Search Results - "O'Dwyer, David N"

Reply to Fujimoto et al. : Leveraging Microbiome Composition Variability for Precision Medicine in Idiopathic Pulmonary Fibrosis by O'Dwyer, David N, Noth, Imre, Oldham, Justin M

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Reply to Ward et al. : Integrating Aerodigestive Investigations in Progressive Pulmonary Fibrosis by O'Dwyer, David N, Kim, John S, Noth, Imre

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Influences of innate immunity, autophagy, and fibroblast activation in the pathogenesis of lung fibrosis by O'Dwyer, David N, Ashley, Shanna L, Moore, Bethany B

“…Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial lung disease characterized by accumulation of extracellular matrix (ECM) and impaired gas…”
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Methods in Lung Microbiome Research by Carney, Sharon M, Clemente, Jose C, Cox, Michael J, Dickson, Robert P, Huang, Yvonne J, Kitsios, Georgios D, Kloepfer, Kirsten M, Leung, Janice M, LeVan, Tricia D, Molyneaux, Philip L, Moore, Bethany B, O'Dwyer, David N, Segal, Leopoldo N, Garantziotis, Stavros

“…The lung microbiome is associated with host immune response and health outcomes in experimental models and patient cohorts. Lung microbiome research is…”
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The Toll-like Receptor 3 L412F Polymorphism and Disease Progression in Idiopathic Pulmonary Fibrosis by O'DWYER, David N, ARMSTRONG, Michelle E, HIRANI, Nik, HOGABOAM, Cory M, DONNELLY, Seamas C, TRUJILLO, Glenda, COOKE, Gordon, KEANE, Michael P, FALLON, Padraic G, SIMPSON, A. John, MILLAR, Ann B, MCGRATH, Emmet E, WHYTE, Moira K

“…Idiopathic pulmonary fibrosis (IPF) is a fatal progressive interstitial pneumonia. The innate immune system provides a crucial function in the recognition of…”
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Six-SOMAmer Index Relating to Immune, Protease and Angiogenic Functions Predicts Progression in IPF by Ashley, Shanna L, Xia, Meng, Murray, Susan, O'Dwyer, David N, Grant, Ethan, White, Eric S, Flaherty, Kevin R, Martinez, Fernando J, Moore, Bethany B

“…Biomarkers in easily accessible compartments like peripheral blood that can predict disease progression in idiopathic pulmonary fibrosis (IPF) would be…”
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Commensal Oral Microbiota, Disease Severity, and Mortality in Fibrotic Lung Disease by O'Dwyer, David N, Kim, John S, Ma, Shwu-Fan, Ranjan, Piyush, Das, Promi, Lipinski, Jay H, Metcalf, Joseph D, Falkowski, Nicole R, Yow, Eric, Anstrom, Kevin, Dickson, Robert P, Huang, Yong, Gilbert, Jack A, Martinez, Fernando J, Noth, Imre

“…Oral microbiota associate with diseases of the mouth and serve as a source of lung microbiota. However, the role of oral microbiota in lung disease is unknown…”
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Pulmonary immunity and extracellular matrix interactions by O'Dwyer, David N., Gurczynski, Stephen J., Moore, Bethany B.

“…The lung harbors a complex immune system composed of both innate and adaptive immune cells. Recognition of infection and injury by receptors on lung innate…”
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Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis by McElroy, Aoife N, Invernizzi, Rachele, Laskowska, Joanna W, O'Neill, Andrew, Doroudian, Mohammad, Moghoofei, Mohsen, Mostafaei, Shayan, Li, Feng, Przybylski, Alexander A, O'Dwyer, David N, Bowie, Andrew G, Fallon, Padraic G, Maher, Toby M, Hogaboam, Cory M, Molyneaux, Philip L, Hirani, Nik, Armstrong, Michelle E, Donnelly, Seamas C

“…The Toll-like receptor 3 Leu412Phe ( L412F) polymorphism attenuates cellular antiviral responses and is associated with accelerated disease progression in…”
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Proceedings of the American College of Rheumatology/Association of Physicians of Great Britain and Ireland Connective Tissue Disease–Associated Interstitial Lung Disease Summit: A Multidisciplinary Approach to Address Challenges and Opportunities by Fischer, Aryeh, Strek, Mary E., Cottin, Vincent, Dellaripa, Paul F., Bernstein, Elana J., Brown, Kevin K., Danoff, Sonye K., Distler, Oliver, Hirani, Nik, Jones, Kirk D., Khanna, Dinesh, Lee, Joyce S., Lynch, David A., Maher, Toby M., Millar, Ann B., Raghu, Ganesh, Silver, Richard M., Steen, Virginia D., Volkmann, Elizabeth R., Mullan, Ronan H., O'Dwyer, David N., Donnelly, Seamas C.

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Loss of CCR2 signaling alters leukocyte recruitment and exacerbates γ-herpesvirus-induced pneumonitis and fibrosis following bone marrow transplantation by Gurczynski, Stephen J, Procario, Megan C, O'Dwyer, David N, Wilke, Carol A, Moore, Bethany B

“…CCR2-expressing leukocytes are required for the progression of fibrosis in models of induced lung injury as well as models of bone marrow transplant…”
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Pretransplant Antifibrotic Therapy Is Associated with Resolution of Primary Graft Dysfunction by Combs, Michael P, Fitzgerald, Linda J, Wakeam, Elliot, Lyu, Dennis M, O'Dwyer, David N

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Concurrent Reductions in Spirometry Predict Mortality and Bronchiolitis Obliterans in Chronic Graft-versus-Host Disease by O'Dwyer, David N, Wang, Yizhuo, Myers, Dawson, Moore, Bethany B, Murray, Susan, Yanik, Gregory A

“…Chronic grart-versus-host disease (cGVHD) is a poorly understood complication of hematopoietic cell transplantation (HCT) and a leading cause of mortality…”
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The role of periostin in lung fibrosis and airway remodeling by O’Dwyer, David N., Moore, Bethany B.

“…Periostin is a protein that plays a key role in development and repair within the biological matrix of the lung. As a matricellular protein that does not…”
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The Lung Microbiome, Immunity, and the Pathogenesis of Chronic Lung Disease by O'Dwyer, David N, Dickson, Robert P, Moore, Bethany B

“…The development of culture-independent techniques for microbiological analysis has uncovered the previously unappreciated complexity of the bacterial…”
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Lung Microbiota Contribute to Pulmonary Inflammation and Disease Progression in Pulmonary Fibrosis by O'Dwyer, David N, Ashley, Shanna L, Gurczynski, Stephen J, Xia, Meng, Wilke, Carol, Falkowski, Nicole R, Norman, Katy C, Arnold, Kelly B, Huffnagle, Gary B, Salisbury, Margaret L, Han, MeiLan K, Flaherty, Kevin R, White, Eric S, Martinez, Fernando J, Erb-Downward, John R, Murray, Susan, Moore, Bethany B, Dickson, Robert P

“…Idiopathic pulmonary fibrosis (IPF) causes considerable global morbidity and mortality, and its mechanisms of disease progression are poorly understood. Recent…”
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It’s getting hot in here: The interface between obesity, influenza, and thermoneutrality by O'Dwyer, David N., Hogan, Simon P.

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The evolving role of the lung microbiome in pulmonary fibrosis by Lipinski, Jay H, Moore, Bethany B, O'Dwyer, David N

“…Mucosal surfaces are constantly exposed to a microbiome consisting of microorganisms that heavily influence human immunity and health. In the lung these…”
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The Lung Microbiome in Health, Hypersensitivity Pneumonitis, and Idiopathic Pulmonary Fibrosis: A Heavy Bacterial Burden to Bear by O'Dwyer, David N, Garantziotis, Stavros

“…The microbiome regulates human health and immunity, contributing robustly to physiological homeostasis. The healthy lung is not sterile and consists of…”
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The Lung Microbiome by Lipinksi, Jay H, Ranjan, Piyush, Dickson, Robert P, O'Dwyer, David N

“…Although the lungs were once considered a sterile environment, advances in sequencing technology have revealed dynamic, low-biomass communities in the…”
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