Search Results - "O'DONNELL, J"
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Fetal Origins of Mental Health: The Developmental Origins of Health and Disease Hypothesis
Published in The American journal of psychiatry (01-04-2017)“…The quality of fetal growth and development predicts the risk for a range of noncommunicable, chronic illnesses. These observations form the basis of the…”
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Prescription Fill Patterns for Commonly Used Drugs During the COVID-19 Pandemic in the United States
Published in JAMA : the journal of the American Medical Association (23-06-2020)“…This pharmacoepidemiology study uses US pharmacy data to compare prescriptions for hydroxychloroquine/chloroquine and azithromycin in February to April 2020 vs…”
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Prolonged Infusion Piperacillin-Tazobactam Decreases Mortality and Improves Outcomes in Severely Ill Patients: Results of a Systematic Review and Meta-Analysis
Published in Critical care medicine (01-02-2018)“…OBJECTIVE:Piperacillin-tazobactam is a commonly used antibiotic in critically ill patients; however, controversy exists as to whether mortality in serious…”
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New Perspectives on Antimicrobial Agents: Imipenem-Relebactam
Published in Antimicrobial agents and chemotherapy (19-07-2022)“…Imipenem (IMI)/cilastatin/relebactam (REL) (I/R) is a novel β-lactam/β-lactamase inhibitor combination with expanded microbiologic activity against…”
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Enhanced Redox State and Efficiency of Glucose Oxidation With miR Based Suppression of Maladaptive NADPH-Dependent Malic Enzyme 1 Expression in Hypertrophied Hearts
Published in Circulation research (16-03-2018)“…RATIONALE:Metabolic remodeling in hypertrophic hearts includes inefficient glucose oxidation via increased anaplerosis fueled by pyruvate carboxylation…”
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Rural-Urban Differences in Cardiovascular Mortality in the US, 1999-2017
Published in JAMA : the journal of the American Medical Association (12-05-2020)“…This study used data from the US Centers for Disease Control and Prevention WONDER database to examined temporal trends in cardiovascular disease age-adjusted…”
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Expert assessment of vulnerability of permafrost carbon to climate change
Published in Climatic change (01-07-2013)“…Approximately 1700 Pg of soil carbon (C) are stored in the northern circumpolar permafrost zone, more than twice as much C than in the atmosphere. The overall…”
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GRASP: analysis of genotype-phenotype results from 1390 genome-wide association studies and corresponding open access database
Published in Bioinformatics (Oxford, England) (15-06-2014)“…We created a deeply extracted and annotated database of genome-wide association studies (GWAS) results. GRASP v1.0 contains >6.2 million SNP-phenotype…”
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Polygenic Risk Scores for Cardiovascular Disease: A Scientific Statement From the American Heart Association
Published in Circulation (New York, N.Y.) (23-08-2022)“…Cardiovascular disease is the leading contributor to years lost due to disability or premature death among adults. Current efforts focus on risk prediction and…”
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Impact of Accelerate Pheno and BacT/Alert Virtuo on Clinical Processes and Outcomes in Patients with Sepsis and Concurrent Gram-Negative Bacteremia
Published in Antimicrobial agents and chemotherapy (18-05-2021)“…The Accelerate Pheno and BacT/Alert Virtuo systems may improve bacteremia management. Here, we evaluated the impact of both devices on outcomes in patients…”
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The persisting effect of maternal mood in pregnancy on childhood psychopathology
Published in Development and psychopathology (01-05-2014)“…Developmental or fetal programming has emerged as a major model for understanding the early and persisting effects of prenatal exposures on the health and…”
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Universality and diversity in human song
Published in Science (American Association for the Advancement of Science) (22-11-2019)“…What is universal about music, and what varies? We built a corpus of ethnographic text on musical behavior from a representative sample of the world's…”
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A perspective on insect water balance
Published in Journal of experimental biology (01-04-2022)“…Insects have a large ratio of surface area to volume because of their small size; thus, they face the potential for desiccation in the terrestrial environment…”
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Synthetic Approaches to the New Drugs Approved During 2015
Published in Journal of medicinal chemistry (10-08-2017)“…New drugs introduced to the market every year represent privileged structures for particular biological targets. These new chemical entities (NCEs) provide…”
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Assessment of dispersion of airborne particles of oral/nasal fluid by high flow nasal cannula therapy
Published in PloS one (12-02-2021)“…Nasal High Flow (NHF) therapy delivers flows of heated humidified gases up to 60 LPM (litres per minute) via a nasal cannula. Particles of oral/nasal fluid…”
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A new look at the decomposition of agricultural productivity growth incorporating weather effects
Published in PloS one (21-02-2018)“…Random fluctuations in temperature and precipitation have substantial impacts on agricultural output. However, the contribution of these changing…”
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Hypertension and Cognitive Impairment: A Review of Mechanisms and Key Concepts
Published in Frontiers in neurology (04-02-2022)“…Cognitive impairment, and dementia, are major contributors to global burden of death and disability, with projected increases in prevalence in all regions of…”
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Gap junction protein connexin43 exacerbates lung vascular permeability
Published in PloS one (26-06-2014)“…Increased vascular permeability causes pulmonary edema that impairs arterial oxygenation and thus contributes to morbidity and mortality associated with Acute…”
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Fetal Programming and Public Policy
Published in Journal of the American Academy of Child and Adolescent Psychiatry (01-06-2023)“…Fetal programming is a core concept within the broader developmental origins of health and disease framework, which acknowledges the contribution of the…”
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The heterodimeric glycoprotein hormone, GPA2/GPB5, regulates ion transport across the hindgut of the adult mosquito, Aedes aegypti
Published in PloS one (20-01-2014)“…A family of evolutionarily old hormones is the glycoprotein cysteine knot-forming heterodimers consisting of alpha- (GPA) and beta-subunits (GPB), which…”
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