Search Results - "O'Doherty, A"

Exposure of bovine oocytes and embryos to elevated non-esterified fatty acid concentrations: integration of epigenetic and transcriptomic signatures in resultant blastocysts by Desmet, K L J, Van Hoeck, V, Gagné, D, Fournier, E, Thakur, A, O'Doherty, A M, Walsh, C P, Sirard, M A, Bols, P E J, Leroy, J L M R

“…Metabolic stress associated with negative energy balance in high producing dairy cattle and obesity in women is a risk factor for decreased fertility…”
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Systematic development and feasibility testing of a multibehavioural digital prehabilitation intervention for patients approaching major surgery (iPREPWELL): A study protocol by Durrand, J, Livingston, R, Tew, G, Gillis, C, Yates, D, Gray, J, Greaves, C, Moore, J, O'Doherty, A F, Doherty, P, Danjoux, G, Avery, L

“…Improving outcomes for people undergoing major surgery, specifically reducing perioperative morbidity and mortality remains a global health challenge…”
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De Novo Asymmetric Synthesis of Anthrax Tetrasaccharide and Related Tetrasaccharide by Guo, Haibing, O’Doherty, George A

“…A de novo asymmetric approach to the natural product anthrax tetrasaccharide 1 and an analogue 2 with an anomeric hexyl azide group has been developed from…”
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Development of a RSK Inhibitor as a Novel Therapy for Triple-Negative Breast Cancer by Ludwik, Katarzyna A, Campbell, J Preston, Li, Mingzong, Li, Yu, Sandusky, Zachary M, Pasic, Lejla, Sowder, Miranda E, Brenin, David R, Pietenpol, Jennifer A, O'Doherty, George A, Lannigan, Deborah A

“…Metastatic breast cancer is an incurable disease and identification of novel therapeutic opportunities is vital. Triple-negative breast cancer (TNBC)…”
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Synthesis and biological study of the phomopsolide and phomopsolidone natural products by Aljahdali, Alhanouf Z, Foster, Kathryn A, O'Doherty, George A

“…The complete history of the syntheses and biological activities of the phomopsolide and phomopsolidone classes of natural products is reviewed. These efforts…”
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Preoperative aerobic exercise training in elective intra-cavity surgery: a systematic review by O'Doherty, A.F., West, M., Jack, S., Grocott, M.P.W.

“…Reduced physical fitness is associated with increased risk of complications after intra-cavity surgery. Aerobic exercise training interventions improve…”
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Lipopolysaccharide (LPS) disrupts particle transport, cilia function and sperm motility in an ex vivo oviduct model by O’Doherty, A. M., Di Fenza, M., Kölle, S.

“…The oviduct functions in the transportation of gametes to the site of fertilization (the ampulla) and is the site of early embryonic development. Alterations…”
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Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study by Azalim, Pedro, do Monte, Fernando M., Rendeiro, Mariana Manzano, Liu, Xiaofan, O'Doherty, George A., Fontes, Carlos Frederico, Leitão, Suzana Guimarães, Quintas, Luis Eduardo M., Noël, François

“…[Display omitted] There is a renewed interest in the Na+/K+-ATPase (NKA, EC 3.6.3.9) either as a target for new therapeutic uses or for understanding the…”
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De Novo Asymmetric Synthesis of the Anthrax Tetrasaccharide by a Palladium-Catalyzed Glycosylation Reaction by Guo, Haibing, O'Doherty, George A.

“…Choose your poison: In the de novo asymmetric synthesis of the anthrax tetrasaccharide 1 (25 steps from acetylfuran), the absolute configurations of three L…”
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The approach to an isolated close anterior margin in breast conserving surgery by O'Connell, L, Walsh, S, Evoy, D, O'Doherty, A, Quinn, C, Rothwell, J, Geraghty, J, McDermott, E W, Prichard, R

“…Although close radial margins after breast-conserving surgery routinely undergo re-excision, appropriate management of patients with close anterior margins…”
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A Palladium-Catalyzed Glycosylation Reaction:  The de Novo Synthesis of Natural and Unnatural Glycosides by Babu, Ravula Satheesh, O'Doherty, George A

“…A highly stereoselective and sterospecific palladium-catalyzed glycosylation reaction of a variety of alcohols is reported. The reaction selectively converts…”
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Cardiopulmonary exercise testing predicts postoperative outcome in patients undergoing gastric bypass surgery by Hennis, P.J., Meale, P.M., Hurst, R.A., O’Doherty, A.F., Otto, J., Kuper, M., Harper, N., Sufi, P.A., Heath, D., Montgomery, H.E., Grocott, M.P.W.

“…For several types of non-cardiac surgery, the cardiopulmonary exercise testing (CPET)-derived variables anaerobic threshold (AT), peak oxygen consumption (…”
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De Novo Synthesis of Oligosaccharides Using a Palladium-Catalyzed Glycosylation Reaction by Babu, Ravula Satheesh, Zhou, Maoquan, O'Doherty, George A

“…The natural all d- and/or unnatural all l-1,4- and 1,6-oligosaccharides were synthesized from furan alcohols using a palladium-catalyzed glycosylation…”
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Correlation of needle core biopsy with excision histology in screen-detected B3 lesions: the Merrion Breast Screening Unit experience by Hayes, B D, O'Doherty, A, Quinn, C M

“…Needle core biopsy (NCB) is a widely-used technique for non-operative evaluation of screen-detected breast lesions. Although most NCBs are B2 (benign) or B5…”
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A Practical Synthesis of Glycinamide Ribonucleotide by A. O'Doherty, George, J. Beuning, Penny, Jo Ondrechen, Mary, Ray, Debarpita

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Development and characterisation of a novel rat model of Parkinson's disease induced by sequential intranigral administration of AAV-α-synuclein and the pesticide, rotenone by Mulcahy, P, O'Doherty, A, Paucard, A, O'Brien, T, Kirik, D, Dowd, E

“…Abstract Modeling Parkinson's disease remains a major challenge for preclinical researchers, as existing models fail to reliably recapitulate all of the…”
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Prevalence and Characteristics of Breakthrough Pain in Cancer Patients Admitted to a Hospice by Zeppetella, Giovambattista, O'Doherty, Catherine A, Collins, Silke

“…A prospective survey was undertaken to determine the prevalence and characteristics of breakthrough pain in cancer patients admitted to a hospice. Of 414…”
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Epigenetic reprogramming during spermatogenesis and male factor infertility by McSwiggin, H M, O’Doherty, A M

“…Infertility is an often devastating diagnosis encountered by around one in six couples who are trying to conceive. Moving away from the long-held belief that…”
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Axillary nodal burden in primary breast cancer patients with positive pre-operative ultrasound guided fine needle aspiration cytology: Management in the era of ACOSOG Z011 by Boland, M.R, Prichard, R.S, Daskalova, I, Lowery, A.J, Evoy, D, Geraghty, J, Rothwell, J, Quinn, C.M, O'Doherty, A, McDermott, E.W

“…Abstract Introduction Recent years have seen a dramatic shift to more conservative management of the axilla in patients with a positive sentinel lymph node…”
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Structure-activity relationship of avocadyne by Tcheng, Matthew, Cunha, Vitor L S, Ahmed, Nawaz, Liu, Xiaofan, Smith, Richard W, Rea, Kevin A, Akhtar, Tariq A, D'Alessandro, Angelo, Minden, Mark D, Vockley, Jerry, O'Doherty, George A, Lowary, Todd L, Spagnuolo, Paul A

“…Avocado consumption is associated with numerous health benefits. Avocadyne is a terminally unsaturated, 17-carbon long acetogenin found almost exclusively in…”
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