Search Results - "O'Connell, P.J."

Islet Product Characteristics and Factors Related to Successful Human Islet Transplantation From the Collaborative Islet Transplant Registry (CITR) 1999–2010 by Balamurugan, A. N., Naziruddin, B., Lockridge, A., Tiwari, M., Loganathan, G., Takita, M., Matsumoto, S., Papas, K., Trieger, M., Rainis, H., Kin, T., Kay, T. W., Wease, S., Messinger, S., Ricordi, C., Alejandro, R., Markmann, J., Kerr‐Conti, J., Rickels, M. R., Liu, C., Zhang, X., Witkowski, P., Posselt, A., Maffi, P., Secchi, A., Berney, T., O'Connell, P. J., Hering, B. J., Barton, F. B.

“…The Collaborative Islet Transplant Registry (CITR) collects data on clinical islet isolations and transplants. This retrospective report analyzed 1017 islet…”
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Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons by Hawthorne, W. J., Salvaris, E. J., Phillips, P., Hawkes, J., Liuwantara, D., Burns, H., Barlow, H., Stewart, A. B., Peirce, S. B., Hu, M., Lew, A. M., Robson, S. C., Nottle, M. B., D'Apice, A. J. F., O'Connell, P. J., Cowan, P. J.

“…The instant blood‐mediated inflammatory reaction (IBMIR) is a major obstacle to the engraftment of intraportal pig islet xenografts in primates. Higher…”
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Multicenter Australian Trial of Islet Transplantation: Improving Accessibility and Outcomes by O'Connell, P. J., Holmes‐Walker, D. J., Goodman, D., Hawthorne, W. J., Loudovaris, T., Gunton, J. E., Thomas, H. E., Grey, S. T., Drogemuller, C. J., Ward, G. M., Torpy, D. J., Coates, P. T., Kay, T. W.

“…Whilst initial rates of insulin independence following islet transplantation are encouraging, long‐term function using the Edmonton Protocol remains a concern…”
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Transplant Glomerulopathy: Ultrastructural Abnormalities Occur Early in Longitudinal Analysis of Protocol Biopsies by Wavamunno, M. D., O'Connell, P. J., Vitalone, M., Fung, C. L.‐S., Allen, R. D. M., Chapman, J. R., Nankivell, B. J.

“…Transplant glomerulopathy (TXG) presents a distinctive pattern of glomerular abnormalities. The aim of this study was to describe its sequential…”
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Tirofiban and Activated Protein C Synergistically Inhibit the Instant Blood Mediated Inflammatory Reaction (IBMIR) from Allogeneic Islet Cells Exposure to Human Blood by Akima, S., Hawthorne, W. J., Favaloro, E., Patel, A., Blyth, K., Mudaliar, Y., Chapman, J. R., O’Connell, P. J.

“…Instant blood mediated inflammatory reaction (IBMIR) occurs when islets are exposed to blood and manifests clinically as portal vein thrombosis and graft…”
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A monoclonal antibody to CD11d reduces the inflammatory infiltrate into the injured spinal cord: a potential neuroprotective treatment by Saville, L.R., Pospisil, C.H., Mawhinney, L.A., Bao, F., Simedrea, F.C., Peters, A.A., O'Connell, P.J., Weaver, L.C., Dekaban, G.A.

“…The accumulation of inflammatory cells in the lesion of a spinal cord injury (SCI) enhances secondary damage, resulting in further neurological impairment…”
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BK Virus Nephropathy: Histological Evolution by Sequential Pathology by Nankivell, B. J., Renthawa, J., Sharma, R. N., Kable, K., O'Connell, P. J., Chapman, J. R.

“…Reactivation of BK virus in renal allografts causes a destructive chronic infection. This single‐center retrospective cohort study describes the evolution of…”
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The Role of Macrophages in the Development of Human Renal Allograft Fibrosis in the First Year After Transplantation by Toki, D., Zhang, W., Hor, K. L. M., Liuwantara, D., Alexander, S. I., Yi, Z., Sharma, R., Chapman, J. R., Nankivell, B. J., Murphy, B., O'Connell, P. J.

“…The aim of this study was to investigate the role of infiltrating macrophages in renal allograft fibrosis. Forty‐six protocol renal allograft biopsies obtained…”
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Evaluation of the Effect of Tofacitinib Exposure on Outcomes in Kidney Transplant Patients by Vincenti, F., Silva, H. T., Busque, S., O'Connell, P. J., Russ, G., Budde, K., Yoshida, A., Tortorici, M. A., Lamba, M., Lawendy, N., Wang, W., Chan, G.

“…Tofacitinib fixed‐dose regimens attained better kidney function and comparable efficacy to cyclosporine (CsA) in kidney transplant patients, albeit with…”
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The Transplantation Society Believes a Policy of Engagement Will Facilitate Organ Donation Reform in China by O'Connell, P. J., Ascher, N., Delmonico, F. L.

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Efficacy and Safety Outcomes of Extended Criteria Donor Kidneys by Subtype: Subgroup Analysis of BENEFIT‐EXT at 7 Years After Transplant by Florman, S., Becker, T., Bresnahan, B., Chevaile‐Ramos, A., Carvalho, D., Grannas, G., Muehlbacher, F., O'Connell, P. J., Meier‐Kriesche, H. U., Larsen, C. P.

“…The phase III Belatacept Evaluation of Nephroprotection and Efficacy as First‐Line Immunosuppression Trial–Extended Criteria Donors Trial (BENEFIT‐EXT) study…”
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Infiltrating Foxp3+ Regulatory T Cells From Spontaneously Tolerant Kidney Allografts Demonstrate Donor‐Specific Tolerance by Hu, M., Wang, C., Zhang, G. Y., Saito, M., Wang, Y. M., Fernandez, M. A., Wang, Y., Wu, H., Hawthorne, W. J., Jones, C., O'Connell, P. J., Sparwasser, T., Bishop, G. A., Sharland, A. F., Alexander, S. I.

“…Foxp3+ regulatory T cells (Tregs) have an essential role in immune and allograft tolerance. However, in both kidney and liver transplantation in humans, FOXP3+…”
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Uprating and rescuing small wastewater treatment facilities by adding tertiary treatment reed beds by Green, M.B, O'Connell, P.J, Griffin, P

“…A water utility developed use of gravel-filled constructed reed beds operating in a subsurface flow mode to polish secondary effluent to meet demanding…”
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Prolongation of Allograft Survival by Administration of Anti‐CD45RB Monoclonal Antibody Is Due to Alteration of CD45RBhi: CD45RBlo T‐Cell Proportions by Luke, P. P. W., Deng, J. P., Lian, D., O'Connell, P. J., Garcia, B., Jevnikar, A. M., Zhong, R.

“…CD45RB monoclonal antibody (mAb) therapy is capable of prolonging allograft survival. We have previously shown that CD45RB mAb enriches the CD45RBlo T‐cell…”
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Immobilization of Candida rugosa lipase on colloidal gas aphrons (CGAs) by O'Connell, P. J., Varley, J.

“…A novel technique for immobilization of Candida rugosa lipase onto anionic colloidal gas aphrons (CGAs) is described. CGAs are spherical microbubbles (10–100…”
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Electrochemical metallisation of carbon electrodes by O'Connell, P.J, O'Sullivan, C.K, Guilbault, G.G

“…A series of transition metals was electrodeposited on glassy carbon electrodes using cyclic voltammetry. The resultant chemically modified electrodes were…”
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Establishing a national program of islet transplantation in Australia by O'Connell, P J, Kay, T W H

“…We read with interest the opinion piece by Ricordi and Japour in STAT (August 27, 2019). It is interesting that the development of an appropriate funding…”
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Recovery of diabetic neuropathy after pancreas transplantation by Nankivell, B.J., AI-Harbi, I.S., Morris, J., Clouston, P.D., O'Connell, P.J., Chapman, J.R., Allen, R.D.M.

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Development of an interferent free amperometric biosensor for determination of l-lysine in food by Kelly, S.C., O’Connell, P.J., O’Sullivan, C.K., Guilbault, G.G.

“…A highly selective, fast responding amperometric biosensor is described, useful for the determination of l-lysine in food. Common electrochemical…”
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Differential regulation of T-cell proliferation and apoptosis by hepatic CD8α+ (lymphoid-related) and CD8α− (myeloid) dendritic cells by O’Connell, P.J, Logar, A.J, Thomson, A.W

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