Search Results - "O'Donnell, Anna"
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Maturation of heart valve cell populations during postnatal remodeling
Published in Development (Cambridge) (12-03-2019)“…Heart valve cells mediate extracellular matrix (ECM) remodeling during postnatal valve leaflet stratification, but phenotypic and transcriptional diversity of…”
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The versican-hyaluronan complex provides an essential extracellular matrix niche for Flk1+ hematoendothelial progenitors
Published in Matrix biology (01-03-2021)“…•Versican- and hyaluronan-deficient mouse mutants fail to form yolk sac vasculature and blood.•Mouse embryonic stem cells with CRISPR-Cas9 Vcan mutation have…”
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Localized Prox1 Regulates Aortic Valve Endothelial Cell Diversity and Extracellular Matrix Stratification in Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-08-2023)“…Specialized valve endothelial cell (VEC) populations are localized oriented to blood flow in developing aortic and mitral valves, but their roles in valve…”
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PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves
Published in Circulation research (01-09-2023)“…Cardiac valve disease is observed in 2.5% of the general population and 10% of the elderly people. Effective pharmacological treatments are currently not…”
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Vascular dimorphism ensured by regulated proteoglycan dynamics favors rapid umbilical artery closure at birth
Published in eLife (10-09-2020)“…The umbilical artery lumen closes rapidly at birth, preventing neonatal blood loss, whereas the umbilical vein remains patent longer. Here, analysis of…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Point Prevalence Among Asymptomatic Hospitalized Children and Subsequent Healthcare Worker Evaluation
Published in Journal of the Pediatric Infectious Diseases Society (10-11-2020)“…Asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) carriage among hospitalized children and risk of transmission to healthcare workers…”
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APOE-NOTCH axis governs elastogenesis during human cardiac valve remodeling
Published in Nature cardiovascular research (01-08-2024)“…Valve remodeling is a process involving extracellular matrix organization and elongation of valve leaflets. Here, through single-cell RNA sequencing of human…”
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8
Design of Artificial Red Blood Cells using Polymeric Hydrogel Microcapsules: Hydrogel Stability Improvement and Polymer Selection
Published in International journal of artificial organs (01-10-2016)“…Purpose To improve the stability of pectin-oligochitosan hydrogel microcapsules under physiological conditions. Methods Two different approaches were examined:…”
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Assessment of Fractional Flow Reserve in Patients With Recent Non–ST-Segment–Elevation Myocardial Infarction: Comparative Study With 3-T Stress Perfusion Cardiac Magnetic Resonance Imaging
Published in Circulation. Cardiovascular interventions (01-08-2015)“…BACKGROUND—The use of fractional flow reserve (FFR) in acute coronary syndromes is controversial. The British Heart Foundation Fractional Flow Reserve Versus…”
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Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST segment elevation myocardial infarction (FAMOUS-NSTEMI) developmental trial: cost-effectiveness using a mixed trial- and model-based methods
Published in Cost effectiveness and resource allocation (14-11-2015)“…In the Fractional flow reserve (FFR) versus angiography in guiding management to optimise outcomes in non-ST elevation myocardial infarction (FAMOUS) clinical…”
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Diagnostic Accuracy of 3.0-T Magnetic Resonance T1 and T2 Mapping and T2-Weighted Dark-Blood Imaging for the Infarct-Related Coronary Artery in Non-ST-Segment Elevation Myocardial Infarction
Published in Journal of the American Heart Association (01-04-2017)“…Patients with recent non-ST-segment elevation myocardial infarction commonly have heterogeneous characteristics that may be challenging to assess clinically…”
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FRACTIONAL FLOW RESERVE (FFR) VERSUS ANGIOGRAPHY IN GUIDING MANAGEMENT TO OPTIMIZE OUTCOMES IN NON-ST ELEVATION MYOCARDIAL INFARCTION (FAMOUS - NSTEMI) HEALTH ECONOMIC ANALYSIS
Published in Journal of the American College of Cardiology (17-03-2015)“…Background: An economic model was developed to compare the medical resource cost and health outcome effects of physiology-guided management with FFR compared…”
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Secreted metalloproteases ADAMTS9 and ADAMTS20 have a non-canonical role in ciliary vesicle growth during ciliogenesis
Published in Nature communications (27-02-2019)“…Although hundreds of cytosolic or transmembrane molecules form the primary cilium, few secreted molecules are known to contribute to ciliogenesis. Here,…”
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To EndoMT or Not to EndoMT: Zebrafish Heart Valve Development
Published in Circulation research (10-04-2020)Get full text
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15
Post-discharge Cleaning Evaluation of High-touch Environmental Surfaces: A Stepping Stone in Advancing Cleaning Practices
Published in American journal of infection control (01-06-2014)“…Appropriate environmental infection prevention practices by all healthcare workers are important in maintaining a safe environment for patients, visitors and…”
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Reducing the Frequency of Immediate Use Steam Sterilization: A Strategic and Collaborative Approach
Published in American journal of infection control (01-06-2014)“…Immediate use steam sterilization (IUSS), previously called flash sterilization, may be associated with increased risk of surgical infection. Best practice…”
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Do Hospital-Associated Infection Rates Really Tell the Full Story?
Published in American journal of infection control (01-06-2014)“…When catheter-associated urinary tract infection (CAUTI) surveillance began in the Pediatric Intensive Care Unit (PICU) in September 2010, the CAUTI rate was…”
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Prox1+ Endothelial Cells in Heart Valve Development and Homeostasis
Published in The FASEB journal (01-05-2021)“…Heart valve malformations are commonly found in congenital heart defects and acquired valve disease affects 2.5% of the U.S. population. As blood circulates…”
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Stewardship of Personal Protective Equipment (PPE) During a Pandemic
Published in American journal of infection control (01-07-2022)Get full text
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Stewardship of personal protective equipment (PPE): An important pandemic resource for PPE preservation and education
Published in Infection control and hospital epidemiology (01-05-2021)“…List of Procedures Based on Risk for Aerosol Generation Risk Procedure Low-risk AGP Nasopharyngeal/oropharyngeal sample collection Metered-dose inhaler…”
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