Search Results - "O'Donovan, Helen"

CCN2/CTGF increases expression of miR-302 microRNAs, which target the TGFβ type II receptor with implications for nephropathic cell phenotypes by Faherty, Noel, Curran, Simon P, O'Donovan, Helen, Martin, Finian, Godson, Catherine, Brazil, Derek P, Crean, John K

“…Signalling interplay between transforming growth factor-β (TGFβ) and CCN2 [also called connective tissue growth factor (CTGF)] plays a crucial role in the…”
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Is Endoscopic Band Ligation a Superior Treatment Modality for Gastric Antral Vascular Ectasia Compared to Argon Plasma Coagulation? by O'Morain, Neil Robert, O'Donovan, Helen, Conlon, Caroline, Shannon, Eileen, Manning, Diarmuid, Slattery, Eoin

“…Gastric antral vascular ectasia (GAVE) is a rare acquired vascular lesion of the gastric antrum. The most frequent presentation of GAVE is iron deficiency…”
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CTGF/CCN2 activates canonical Wnt signalling in mesangial cells through LRP6: Implications for the pathogenesis of diabetic nephropathy by Rooney, Brian, O’Donovan, Helen, Gaffney, Andrew, Browne, Marie, Faherty, Noel, Curran, Simon P., Sadlier, Denise, Godson, Catherine, Brazil, Derek P., Crean, John

“…We describe the activation of Wnt signalling in mesangial cells by CCN2. CCN2 stimulates phosphorylation of LRP6 and GSK-3β resulting in accumulation and…”
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Insulin receptor substrate‐2 is expressed in kidney epithelium and up‐regulated in diabetic nephropathy by Hookham, Michelle B., O'Donovan, Helen C., Church, Rachel H., Mercier‐Zuber, Annie, Luzi, Lucilla, Curran, Simon P., Carew, Rosemarie M., Droguett, Alejandra, Mezzano, Sergio, Schubert, Markus, White, Morris F., Crean, John K., Brazil, Derek P.

“…Diabetic nephropathy (DN) is a progressive fibrotic condition that may lead to end‐stage renal disease and kidney failure. Transforming growth factor‐β1 and…”
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Connective tissue growth factor antagonizes transforming growth factor-β1/Smad signalling in renal mesangial cells by O'Donovan, Helen C, Hickey, Fionnuala, Brazil, Derek P, Kavanagh, David H, Oliver, Noelynn, Martin, Finian, Godson, Catherine, Crean, John

“…The critical involvement of TGF-β1 (transforming growth factor-β1) in DN (diabetic nephropathy) is well established. However, the role of CTGF (connective…”
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TGFβ and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation by Faherty, Noel, O'Donovan, Helen, Kavanagh, David, Madden, Stephen, McKay, Gareth J, Maxwell, Alexander P, Martin, Finian, Godson, Catherine, Crean, John

“…CCN2/CTGF is an established effector of TGFβ driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGFβ leading to…”
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Effects of RACK1 on cell migration and IGF-I signalling in cardiomyoctes are not dependent on an association with the IGF-IR by O'Donovan, Helen C., Kiely, Patrick A., O'Connor, Rosemary

“…RACK1 can act as a scaffolding protein to integrate IGF-IR and integrin signalling in transformed cells but its actions in regulating IGF-IR signalling in…”
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DNA methylation profiling in cell models of diabetic nephropathy by Brennan, Eoin P, Ehrich, Mathias, O'Donovan, Helen, Brazil, Derek P, Crean, John K, Murphy, Madeline, Sadlier, Denise M, Martin, Finian, Godson, Catherine, van den Boom, Dirk, Maxwell, Alexander P, Savage, David A

“…We have previously identified differentially expressed genes in cell models of diabetic nephropathy and renal biopsies. Here we have performed quantitative DNA…”
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Tu1935 DOES THE USE OF ANGIOTENSIN RECEPTOR BLOCKERS (ARB) IN ESTABLISHED COELIAC DISEASE IMPACT UPON THE ASSESSMENT OF DISEASE ACTIVITY? by O'Morain, Neil, McManus, John A., Warner, Vanessa, O'Donovan, Helen, Egan, Brian J., Byrnes, Valerie

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The strategic use of biopsy in the diagnosis of coeliac disease in adults by Deane, Charlene, O'Connor, Eoghan, O'Donovan, Helen, McHale, Ciaran, Alvain, Aoife, Shannon, Eileen, Tormey, Vincent, Hynes, Sean O, Byrnes, Valerie

“…The paediatric guidelines support the use of the 'No Biopsy Approach' in the diagnosis of coeliac disease (CD). We aimed to determine the correlation between…”
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D-lactic acidosis presenting as metabolic encephalopathy in a patient with short bowel syndrome by McHale, Ciarán, Keating, Eoin, O'Donovan, Helen, Slattery, Eoin

“…We present a case of D-lactic acidosis presenting as a metabolic encephalopathy secondary to small intestinal bacterial overgrowth. This patient had a known…”
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Coeliac disease enteropathy and symptoms may be aggravated by angiotensin receptor blockers in patients on a gluten‐free diet by O'Morain, Neil, Shannon, Eileen, McManus, John, Warner, Vanessa, Leeson, Hilary, O'Donovan, Helen, Egan, Brian, Byrnes, Valerie

“…Background Angiotensin receptor blocker‐associated enteropathy (ARB‐e) is an increasingly recognised clinical entity with symptoms and histological findings…”
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TGF[beta] and CCN2/CTGF mediate actin related gene expression by differential E2F1/CREB activation by Faherty, Noel, O'Donovan, Helen, Kavanagh, David, Madden, Stephen, McKay, Gareth J, Maxwell, Alexander P, Martin, Finian, Godson, Catherine, Crean, John

“…CCN2/CTGF is an established effector of TGF[beta] driven responses in diabetic nephropathy. We have identified an interaction between CCN2 and TGF[beta]…”
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Effects of furosemide on body water compartments in infants with bronchopulmonary dysplasia by O'DONOVAN, B. H, BELL, E. F

“…We studied the effects of a single dose of intravenous furosemide on the body water compartments of nine infants with bronchopulmonary dysplasia. We measured…”
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Case Studies of LSS in Higher Education by Murphy, Tom, McNulty, John, O'Dubhghaill, Ronan, O'Reilly, Seamus, O'Donovan, Helen, Healy, Joe, Li, Na, Laux, Chad, Antony, Jiju, Sunder M, Vijaya

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Wrong signpost by O'DONOVAN, HELEN

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DNA methylation profiling in cell models of diabetic nephropathy by Brennan, Eoin P., Ehrich, Mathias, O'Donovan, Helen, Brazil, Derek P., Crean, John K., Murphy, Madeline, Sadlier, Denise M., Martin, Finian, Godson, Catherine, van den Boom, Dirk, Maxwell, Alexander P., Savage, David A.

“…We have previously identified differentially expressed genes in cell models of diabetic nephropathy and renal biopsies. Here we have performed quantitative DNA…”
Get full text