Search Results - "O'Donnell, A."
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Capturing heterogeneity in PDX models: representation matters
Published in Nature communications (31-05-2024)“…Patient derived tumor xenografts (PDXs) are important models for pre-clinical testing in cancer research and personalized medicine. PDXs often represent…”
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2
Global lake thermal regions shift under climate change
Published in Nature communications (06-03-2020)“…Water temperature is critical for the ecology of lakes. However, the ability to predict its spatial and seasonal variation is constrained by the lack of a…”
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3
Navigating the Treacherous Waters of Bacillus Calmette-Guérin Failure
Published in The Journal of urology (01-01-2023)Get full text
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4
Enterochromaffin Cells Are Gut Chemosensors that Couple to Sensory Neural Pathways
Published in Cell (29-06-2017)“…Dietary, microbial, and inflammatory factors modulate the gut-brain axis and influence physiological processes ranging from metabolism to cognition. The gut…”
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In Primary Frozen Shoulder, Arthroscopic Capsular Release Improved Function and Reduced Pain Compared with Manipulation Under Anesthesia or Early Physiotherapy with Steroid Injection at 1 Year, but Changes Were Not Clinically Important
Published in Journal of bone and joint surgery. American volume (18-08-2021)Get full text
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Racial/ethnic differences in parenting behaviors as protective factors in adolescent internalizing problems
Published in The Journal of general psychology (02-10-2023)“…The current study explores variations among racially/ethnically diverse adolescents regarding parents' role in mitigating internalizing problems. Adolescents…”
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7
Critical Assessment of Analytical Methods for the Harmonized and Cost-Efficient Analysis of Microplastics
Published in Applied spectroscopy (01-09-2020)“…Microplastics are of major concerns for society and is currently in the focus of legislators and administrations. A small number of measures to reduce or…”
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Advances in functional genetic screening with transposons and CRISPR/Cas9 to illuminate cancer biology
Published in Current opinion in genetics & development (01-04-2018)“…Large-scale genome sequencing studies have identified a wealth of mutations in human tumors and have dramatically advanced the field of cancer genetics…”
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9
A Role for Retrotransposon LINE-1 in Fetal Oocyte Attrition in Mice
Published in Developmental cell (09-06-2014)“…Fetal oocyte attrition (FOA) is a conserved but poorly understood process of elimination of more than two-thirds of meiotic prophase I (MPI) oocytes before…”
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The effect of socioeconomic deprivation on the association between an extended measurement of unhealthy lifestyle factors and health outcomes: a prospective analysis of the UK Biobank cohort
Published in The Lancet. Public health (01-12-2018)“…Combinations of lifestyle factors interact to increase mortality. Combinations of traditional factors such as smoking and alcohol are well described, but the…”
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A qualitative systematic review of studies using the normalization process theory to research implementation processes
Published in Implementation science : IS (02-01-2014)“…There is a well-recognized need for greater use of theory to address research translational gaps. Normalization Process Theory (NPT) provides a set of…”
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12
Finding the 'right' GP: a qualitative study of the experiences of people with long-COVID
Published in BJGP open (01-12-2020)“…An unknown proportion of people who had an apparently mild COVID-19 infection continue to suffer with persistent symptoms, including chest pain, shortness of…”
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13
Estimated stocks of circumpolar permafrost carbon with quantified uncertainty ranges and identified data gaps
Published in Biogeosciences (01-12-2014)“…Soils and other unconsolidated deposits in the northern circumpolar permafrost region store large amounts of soil organic carbon (SOC). This SOC is potentially…”
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14
A Conserved Splicing Silencer Dynamically Regulates O-GlcNAc Transferase Intron Retention and O-GlcNAc Homeostasis
Published in Cell reports (Cambridge) (01-08-2017)“…Modification of nucleocytoplasmic proteins with O-GlcNAc regulates a wide variety of cellular processes and has been linked to human diseases. The enzymes…”
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15
ADHD and Exposure to Maltreatment in Children and Youth: a Systematic Review of the Past 10 Years
Published in Current psychiatry reports (08-11-2020)“…Purpose of the Review The purpose of the current paper was to review and summarize the literature on ADHD and maltreatment over the past 10 years. Recent…”
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What Is the Clinical Benefit of Common Orthopaedic Procedures as Assessed by the PROMIS Versus Other Validated Outcomes Tools?
Published in Clinical orthopaedics and related research (01-09-2022)“…Patient-reported outcome measures (PROMs), including the Patient-reported Outcomes Measurement Information System (PROMIS), are increasingly used to measure…”
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A fast and accessible methodology for micro-patterning cells on standard culture substrates using Parafilm™ inserts
Published in PloS one (07-06-2011)“…Micropatterning techniques provide direct control over the spatial organization of cells at the sub-mm scale. Regulation of these spatial parameters is…”
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Intravesical nadofaragene firadenovec gene therapy for BCG-unresponsive non-muscle-invasive bladder cancer: a single-arm, open-label, repeat-dose clinical trial
Published in The lancet oncology (01-01-2021)“…BCG is the most effective therapy for high-risk non-muscle-invasive bladder cancer. Nadofaragene firadenovec (also known as rAd-IFNa/Syn3) is a…”
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The Role of Bacillus Calmette-Guérin in the Treatment of Non–Muscle-Invasive Bladder Cancer
Published in European urology (01-03-2010)“…Abstract Context Bacillus Calmette-Guérin (BCG) remains the most effective intravesical treatment for non–muscle-invasive bladder cancer (NMIBC), but the…”
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Associations of the Mediterranean-Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay diet with cardiac remodelling in the community: the Framingham Heart Study
Published in British journal of nutrition (28-12-2021)“…Normal cardiac function is directly associated with the maintenance of cerebrovascular health. Whether the Mediterranean-Dietary Approaches to Stop…”
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