Search Results - "O'Dorisio, M"
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Technical Note: Single time point dose estimate for exponential clearance
Published in Medical physics (Lancaster) (01-05-2018)“…Objective Although personalized dosimetry may be desirable for radionuclide therapy treatments, the multiple time samples required to determine the total…”
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Evolution of Neuroendocrine Tumor Therapy
Published in Surgical oncology clinics of North America (01-04-2020)“…To better understand developments in treatment of neuroendocrine tumors of the gastroenteropancreatic system, and the pivotal roles of native somatostatin and…”
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Pancreastatin Predicts Survival in Neuroendocrine Tumors
Published in Annals of surgical oncology (01-09-2014)“…Background Serum neurokinin A, chromogranin A, serotonin, and pancreastatin reflect tumor burden in neuroendocrine tumors. We sought to determine whether their…”
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Gastric inhibitory polypeptide receptor (GIPR) is a promising target for imaging and therapy in neuroendocrine tumors
Published in Surgery (01-12-2013)“…Background Ligands binding the somatostatin receptor type 2 (SSTR2) are useful for imaging and treatment of neuroendocrine tumors (NETs), but not all tumors…”
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Peptide Receptor Radionuclide Therapy Improves Survival in Patients Who Progress After Resection of Gastroenteropancreatic Neuroendocrine Tumors
Published in Annals of surgical oncology (06-11-2024)“…Peptide receptor radionuclide therapy (PRRT) is an effective treatment for advanced gastroenteropancreatic (GEP) neuroendocrine tumors (NETs). We investigated…”
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The North American Neuroendocrine Tumor Society consensus guideline for the diagnosis and management of neuroendocrine tumors: pheochromocytoma, paraganglioma, and medullary thyroid cancer
Published in Pancreas (01-08-2010)“…Pheochromocytomas, intra-adrenal paraganglioma, and extra-adrenal sympathetic and parasympathetic paragangliomas are neuroendocrine tumors derived from adrenal…”
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Gene expression accurately distinguishes liver metastases of small bowel and pancreas neuroendocrine tumors
Published in Clinical & experimental metastasis (01-12-2014)“…Small bowel (SBNETs) and pancreatic neuroendocrine tumors (PNETs) often present with liver metastases. Although liver biopsy establishes a neuroendocrine…”
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Addition of 131 I-MIBG to PRRT ( 90 Y-DOTATOC) for Personalized Treatment of Selected Patients with Neuroendocrine Tumors
Published in Journal of Nuclear Medicine (01-09-2021)“…Peptide receptor radionuclide therapy (PRRT) is an effective treatment for metastatic neuroendocrine tumors. Delivering a sufficient tumor radiation dose…”
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Auranofin inhibition of thioredoxin reductase sensitizes lung neuroendocrine tumor cells (NETs) and small cell lung cancer (SCLC) cells to sorafenib as well as inhibiting SCLC xenograft growth
Published in Cancer biology & therapy (31-12-2024)“…Thioredoxin Reductase (TrxR) functions to recycle thioredoxin (Trx) during hydroperoxide metabolism mediated by peroxiredoxins and is currently being targeted…”
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Incidence, survival, and prevalence of neuroendocrine tumors versus neuroblastoma in children and young adults: Nine standard SEER registries, 1975-2006
Published in Pediatric blood & cancer (01-01-2011)“…Background The incidence, survival, and prevalence of neuroendocrine tumors (NETs) in children were determined as a first step in improving diagnosis and…”
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The North American Neuroendocrine Tumor Society Consensus Guidelines for Surveillance and Medical Management of Pancreatic Neuroendocrine Tumors
Published in Pancreas (01-08-2020)“…This article is the result of the North American Neuroendocrine Tumor Society consensus conference on the medical management of pancreatic neuroendocrine…”
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Safety and Efficacy of Peptide-Receptor Radionuclide Therapy in Elderly Neuroendocrine Tumor Patients
Published in Cancers (15-12-2021)“…Peptide receptor radionuclide therapy (PRRT) is a well-established treatment in somatostatin receptor-expressing neuroendocrine tumours (NETs). The safety and…”
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Chemokine Receptor CXCR4 Radioligand Targeted Therapy Using 177Lutetium-pentixather for Pulmonary Neuroendocrine Cancers
Published in Radiation research (21-11-2023)“…Intermediate to high-grade lung neuroendocrine tumors (NETs; i.e., atypical carcinoid tumors) and neuroendocrine carcinomas (NECs) are currently difficult to…”
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VPAC1 receptor (Vipr1)-deficient mice exhibit ameliorated experimental autoimmune encephalomyelitis, with specific deficits in the effector stage
Published in Journal of neuroinflammation (29-06-2016)“…Vasoactive intestinal peptide (VIP) and pituitary adenylyl cyclase-activating polypeptide (PACAP) are two highly homologous neuropeptides. In vitro and ex vivo…”
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Addition of 131I-MIBG to PRRT (90Y-DOTATOC) for Personalized Treatment of Selected Patients with Neuroendocrine Tumors
Published in The Journal of nuclear medicine (1978) (01-09-2021)“…Peptide receptor radionuclide therapy (PRRT) is an effective treatment for metastatic neuroendocrine tumors. Delivering a sufficient tumor radiation dose…”
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Journal Article -
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GIPR expression in gastric and duodenal neuroendocrine tumors
Published in The Journal of surgical research (01-08-2014)“…Abstract Background Compounds targeting somatostatin-receptor-type-2 ( SSTR2 ) are useful for small bowel neuroendocrine tumor (SBNET) and pancreatic…”
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Daily Oral Everolimus Activity in Patients With Metastatic Pancreatic Neuroendocrine Tumors After Failure of Cytotoxic Chemotherapy: A Phase II Trial
Published in Journal of clinical oncology (01-01-2010)“…PURPOSE No established treatment exists for pancreatic neuroendocrine tumor (NET) progression after failure of chemotherapy. Everolimus (RAD001), an oral…”
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Establishment of Novel Neuroendocrine Carcinoma Patient-Derived Xenograft Models for Receptor Peptide-Targeted Therapy
Published in Cancers (10-04-2022)“…Gastroenteropancreatic neuroendocrine neoplasms (GEP NENs) are rare cancers consisting of neuroendocrine carcinomas (NECs) and neuroendocrine tumors (NETs),…”
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Differentiation of small bowel and pancreatic neuroendocrine tumors by gene-expression profiling
Published in Surgery (01-12-2012)“…Background Between 10% and 20% of patients with neuroendocrine tumors (NETs) present with metastases of unknown primary site. Because knowledge of the primary…”
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