Search Results - "O'Connor, Juan"

Third- or Later-line Therapy for Metastatic Colorectal Cancer: Reviewing Best Practice by Bekaii-Saab, Tanios, Kim, Richard, Kim, Tae Won, O’Connor, Juan Manuel, Strickler, John H., Malka, David, Sartore-Bianchi, Andrea, Bi, Feng, Yamaguchi, Kensei, Yoshino, Takayuki, Prager, Gerald W.

“…An increasing number of patients with metastatic colorectal cancer (mCRC) are able to receive 3 or more lines of therapy. Treatments in this setting can…”
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Safety and effectiveness of regorafenib in patients with metastatic colorectal cancer in routine clinical practice in the prospective, observational CORRELATE study by Ducreux, Michel, Petersen, Lone Nørgård, Öhler, Leopold, Bergamo, Francesca, Metges, Jean-Philippe, de Groot, Jan Willem, Wang, Jaw-Yuan, García Paredes, Beatriz, Dochy, Emmanuelle, Fiala-Buskies, Sabine, Cervantes, Andrés, O'Connor, Juan Manuel, Falcone, Alfredo

“…Regorafenib prolonged overall survival (OS) versus placebo in patients with treatment-refractory metastatic colorectal cancer (mCRC) in phase III trials. We…”
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ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms of the digestive system: well-differentiated pancreatic non-functioning tumors by Falconi, Massimo, Bartsch, Detlef Klaus, Eriksson, Barbro, Klöppel, Günter, Lopes, José M, O'Connor, Juan M, Salazar, Ramón, Taal, Babs G, Vullierme, Marie Pierre, O'Toole, Dermot

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Metastatic pheochromocytoma and paraganglioma: a retrospective multicentre analysis on prognostic and predictive factors to chemotherapy by Pacheco, Samara T, Donadio, Mauro D, Almeida, Felipe, O'Connor, Juan M, de Miguel, Valeria, Dioca, Mariano, Huaman, Jose, Bragagnoli, Arinilda C, Weschenfelder, Rui F, Beltran, Paola M, Riechelmann, Rachel P

“…Prognostic and predictive markers in metastatic pheochromocytoma and paraganglioma (mPPGL) are unknown. We aimed to evaluate epidemiology of mPPGL, and…”
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Administration of the vasopressin analog desmopressin for the management of bleeding in rectal cancer patients: results of a phase I/II trial by Iseas, Soledad, Roca, Enrique L., O’Connor, Juan M., Eleta, Martin, Sanchez-Luceros, Analia, Di Leo, Daniela, Tinelli, Marcelo, Fara, Maria L., Spitzer, Eduardo, Demarco, Ignacio A., Ripoll, Giselle V., Pifano, Marina, Garona, Juan, Alonso, Daniel F.

“…Summary Purpose The vasopressin analog desmopressin (dDAVP) is known to increase plasma levels of hemostatic factors, and preclinical studies in colorectal…”
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The LEGACy study: a European and Latin American consortium to identify risk factors and molecular phenotypes in gastric cancer to improve prevention strategies and personalized clinical decision making globally by van Schooten, Tessa Suzanne, Derks, Sarah, Jiménez-Martí, Elena, Carneiro, Fatima, Figueiredo, Ceu, Ruiz, Erika, Alsina, Maria, Molero, Cristina, Garrido, Marcelo, Riquelme, Arnoldo, Caballero, Carmelo, Lezcano, Eva, O'Connor, Juan Manuel, Esteso, Federico, Farrés, Judith, Mas, José Manuel, Lordick, Florian, Vogt, Jeannette, Cardone, Antonella, Girvalaki, Charis, Cervantes, Andrés, Fleitas, Tania

“…Gastric Cancer (GC) is the fourth most deadly cancer worldwide. Enhanced understanding of its key epidemiological and molecular drivers is urgently needed to…”
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Liquid biopsy for KRAS, NRAS and BRAF mutation testing in advanced colorectal cancer patients: the Argentinean experience by Güttlein, Leandro, Luca, María R, Esteso, Federico, Fresno, Cristóbal, Mariani, Javier, Otero Pizarro, Mercedes, Brest, Esteban, Starapoli, Solange, Kreimberg, Kevin, Teves, Paula, Mendoza Bertelli, Andrea, R Girotti, María, Salanova, Ruben, O’Connor, Juan M

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Phase II Study of Adjuvant Immunotherapy with the CSF-470 Vaccine Plus Bacillus Calmette-Guerin Plus Recombinant Human Granulocyte Macrophage-Colony Stimulating Factor vs Medium-Dose Interferon Alpha 2B in Stages IIB, IIC, and III Cutaneous Melanoma Patients: A Single Institution, Randomized Study by Mordoh, José, Pampena, María Betina, Aris, Mariana, Blanco, Paula Alejandra, Lombardo, Mónica, von Euw, Erika María, Mac Keon, Soledad, Yépez Crow, Michelle, Bravo, Alicia Inés, O'Connor, Juan Manuel, Orlando, Ana Gabriela, Ramello, Franco, Levy, Estrella Mariel, Barrio, María Marcela

“…The irradiated, allogeneic, cellular CSF-470 vaccine plus Bacillus Calmette-Guerin (BCG) and recombinant human granulocyte macrophage-colony stimulating factor…”
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Atypical pattern of response in rectal cancer after neoadjuvant pembrolizumab treatment: a case report, literature review, and proposed management model by Tissera, Natalia S, Esteso, Federico, Luca, Romina, Enrico, Diego, Waisberg, Federico, Rodriguez, Andrés, Bruno, Luisina, Kucharczyk, Mariana, Amat, Mora, García, Ximena, Pombo, Teresa, Salazar, Ivana Pedraza, Loria, Fernando Sanchez, Huertas, Eduardo, Galli, Mariana, Chacón, Matías, O'Connor, Juan Manuel

“…Immunotherapy is the first-line treatment in patients with advanced microsatellite instability-high (MSI-H) or deficient mismatch repair (dMMR) colorectal…”
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Multidisciplinary approach to COVID-19 and cancer: consensus from scientific societies in Argentina by Ismael, Julia, Losco, Federico, Quildrian, Sergio, Sanchez, Pablo, Pincemin, Isabel, Lastiri, Jose, Bella, Santiago, Chinellato, Alejandro, Dellamea, Guillermo, Ahualli, Alejandro, Rompato, Silvana, Velez, Julio, Escobar, Rafael, Zwenger, Ariel, Rosales, Cristina, Bagnes, Claudia, Puyol, Jorge, Niewiadomski, Dario, Smecuol, Edgardo, Nachman, Fabio, Gonzalez, Eduardo, Ferraris, Gustavo, Suppicich, Juan Ramos, Price, Paola, Medina, Luis, O'Connor, Juan

“…The world is living through an outbreak of an acute respiratory syndrome caused by a new betacoronavirus known as coronavirus 2 (SARS CoV-2), which has been…”
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Opportunistic and Serious Infections in Patients with Neuroendocrine Tumors Treated with Everolimus: A Multicenter Study of Real-World Patients by Mauro, Carine, de Jesus, Victor Hugo Fonseca, Barros, Milton, Costa, Frederico Perego, Weschenfelder, Rui F, D'Agustini, Nathalia, Angel, Martin, Luca, Romina, Nuñez, Jose Eduardo, O'Connor, Juan Manuel, Riechelmann, Rachel P

“…The incidence of infections is poorly studied in patients with neuroendocrine tumors (NET) treated with everolimus outside of clinical trials. We aimed to…”
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Performance of two prognostic scores that incorporate genetic information to predict long‐term outcomes following resection of colorectal cancer liver metastases: An external validation of the MD Anderson and JHH‐MSK scores by Sasaki, Kazunari, Gagnière, Johan, Dupré, Aurélien, Ardiles, Victoria, O'Connor, Juan Manuel, Wang, Jaeyun, Moro, Amika, Morioka, Daisuke, Buettner, Stefan, Gau, Laurence, Ribeiro, Mathieu, Wagner, Doris, Andreatos, Nikolaos, Løes, Inger Marie, Fitschek, Fabian, Kaczirek, Klaus, Lønning, Per Eystein, Kornprat, Peter, Poultsides, George, Kamphues, Carsten, Imai, Katsunori, Baba, Hideo, Endo, Itaru, Kwon, Choon Hyuck David, Aucejo, Federico N., Santibañes, Eduardo, Kreis, Martin E., Margonis, Georgios Antonios

“…Introduction Two novel clinical risk scores (CRS) that incorporate KRAS mutation status were developed: modified CRS (mCRS) and GAME score. However, they have…”
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Outcomes of Patients With Metastatic Anal Cancer According to HIV Infection: A Multicenter Study by the Latin American Gastrointestinal Oncology Group (SLAGO) by Mattos, Bruna R.S., Camandaroba, Marcos P.G., Ruiz-Garcia, Erika, Diaz-Romero, Consuelo, Luca, Romina, Mendez, Guillermo, Lustosa, Iara K.F., Silva, Sinara F., Mello, Celso A., Silva, Virgilio S., O'Connor, Juan M., Riechelmann, Rachel P.

“…HIV-positive patients are underrepresented in clinical trials of metastatic squamous cell carcinoma of the anal canal (mSCCA). We aimed to compare the clinical…”
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Implementation of a virtual multicenter gastrointestinal tumor board to reduce cancer disparities in Argentina by Esteso, Federico, Tissera, Natalia Soledad, O'Connor, Juan Manuel, Luca, Romina, Huertas, Eduardo, Sánchez Loria, Fernando, Pedraza, Ivana, Pairola, Alejandro, Brancato, Fernando, Paganini, Lisandro, Kucharczyk, Mariana, Amat, Mora, Pombo, Maria Teresa, Galli, Mariana, Bruno, Luisina, Caro, Luis, Rodriguez, Andrés, Enrico, Diego, Waisberg, Federico, Chacón, Matías

“…Given the increasing complexity of cancer care, multidisciplinary tumor boards have become essential in daily clinical oncology practice. The Project Extension…”
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Prognostic impact of K-RAS mutational status and primary tumor location in patients undergoing resection for colorectal cancer liver metastases: an update by O Connor, Juan M, Sanchez Loria, Fernando, Ardiles, Victoria, Grondona, Jorge, Sanchez, Pablo, Andriani, Oscar, Fauda, Martin, Brancato, Fernando, Huertas, Eduardo, Alvarez, Fernando, de Santibañes, Eduardo

“…To determine the impact of KRAS mutation status on survival in patients undergoing surgery for colorectal liver metastases (CLM). Patients with resected CLM…”
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Health resource utilisation by patients with neuroendocrine tumours with or without carcinoid heart disease: a multinational study by Tanaka, Hugo, Uema, Deise, Rego, Juliana F M, Weschenfelder, Rui F, D'Agustini, Nathalia, Filho, Duilio R Rocha, O'Connor, Juan M, Luca, Romina, Nuñez, Jose Eduardo R, de Barros E Silva, Milton José, Riechelmann, Rachel P

“…Carcinoid heart disease (CHD) is a rare and severe complication from carcinoid syndrome which may be associated with high health resource utilisation (HRU). We…”
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Implementation of a molecular tumour board in LATAM: the impact on treatment decisions for patients evaluated at Instituto Alexander Fleming, Argentina by Angel, Martín Osvaldo, Pupareli, Carmen, Soule, Tomas, Tsou, Florencia, Leiva, Mariano, Losco, Federico, Esteso, Federico, O Connor, Juan Manuel, Luca, Romina, Petracci, Fernando, Girotti, Romina, Mahmoud, Yamil Damián, Martín, Claudio, Chacón, Matías

“…The role of the molecular tumour board (MTB) is to recommend personalised therapy for patients with cancer beyond standard-of-care treatment. A comprehensive…”
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Observational study of patients with gastroenteropancreatic and bronchial neuroendocrine tumors in Argentina: Results from the large database of a multidisciplinary group clinical multicenter study by O'CONNOR, JUAN MANUEL, MARMISSOLLE, FABIANA, BESTANI, CLAUDIA, PESCE, VERONICA, BELLI, SUSANA, DOMINICHINI, ENZO, MENDEZ, GUILLERMO, PRICE, PAOLA, GIACOMI, NORA, PAIROLA, ALEJANDRO, LORIA, FERNANDO SÁNCHEZ, HUERTAS, EDUARDO, MARTIN, CLAUDIO, PATANE, KARINA, POLERI, CLAUDIA, ROSENBERG, MOISES, CABANNE, ANA, KUJARUK, MIRTA, CAINO, ANALIA, ZAMORA, VICTOR, MARIANI, JAVIER, DIOCA, MARIANO, PARMA, PATRICIA, PODESTA, GUSTAVO, ANDRIANI, OSCAR, GONDOLESI, GABRIEL, ROCA, ENRIQUE

“…Neuroendocrine tumors (NET) include a spectrum of malignancies arising from neuroendocrine cells throughout the body. The objective of this clinical…”
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Gastrinoma (duodenal and pancreatic) by Jensen, Robert T, Niederle, Bruno, Mitry, Emmanuel, Ramage, John K, Steinmuller, Thomas, Lewington, V, Scarpa, Aldo, Sundin, Anders, Perren, Aurel, Gross, David, O'Connor, Juan M, Pauwels, Stanislas, Kloppel, Gunter

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Unmet Medical Needs in Metastatic Lung and Digestive Neuroendocrine Neoplasms by Capdevila, Jaume, Bodei, Lisa, Davies, Philippa, Gorbounova, Vera, Jensen, Robert T, Knigge, Ulrich P, Krejs, Guenter J, Krenning, Eric, O'Connor, Juan Manuel, Peeters, Marc, Rindi, Guido, Salazar, Ramon, Vullierme, Marie-Pierre, Pavel, Marianne E

“…Unmet medical needs are not infrequent in oncology, and these needs are usually of higher magnitude in rare cancers. The field of neuroendocrine neoplasms…”
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