…”
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Six weeks of dynamic apnoeic training stimulates erythropoiesis but does not increase splenic volume by Elia, Antonis, Barlow, Matthew J., Wilson, Oliver J., O’Hara, John P.

“…Purpose This study examined the influence of dynamic apnoea training on splenic volume and haematological responses in non-breath-hold divers (BHD). Methods…”
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Immunity from NK Cell Subsets Is Important for Vaccine-Mediated Protection in HPV+ Cancers by O'Hara, Madison P, Yanamandra, Ananta V, Sastry, K Jagannadha

“…High-risk human papillomaviruses (HPVs) are associated with genital and oral cancers, and the incidence of HPV+ head and neck squamous cell cancers is fast…”
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Relative changes in brain and kidney biomarkers with Exertional Heat Illness during a cool weather marathon by Stacey, Michael J, Hill, Neil E, Parsons, Iain T, Wallace, Jenny, Taylor, Natalie, Grimaldi, Rachael, Shah, Nishma, Marshall, Anna, House, Carol, O'Hara, John P, Brett, Stephen J, Woods, David R

“…Medical personnel may find it challenging to distinguish severe Exertional Heat Illness (EHI), with attendant risks of organ-injury and longer-term sequalae,…”
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Exceptional Extended Field-of-view Observations by PROBA2/SWAP on 2017 April 1 and 3 by O'Hara, Jennifer P., Mierla, Marilena, Podladchikova, Olena, D'Huys, Elke, West, Matthew J.

“…On 2017 April 1 and 3, two large eruptions on the western solar limb, which were associated with M4.4- and M5.8-class flares, respectively, were observed with…”
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Seabird diet indicates changing Arctic marine communities in eastern Canada by Provencher, J. F., Gaston, A. J., O’Hara, P. D., Gilchrist, H. G.

“…Changing climatic conditions are affecting ecosystems worldwide, but polar ecosystems are experiencing the most rapid changes as the extent of summer sea ice…”
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A Cellular Micro-RNA, let-7i, Regulates Toll-like Receptor 4 Expression and Contributes to Cholangiocyte Immune Responses against Cryptosporidium parvum Infection by Chen, Xian-Ming, Splinter, Patrick L., O'Hara, Steven P., LaRusso, Nicholas F.

“…Toll-like receptors (TLRs) are important pathogen recognition molecules and are key to epithelial immune responses to microbial infection. However, the…”
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Mitigation of anisotropic fatigue in nickel alloy 718 manufactured via selective laser melting by Sabelkin, Volodymyr P., Cobb, Gregory R., Shelton, Travis E., Hartsfield, Megan N., Newell, David J., O’Hara, Ryan P., Kemnitz, Ryan A.

“…The tension-tension fatigue behavior of heat treated selective laser melted (SLM) nickel alloy 718 (IN718) tensile specimens was tested and compared to…”
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Central role for cholangiocyte pathobiology in cholestatic liver diseases by Jalan-Sakrikar, Nidhi, Guicciardi, Maria Eugenia, O'Hara, Steven P, Azad, Adiba, LaRusso, Nicholas F, Gores, Gregory J, Huebert, Robert C

“…Cholangiopathies comprise a spectrum of chronic intra- and extrahepatic biliary tract disorders culminating in progressive cholestatic liver injury, fibrosis…”
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Impacts of anthropogenic noise on marine life: Publication patterns, new discoveries, and future directions in research and management by Williams, R., Wright, A.J., Ashe, E., Blight, L.K., Bruintjes, R., Canessa, R., Clark, C.W., Cullis-Suzuki, S., Dakin, D.T., Erbe, C., Hammond, P.S., Merchant, N.D., O'Hara, P.D., Purser, J., Radford, A.N., Simpson, S.D., Thomas, L., Wale, M.A.

“…Anthropogenic underwater noise is now recognized as a world-wide problem, and recent studies have shown a broad range of negative effects in a variety of taxa…”
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Changes in balance and joint position sense during a 12-day high altitude trek: The British Services Dhaulagiri medical research expedition by Clarke, Sarah B, Deighton, Kevin, Newman, Caroline, Nicholson, Gareth, Gallagher, Liam, Boos, Christopher J, Mellor, Adrian, Woods, David R, O'Hara, John P

“…Postural control and joint position sense are essential for safely undertaking leisure and professional activities, particularly at high altitude. We tested…”
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Energy expenditure of rugby players during a 14-day in-season period, measured using doubly labelled water by Smith, Deborah R., King, R. F. G. J., Duckworth, L. C., Sutton, L., Preston, T., O’Hara, J. P., Jones, B.

“…Criterion data for total energy expenditure (TEE) in elite rugby are lacking, which prediction equations may not reflect accurately. This study quantified TEE…”
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A preliminary spatial assessment of risk: Marine birds and chronic oil pollution on Canada's Pacific coast by Fox, C.H., O'Hara, P.D., Bertazzon, S., Morgan, K., Underwood, F.E., Paquet, P.C.

“…Chronic oil pollution poses substantial risks to marine birds and other marine wildlife worldwide. On Canada's Pacific coast, the negative ecological…”
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Endothelial cell toll‐like receptor 4 regulates fibrosis‐associated angiogenesis in the liver by Jagavelu, Kumaravelu, Routray, Chittaranjan, Shergill, Uday, O'Hara, Steven P., Faubion, William, Shah, Vijay H.

“…Angiogenesis defines the growth of new blood vessels from preexisting vascular endothelial networks and corresponds to the wound healing process that is…”
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Transient analysis of sharp thermal gradients using coarse finite element meshes by O’Hara, P., Duarte, C.A., Eason, T.

“…This paper investigates the application of the generalized finite element method with global–local enrichments ( GFEM gl) to problems of transient heat…”
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