Search Results - "O'Dell, David K."

Identification of Farnesyl Pyrophosphate and N-Arachidonylglycine as Endogenous Ligands for GPR92 by Oh, Da Young, Yoon, Jung Min, Moon, Mi Jin, Hwang, Jong-Ik, Choe, Han, Lee, Ju Yeon, Kim, Jae Il, Kim, Sunoh, Rhim, Hyewhon, O'Dell, David K., Walker, J. Michael, Na, Heung Sik, Lee, Min Goo, Kwon, Hyuk Bang, Kim, Kyungjin, Seong, Jae Young

“…A series of small compounds acting at the orphan G protein-coupled receptor GPR92 were screened using a signaling pathway-specific reporter assay system…”
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Synthesis of 3-Substituted Quinolines via Transition-Metal-Catalyzed Reductive Cyclization of o-Nitro Baylis−Hillman Acetates by O'Del, David K, Nicholas, Kenneth M

“…Reductive cyclization of o-nitro-substituted Baylis−Hillman acetates by carbon monoxide, catalyzed by [Cp*Fe(CO)2]2, gives moderate to good yields of…”
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Unexpected products from the Fp2-catalyzed reductive cyclization of nitroaromatics bearing pendant unsaturation by O'Dell, David K, Nicholas, Kenneth M

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Identification of endogenous acyl amino acids based on a targeted lipidomics approach by Tan, Bo, O'Dell, David K, Yu, Y. William, Monn, M. Francesca, Hughes, H. Velocity, Burstein, Sumner, Walker, J. Michael

“…Using a partially purified bovine brain extract, our lab identified three novel endogenous acyl amino acids in mammalian tissues. The presence of numerous…”
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Synthesis of 1H-Indazoles by Reductive Cyclization of o-Nitro-ketoximes by M. Nicholas, Kenneth, K. O'Dell, David

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The endocannabinoid anandamide is a precursor for the signaling lipid N-arachidonoyl glycine by two distinct pathways by Bradshaw, Heather B, Rimmerman, Neta, Hu, Sherry Shu-Jung, Benton, Valery M, Stuart, Jordyn M, Masuda, Kim, Cravatt, Benjamin F, O'Dell, David K, Walker, J Michael

“…N-arachidonoyl glycine (NAGly) is an endogenous signaling lipid with a wide variety of biological activity whose biosynthesis is poorly understood. Two primary…”
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N-palmitoyl glycine, a novel endogenous lipid that acts as a modulator of calcium influx and nitric oxide production in sensory neurons by Rimmerman, Neta, Bradshaw, Heather B, Hughes, H Velocity, Chen, Jay Shih-Chieh, Hu, Sherry Shu-Jung, McHugh, Douglas, Vefring, Eivind, Jahnsen, Jan A, Thompson, Eric L, Masuda, Kim, Cravatt, Benjamin F, Burstein, Sumner, Vasko, Michael R, Prieto, Anne L, O'Dell, David K, Walker, J Michael

“…N-arachidonoyl glycine is an endogenous arachidonoyl amide that activates the orphan G protein-coupled receptor (GPCR) GPR18 in a pertussis toxin…”
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Targeted lipidomics approach for endogenous N-acyl amino acids in rat brain tissue by Tan, Bo, William Yu, Y., Francesca Monn, M., Velocity Hughes, H., O’Dell, David K., Michael Walker, J.

“…Great effort has been devoted to characterize signaling lipids in central nervous system. This has led to a search for novel strategies to characterize…”
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Structural analysis of leukotriene C4 isomers using collisional activation and 157 nm photodissociation by Devakumar, Arugadoss, O’Dell, David K., Walker, J. Michael, Reilly, James P.

“…The fragmentation of 5-hydroxy-6-glutathionyl-7,9,11,14-eicosatetraenoic acid [leukotriene C 4 or LTC 4 (5, 6)] and its isomeric counterpart LTC 4 (14, 15)…”
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Alcohol dehydrogenase-catalyzed in vitro oxidation of anandamide to N-arachidonoyl glycine, a lipid mediator: Synthesis of N-acyl glycinals by Aneetha, Halikhedkar, O’Dell, David K., Tan, Bo, Walker, J. Michael, Hurley, Thomas D.

“…Human alcohol dehydrogenase-catalyzed metabolism of endocannabinoid anandamide to N-arachidonoyl glycinal and N-arachidonoyl glycine and a straightforward…”
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Fatty acyl amides of endogenous tetrahydroisoquinolines are active at the recombinant human TRPV1 receptor by O’Dell, David K., Rimmerman, Neta, Pickens, Sarah R., Walker, J. Michael

“…The SAR of capsazepine revealed that tetrahydroisoquinoline (TIQ) moiety is a core pharmacophore of TRPV1 activity. This implied that conjugates of endogenous…”
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Identification of endogenous acyl amino acids based on a targeted lipidomics approach1[S] by Tan, Bo, O’Dell, David K., Yu, Y. William, Monn, M. Francesca, Hughes, H. Velocity, Burstein, Sumner, Walker, J. Michael

“…Using a partially purified bovine brain extract, our lab identified three novel endogenous acyl amino acids in mammalian tissues. The presence of numerous…”
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Profiling of phospholipids and related lipid structures using multidimensional ion mobility spectrometry-mass spectrometry by Trimpin, Sarah, Tan, Bo, Bohrer, Brian C., O’Dell, David K., Merenbloom, Samuel I., Pazos, Mauricio X., Clemmer, David E., Walker, J. Michael

“…Increasingly comprehensive questions related to the biosynthesis of lipids relevant to understanding new signaling pathways have created daunting tasks for…”
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Structural Analysis of Leukotriene C 4 Isomers Using Collisional Activation and 157 nm Photodissociation by Devakumar, Arugadoss, O’Dell, David K., Walker, J. Michael, Reilly, James P.

“…The fragmentation of 5-hydroxy-6-glutathionyl-7,9,11,14-eicosatetraenoic acid [leukotriene C 4 or LTC 4 (5, 6)] and its isomeric counterpart LTC 4 (14, 15)…”
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Targeted lipidomics approach for endogenous N-acyl amino acids in rat brain tissue: LIPIDOMICS: DEVELOPMENTS AND APPLICATIONS by BO TAN, YU, Y. William, MONN, M. Francesca, HUGHES, H. Velocity, O'DELL, David K, WALKER, J. Michael

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Unexpected products from the Fp 2-catalyzed reductive cyclization of nitroaromatics bearing pendant unsaturation by O'Dell, David K, Nicholas, Kenneth M

“…A representative o-nitroenone (Z=O) was cyclized by reduction with CO and [CpFe(CO) 2] 2 (Fp 2) as the catalyst to give the corresponding 4-quinolone. In…”
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Identification of Farnesyl Pyrophosphate and N-Arachidonylglycine as Endogenous Ligands for GPR92S by Oh, Da Young, Yoon, Jung Min, Moon, Mi Jin, Hwang, Jong-Ik, Choe, Han, Lee, Ju Yeon, Kim, Jae Il, Kim, Sunoh, Rhim, Hyewhon, O'Dell, David K., Walker, J. Michael, Na, Heung Sik, Lee, Min Goo, Kwon, Hyuk Bang, Kim, Kyungjin, Seong, Jae Young

“…A series of small compounds acting at the orphan G protein-coupled receptor GPR92 were screened using a signaling pathway-specific reporter assay system…”
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Synthesis of nitrogen heterocycles via transition metal catalyzed reductive cyclizations of nitroaromatics by O'Dell, David K

“…This research focuses on applying a catalyst system discovered in this laboratory, for the intermolecular allylic amination of alkenes with nitrobenzenes, to…”
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Synthesis of nitrogen heterocycles via transition metal catalyzed reductive cyclizations of nitroaromatics by O'Dell, David K

“…This research focuses on applying a catalyst system discovered in this laboratory, for the intermolecular allylic amination of alkenes with nitrobenzenes, to…”
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