Search Results - "O'CONNOR, W"

Update of the CHARMM All-Atom Additive Force Field for Lipids: Validation on Six Lipid Types by Klauda, Jeffery B, Venable, Richard M, Freites, J. Alfredo, O’Connor, Joseph W, Tobias, Douglas J, Mondragon-Ramirez, Carlos, Vorobyov, Igor, MacKerell, Alexander D, Pastor, Richard W

“…A significant modification to the additive all-atom CHARMM lipid force field (FF) is developed and applied to phospholipid bilayers with both choline and…”
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Cell adhesion and shape regulate TGF-beta1-induced epithelial-myofibroblast transition via MRTF-A signaling by O'Connor, Joseph W, Gomez, Esther W

“…Myofibroblasts, specialized cells that play important roles in wound healing and fibrosis, can develop from epithelial cells through an epithelial-mesenchymal…”
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Homologous-recombination-deficient tumours are dependent on Polθ-mediated repair by Ceccaldi, Raphael, Liu, Jessica C., Amunugama, Ravindra, Hajdu, Ildiko, Primack, Benjamin, Petalcorin, Mark I. R., O’Connor, Kevin W., Konstantinopoulos, Panagiotis A., Elledge, Stephen J., Boulton, Simon J., Yusufzai, Timur, D’Andrea, Alan D.

“…In studies in mammalian cells, polymerase theta (Polθ, also known as POLQ) is identified as the polymerase responsible for non-homologous end joining DNA…”
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Validity and reliability of the Moxy oxygen monitor during incremental cycling exercise by Crum, E. M., O'Connor, W. J., Van Loo, L., Valckx, M., Stannard, S. R.

“…Introduction: The Moxy is a novel, cutaneously placed muscle oxygen monitor which claims to measure local oxygen saturation (SmO 2 ) and total haemoglobin…”
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A Randomized, Placebo-Controlled Trial of Natalizumab for Relapsing Multiple Sclerosis by Polman, Chris H, O'Connor, Paul W, Havrdova, Eva, Hutchinson, Michael, Kappos, Ludwig, Miller, David H, Phillips, J. Theodore, Lublin, Fred D, Giovannoni, Gavin, Wajgt, Andrzej, Toal, Martin, Lynn, Frances, Panzara, Michael A, Sandrock, Alfred W

“…This placebo-controlled, randomized trial of patients with relapsing multiple sclerosis demonstrated benefits of natalizumab (an α 4 integrin antagonist) in…”
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Oral teriflunomide for patients with a first clinical episode suggestive of multiple sclerosis (TOPIC): a randomised, double-blind, placebo-controlled, phase 3 trial by Miller, Aaron E, Prof, Wolinsky, Jerry S, Prof, Kappos, Ludwig, MD, Comi, Giancarlo, Prof, Freedman, Mark S, Prof, Olsson, Tomas P, Prof, Bauer, Deborah, MS, Benamor, Myriam, MD, Truffinet, Philippe, MD, O'Connor, Paul W, Prof

“…Summary Background Teriflunomide is a once-daily oral immunomodulator approved for the treatment of relapsing-remitting multiple sclerosis. We aimed to assess…”
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Patient Enrollment Growth and Burnout in Primary Care at the Veterans Health Administration by O’Connor, Allyson W., Wong, Edwin S., Nelson, Karin M., Sears, Jeanne M., Helfrich, Christian D.

“…Background Patient enrollment levels at Veterans Health Administration (VHA) facilities change based on Veteran demand for care, potentially affecting demands…”
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A cluster-randomized crossover trial of Montessori activities delivered by family carers to nursing home residents with behavioral and psychological symptoms of dementia by Mbakile-Mahlanza, Lingani, van der Ploeg, Eva S, Busija, Lucy, Camp, Cameron, Walker, Helen, O'Connor, Daniel W

“…One-on-one structured Montessori-based activities conducted with people with dementia can improve agitation and enhance engagement. These activities may…”
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Office of Public Affairs update: a quarterly update from the American Society for Reproductive Medicine Office of Public Affairs on key developments in reproductive health policy by O’Connor, Rebecca W.

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Diagnostic criteria for multiple sclerosis: 2005 revisions to the "McDonald Criteria" by Polman, Chris H., Reingold, Stephen C., Edan, Gilles, Filippi, Massimo, Hartung, Hans-Peter, Kappos, Ludwig, Lublin, Fred D., Metz, Luanne M., McFarland, Henry F., O'Connor, Paul W., Sandberg-Wollheim, Magnhild, Thompson, Alan J., Weinshenker, Brian G., Wolinsky, Jerry S.

“…New diagnostic criteria for multiple sclerosis integrating magnetic resonance image assessment with clinical and other paraclinical methods were introduced in…”
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Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study by Havrdova, Eva, MD, Galetta, Steven, MD, Hutchinson, Michael, MD, Stefoski, Dusan, MD, Bates, David, MD, Polman, Chris H, MD, O'Connor, Paul W, MD, Giovannoni, Gavin, PhD, Phillips, J Theodore, MD, Lublin, Fred D, MD, Pace, Amy, ScD, Kim, Richard, MD, Hyde, Robert, PhD

“…Summary Background The efficacy of natalizumab on clinical and radiological measures in the phase III Natalizumab Safety and Efficacy in Relapsing-Remitting…”
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Somatic ERCC2 mutations correlate with cisplatin sensitivity in muscle-invasive urothelial carcinoma by Van Allen, Eliezer M, Mouw, Kent W, Kim, Philip, Iyer, Gopa, Wagle, Nikhil, Al-Ahmadie, Hikmat, Zhu, Cong, Ostrovnaya, Irina, Kryukov, Gregory V, O'Connor, Kevin W, Sfakianos, John, Garcia-Grossman, Ilana, Kim, Jaegil, Guancial, Elizabeth A, Bambury, Richard, Bahl, Samira, Gupta, Namrata, Farlow, Deborah, Qu, Angela, Signoretti, Sabina, Barletta, Justine A, Reuter, Victor, Boehm, Jesse, Lawrence, Michael, Getz, Gad, Kantoff, Philip, Bochner, Bernard H, Choueiri, Toni K, Bajorin, Dean F, Solit, David B, Gabriel, Stacey, D'Andrea, Alan, Garraway, Levi A, Rosenberg, Jonathan E

“…Cisplatin-based chemotherapy is the standard of care for patients with muscle-invasive urothelial carcinoma. Pathologic downstaging to pT0/pTis after…”
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Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer by O’Connor, Joseph W, Gomez, Esther W

“…Fibrosis, a disease that results in loss of organ function, contributes to a significant number of deaths worldwide and sustained fibrotic activation has been…”
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Bcl6 , Irf2 , and Notch2 promote nonclassical monocyte development by O'Connor, Kevin W, Liu, Tiantian, Kim, Sunkyung, Briseño, Carlos G, Georgopoulos, Katia, Murphy, Theresa L, Murphy, Kenneth M

“…Ly6C monocytes are a myeloid subset that specializes in the surveillance of vascular endothelium. Ly6C monocytes have been shown to derive from Ly6C monocytes…”
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Evidence Report: The efficacy and safety of mitoxantrone (Novantrone) in the treatment of multiple sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology by MARRIOTT, James J, MIYASAKI, Janis M, GRONSETH, Gary, O'CONNOR, Paul W

“…The chemotherapeutic agent mitoxantrone was approved for use in multiple sclerosis (MS) in 2000. After a review of all the available evidence, the original…”
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Disease activity return during natalizumab treatment interruption in patients with multiple sclerosis by O'CONNOR, P. W, GOODMAN, A, KAPPOS, L, LUBLIN, F. D, MILLER, D. H, POLMAN, C, RUDICK, R. A, ASCHENBACH, W, LUCAS, N

“…Due to a heightened risk of progressive multifocal leukoencephalopathy (PML) with increased natalizumab exposure, some physicians interrupt treatment of…”
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Office of Public Affairs update: A quarterly update from the American Society for Reproductive Medicine Office of Public Affairs on key developments in reproductive health policy by O’Connor, Rebecca W.

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Reintroducing a keystone bioturbator can facilitate microbial bioremediation in urban polluted sediments by Bugnot, A.B., Dafforn, K.A., Erickson, K., McGrath, A., O'Connor, W.A., Gribben, P.E.

“…Anthropogenic environmental stressors have significantly reduced biodiversity and the capacity of remnant natural habitats to deliver ecosystem functions and…”
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Lipid Membranes with a Majority of Cholesterol: Applications to the Ocular Lens and Aquaporin 0 by O’Connor, Joseph W, Klauda, Jeffery B

“…Using molecular dynamics (MD) simulations, we studied the structure and dynamics of two dimyristoylphosphatidylcholine (DMPC):cholesterol bilayers at…”
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Psychotropic medication deprescribing in residential aged care facilities: An exploratory study of the knowledge and attitudes of family members of residents with dementia by Lai, Rhoda, Withiel, Toni Dianne, Angelone, Melissa, Redpath, Cameron, O’Connor, Daniel W., Plakiotis, Christos

“…Objectives General practitioners face many barriers to deprescribing psychotropic medications in people with dementia in nursing homes, including a lack of…”
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