Search Results - "O'Hara, Carl"

Integration of Basic Science and Clinical Medicine: The Innovative Approach of the Cadaver Biopsy Project at the Boston University School of Medicine by Eisenstein, Anna, Vaisman, Lev, Johnston-Cox, Hillary, Gallan, Alexander, Shaffer, Kitt, Vaughan, Deborah, O’Hara, Carl, Joseph, Lija

“…PROBLEMCurricular integration has emerged as a consistent theme in medical education reform. Vertical integration of topics such as pathology offers the…”
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Amyloidosis of the gastrointestinal tract: a 13-year, single-center, referral experience by Cowan, Andrew J, Skinner, Martha, Seldin, David C, Berk, John L, Lichtenstein, David R, O'Hara, Carl J, Doros, Gheorghe, Sanchorawala, Vaishali

“…Amyloidosis of the gastrointestinal tract, with biopsy-proven disease, is rare. We reviewed a series of patients who presented with biopsy-proven…”
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Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis by Ward, Jennifer Ellis, Ren, Ruiyi, Toraldo, Gianluca, SooHoo, Pam, Guan, Jian, O'Hara, Carl, Jasuja, Ravi, Trinkaus-Randall, Vickery, Liao, Ronglih, Connors, Lawreen H., Seldin, David C.

“…Systemic AL amyloidosis results from the aggregation of an amyloidogenic immunoglobulin (Ig) light chain (LC) usually produced by a plasma cell clone in the…”
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Extranodal Marginal Zone Endobronchial Lymphoma Associated With Hepatitis C by Bhatt, Nimish, BA, Sloan, J. Mark, MD, O’Hara, Carl J., MD, Oommen, Roy, MD, Steiling, Katrina, MD, Litle, Virginia R., MD

“…We describe two patients with hepatitis C and a diagnosis of pulmonary extranodal marginal zone B cell lymphoma. Both patients demonstrated a chronic…”
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Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis by Connors, Lawreen H., PhD, Prokaeva, Tatiana, MD, PhD, Lim, Amareth, PhD, Théberge, Roger, PhD, Falk, Rodney H., MD, Doros, Gheorghe, PhD, Berg, Alan, MD, Costello, Catherine E., PhD, O'Hara, Carl, MD, Seldin, David C., MD, PhD, Skinner, Martha, MD

“…Background Transthyretin (TTR) mutations known to cause cardiac amyloidosis include V122I, found almost exclusively in African Americans at a prevalence of…”
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miRNA profiling of primary lung and head and neck squamous cell carcinomas: Addressing a diagnostic dilemma by Muñoz-Largacha, Juan A., MD, Gower, Adam C., PhD, Sridhar, Praveen, MD, Deshpande, Anita, MD, O'Hara, Carl J., MD, Yamada, Emiko, BA, Godfrey, Tony E., PhD, Fernando, Hiran C., MD, Litle, Virginia R., MD

“…Abstract Objective To determine whether microRNA (miRNA) profiling of primary lung and head and neck squamous cell carcinomas could be useful to identify a…”
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Surgical Management of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Associated With Light-Chain Deposition Disease by Muñoz-Largacha, Juan A., MD, O’Hara, Carl J., MD, Sloan, J. Mark, MD, Fernando, Hiran C., MD, Litle, Virginia R., MD

“…A 52-year-old woman presented with a right middle lobe (RML) lung nodule suspicious for malignancy. Thoracoscopic middle lobectomy was performed. The pathology…”
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Transbronchial biopsies safely diagnose amyloid lung disease by Govender, Praveen, Keyes, Colleen M., Hankinson, Elizabeth A., O'Hara, Carl J., Sanchorawala, Vaishali, Berk, John L.

“…Background: Autopsy identifies lung involvement in 58-92% of patients with the most prevalent forms of systemic amyloidoses. In the absence of lung biopsies,…”
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Hereditary Renal Amyloidosis Associated With a Novel Apolipoprotein A-II Variant by Prokaeva, Tatiana, Akar, Harun, Spencer, Brian, Havasi, Andrea, Cui, Haili, O'Hara, Carl J, Gursky, Olga, Leszyk, John, Steffen, Martin, Browning, Sabrina, Rosenberg, Allison, Connors, Lawreen H

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Endotracheal hamartoma case report: Two contrasting clinical presentations of a rare entity by Hon, Curtis, O’Hara, Carl J., Litle, Virginia R.

“…•Hamartomas are benign tumors that are rarely localized to the trachea.•Symptoms often gradual, mimicking those of chronic obstructive pulmonary…”
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ETS1 regulates Twist1 transcription in a KrasG12D/Lkb1−/− metastatic lung tumor model of non-small cell lung cancer by Millien, Guetchyn, Cao, Yuxia, O’Hara, Carl J., Tagne, Jean-Bosco, Hinds, Anne, Williams, Mary C., Ramirez, Maria I., Kathuria, Hasmeena

“…Distinct members of the Ets family of transcription factors act as positive or negative regulators of genes involved in cellular proliferation, development,…”
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Bone marrow core biopsy specimens in AL (primary) amyloidosis: A morphologic and immunohistochemical study of 100 cases by SWAN, Niall, SKINNER, Martha, O'HARA, Carl J

“…We retrospectively reviewed 100 bone marrow core biopsy specimens from patients with AL (primary) amyloidosis. The morphologic and immunohistochemical features…”
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Localized amyloidosis of the breast: a case series by Charlot, Marjory, Seldin, David C., O'hara, Carl, Skinner, Martha, Sanchorawala, Vaishali

“…We report on the clinical presentation and histopathology of a series of seven patients with localized amyloidosis of the breast. These patients were diagnosed…”
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A new lysozyme tyr54asn mutation causing amyloidosis in a family of Swedish ancestry with gastrointestinal symptoms by Girnius, Saulius, Skinner, Martha, Spencer, Brian, Prokaeva, Tatiana, Bartholomew, Catherine, O'Hara, Carl, Seldin, David C., Connors, Lawreen H.

“…Familial amyloidoses are a group of inherited disorders that cause deposition of misfolded amyloidogenic proteins in various tissues, resulting in organ…”
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Simultaneous presentation of kappa-restricted chronic lymphocytic leukemia and lambda light chain AL amyloidosis by von Keudell, Gottfried, Sanchorawala, Vaishali, O'Hara, Carl, C. Seldin, David, Sloan, J. Mark

“…Abstract We report on a 58-year-old man who presented with simultaneous kappa-restricted chronic lymphocytic leukemia (CLL) and a lambda-restricted plasma cell…”
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Matrix metalloproteinases and their tissue inhibitors in cardiac amyloidosis: relationship to structural, functional myocardial changes and to light chain amyloid deposition by Biolo, Andreia, Ramamurthy, Sujata, Connors, Lawreen H, O'Hara, Carl J, Meier-Ewert, Hans K, Soo Hoo, Pamela T, Sawyer, Douglas B, Seldin, David C, Seldin, David S, Sam, Flora

“…Cardiac amyloidosis is characterized by amyloid infiltration resulting in extracellular matrix disruption. Amyloid cardiomyopathy due to immunoglobulin light…”
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Metastatic Interdigitating Dendritic Cell Sarcoma Masquerading as a Skin Primary Tumor : A Case Report and Review of the Literature by LEE, John C, CHRISTENSEN, Tom, O'HARA, Carl J

“…We report an unusual case of a lymph node interdigitating dendritic cell sarcoma (IDCS), metastatic to skin, in a 73-year-old patient. The patient initially…”
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ETS1 regulates Twist1 transcription in a Kras G12D /Lkb1 -/- metastatic lung tumor model of non-small cell lung cancer by Millien, Guetchyn, Cao, Yuxia, O'Hara, Carl J, Tagne, Jean-Bosco, Hinds, Anne, Williams, Mary C, Ramirez, Maria I, Kathuria, Hasmeena

“…Distinct members of the Ets family of transcription factors act as positive or negative regulators of genes involved in cellular proliferation, development,…”
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Dysregulation of miRNAs in AL amyloidosis by Weng, Liangping, Spencer, Brian H., SoohHoo, Pamela T., Connors, Lawreen H., O'Hara, Carl J., Seldin, David C.

“…Bone marrow plasma cells (BMPCs) were purified using anti-CD138 immunomagnetic beads, from aspirates obtained with permission of the Boston University Medical…”
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Gamma heavy chain disease in a patient with underlying lymphoplasmacytic lymphoma of the thyroid. Report of a case and comparison with other reported cases with thyroid involvement by Tan, Josenia N.M., Kroll, Martin H., O'Hara, Carl J., Everett, Peter C., Erdogan, Evrim

“…Gamma heavy chain disease with underlying thyroid pathology is rare. There are 5 reported cases in the English literature, including the present case of an…”
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