Search Results - "O'Grady, R L"

Epithelial cells up-regulate matrix metalloproteinases in cells within the same mammary carcinoma that have undergone an epithelial-mesenchymal transition by MARTORANA, A. M, GUOPING ZHENG, CROWE, T. C, O'GRADY, R. L, LYONS, J. G

“…A metastatic rat mammary carcinoma cell line, BC1, contains cells that have retained epithelial differentiation characteristics and metaplastic cells that have…”
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Absolute quantitation of specific mRNAs in cell and tissue samples by comparative PCR by Martorana, A M, Zheng, G, Springall, F, Iland, H J, O'Grady, R L, Lyons, J G

“…A comparative PCR assay, for the absolute quantitation of specific mRNAs in cell and tissue samples, has been designed to overcome problems with previous…”
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Characteristics of a 95-kDa matrix metalloproteinase produced by mammary carcinoma cells by Lyons, J. Guy, Birkedal-Hansen, Bente, Moore, William G. I, O'Grady, Robert L, Birkedal-Hansen, Henning

“…A Mr 95,000 matrix metalloproteinase (MMP) produced by rat mammary carcinoma cells has been isolated and characterized. The MMP was secreted in a…”
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Immunolocalization of collagenase in neoplastic epithelial cells by Whitelock, J M, O'Grady, R L, Lyons, J G

“…The distribution of interstitial collagenase in a rat mammary carcinoma model system has been studied by immunocytochemistry. Rabbit antibodies were raised…”
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Cellular interactions determining the production of collagenase by a rat mammary carcinoma cell line by Lyons, J G, Siew, K, O'Grady, R L

“…The cellular interactions regulating the production of collagenase by a cell line derived from a spontaneously arising rat mammary carcinoma have been studied…”
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Multiple levels of post-transcriptional regulation of collagenase (matrix metalloproteinase 1) in an epithelial cell line by Whitelock, J M, Paine, M L, Gibbins, J R, Kefford, R F, O'Grady, R L

“…Multiple levels of regulation of collagenase (matrix metalloproteinase 1; MMP-1), have been demonstrated in a clonal rat epithelial cell line (A5P/B10)…”
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Unregulated and independent expression of collagenase and transin related to tumor progression by Paine, M L, Gibbins, J R, Whitelock, J M, O'Grady, R L, Kefford, R F

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Transplantation and tissue culture studies of radiation-induced osteosarcoma in the rat by Geddes-Dwyer, V, Bosanquet, J S, O'Grady, R L, Cameron, D A

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The chondroprotective drugs, Arteparon and sodium pentosan polysulphate, increase collagenase activity and inhibit stromelysin activity in vitro by Nethery, A, Giles, I, Jenkins, K, Jackson, C, Brooks, P, Burkhardt, D, Ghosh, P, Whitelock, J, O'Grady, R L, Welgus, H G

“…The effects of the chondroprotective drugs, sodium pentosan polysulphate (SP54) and Arteparon (glycosaminoglycan polysulphate), on the in vitro activities of…”
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Osteoclasts and the resorption of bone by transplanted mammary carcinoma in rats by ÓGRADY, R. L, CAMERON, D. A

“…Rat mammary tumour cells were grafted to parietal bones as an experimental model to study the nature of bone resorption around metastatic carcinomas in the…”
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A spectrophotometric collagenase assay by Nethery, A, Lyons, J G, O'Grady, R L

“…A quantitative collagenase assay using Coomassie blue staining and microtiter spectrophotometry is described. Collagen is gelled and dried onto the bottom of…”
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Identification, partial purification and characterization of high-molecular-weight gelatin-degrading metalloproteinases produced by a rat mammary carcinoma cell line by Nethery, A, O'Grady, R L

“…BC1 rat mammary carcinoma cells were found to secrete a unique profile of metalloproteinases, distinguished by two gelatin-degrading metalloproteinases of Mr…”
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Rat mammary carcinoma cells secrete active collagenase and activate latent enzyme in the stroma via plasminogen activator by O'Grady, R L, Upfold, L I, Stephens, R W

“…A spontaneous mammary adenocarcinoma (AC) from an inbred female rat was investigated with regard to secretion of neutral proteases. Cultures of neoplastic…”
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The identification, purification and characterisation of an inhibitor of collagenase (20K) produced by neoplastic epithelial cells by Whitelock, J M, O'Grady, R L, Gibbins, J R

“…A rat carcinoma cell line (T2/H7) constitutively synthesised interstitial collagenase. When these cells were incubated with 12-O-tetradecanoylphorbol…”
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Interstitial collagenase (matrix metalloproteinase 1) associated with the plasma membrane of both neoplastic and nonneoplastic cells by Whitelock, J M, O'Grady, R L, Gibbins, J R

“…Epithelial cell lines (BC1, BC3, BC4, and BC5), derived from 4 separate invasive and metastatic rat mammary carcinomas, all secreted interstitial collagenase…”
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Interstitial collagenase from rat mammary carcinoma cells: interaction with substrates and inhibitors by Nethery, A, O'Grady, R L

“…Functional characteristics of the interstitial collagenase purified from the BCl rat mammary carcinoma cell line were examined and compared with literature…”
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The production of collagenase and an inhibitor of collagenase by rat mammary carcinoma cells by Whitelock, J M, O'Grady, R L

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Rat carcinoma cells in long-term, serum-free culture provide a continuing supply of collagenase by Stevenson, G A, Lyons, J G, Cameron, D A, O'Grady, R L

“…Neoplastic, epithelial cells derived from a spontaneously-arising rat mammary carcinoma have been cultured in a defined medium, in the absence of serum,…”
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Stimulation of lysosomal enzyme release from macrophages by lipoteichoic acid by Harrop, P J, O'Grady, R L, Knox, K W, Wicken, A J

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Studies on the binding of lipoteichoic acid to osseous tissue by O'Grady, R L, Harrop, P J, Knox, K W, Wicken, A J

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