Search Results - "O'CONNOR, ANNE"
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1
Translation and religion: Issues of materiality
Published in Translation studies (02-09-2021)“…This article argues that the study of religious translation can greatly benefit from a material turn, that attention needs to be paid to the carriers and forms…”
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2
A whole-campus approach to technology and inclusion of students with disabilities in higher education in Ireland
Published in Disability & society (27-05-2024)“…The increasing demand for equitable higher education necessitates changes in how to consider and develop inclusive university settings. Using a…”
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3
Epsilon tubulin is an essential determinant of microtubule-based structures in male germ cells
Published in EMBO reports (12-06-2024)“…Alpha, beta, and gamma tubulins are essential building blocks for all eukaryotic cells. The functions of the non-canonical tubulins, delta, epsilon, and zeta,…”
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4
CRISP2 Is a Regulator of Multiple Aspects of Sperm Function and Male Fertility
Published in Endocrinology (Philadelphia) (01-04-2019)“…The cysteine-rich secretory proteins (CRISPs) are a group of proteins that show a pronounced expression biased to the male reproductive tract. Although sperm…”
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5
Diagnosis and treatment of familial hypercholesterolaemia
Published in European heart journal (01-04-2013)“…Familial hypercholesterolaemia (FH) is an autosomal dominant genetic disorder, associated with elevated levels of low-density lipoprotein-cholesterol (LDL-C),…”
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6
LRGUK-1 is required for basal body and manchette function during spermatogenesis and male fertility
Published in PLoS genetics (01-03-2015)“…Male infertility affects at least 5% of reproductive age males. The most common pathology is a complex presentation of decreased sperm output and abnormal…”
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Navigating the system: Physiotherapy student perceptions of performance-based assessment
Published in Medical teacher (02-09-2018)“…Background: Performance-based assessment (PBA) is an integral component of health professional education as it determines students' readiness for independent…”
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The katanin A-subunits KATNA1 and KATNAL1 act co-operatively in mammalian meiosis and spermiogenesis to achieve male fertility
Published in Development (Cambridge) (15-11-2023)“…Katanins, a class of microtubule-severing enzymes, are potent M-phase regulators in oocytes and somatic cells. How the complex and evolutionarily crucial, male…”
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Epididymal cysteine-rich secretory proteins are required for epididymal sperm maturation and optimal sperm function
Published in Molecular human reproduction (01-03-2018)“…Abstract STUDY QUESTION What is the role of epididymal cysteine-rich secretory proteins (CRISPs) in male fertility? SUMMARY ANSWER While epididymal CRISPs are…”
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Spastin is an essential regulator of male meiosis, acrosome formation, manchette structure and nuclear integrity
Published in Development (Cambridge) (15-03-2023)“…The development and function of male gametes is dependent on a dynamic microtubule network, yet how this is regulated remains poorly understood. We have…”
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In vivo evidence that RBM5 is a tumour suppressor in the lung
Published in Scientific reports (24-11-2017)“…Cigarette smoking is undoubtedly a risk factor for lung cancer. Moreover, smokers with genetic mutations on chromosome 3p21.3, a region frequently deleted in…”
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12
CRISP3 expression drives prostate cancer invasion and progression
Published in Endocrine-related cancer (01-07-2020)“…Identifying the factors stimulating prostate cancer cells migration and invasion has the potential to bring new therapeutic targets to the clinic…”
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13
The Sertoli cell expressed gene secernin‐1 (Scrn1) is dispensable for male fertility in the mouse
Published in Developmental dynamics (01-07-2021)“…Background Male infertility is a prevalent clinical presentation for which there is likely a strong genetic component due to the thousands of genes required…”
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CBE1 Is a Manchette- and Mitochondria-Associated Protein With a Potential Role in Somatic Cell Proliferation
Published in Endocrinology (Philadelphia) (01-11-2019)“…Ciliated bronchial epithelium 1 (CBE1) is a microtubule-associated protein localized to the manchette and developing flagellum during spermiogenesis and is…”
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15
Illusions of specificity in power-laden clinical performance assessment
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KATNB1 is a master regulator of multiple katanin enzymes in male meiosis and haploid germ cell development
Published in Development (Cambridge) (15-12-2021)“…Katanin microtubule-severing enzymes are crucial executers of microtubule regulation. Here, we have created an allelic loss-of-function series of the katanin…”
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An optimised STAPUT method for the purification of mouse spermatocyte and spermatid populations
Published in Molecular human reproduction (30-11-2019)“…The purification of individual male germ cell populations is integral for the molecular and biochemical characterisation of specific spermatogenic phases…”
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18
RABL2 Is Required for Hepatic Fatty Acid Homeostasis and Its Dysfunction Leads to Steatosis and a Diabetes-Like State
Published in Endocrinology (Philadelphia) (01-12-2016)“…Fatty liver, or hepatic steatosis, is an alarmingly common pathology in western societies, in large part because if left unheeded, it can lead to…”
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The PAPHIO study protocol: a randomised controlled trial with a 2 x 2 crossover design of physical activity adherence, psychological health and immunological outcomes in breast cancer survivors
Published in BMC public health (15-05-2020)“…The PAPHIO study; a randomized controlled trial with 2X2 crossover design will implement a self-directed physical activity program in which participants will…”
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PLAG1 deficiency impairs spermatogenesis and sperm motility in mice
Published in Scientific reports (13-07-2017)“…Deficiency in pleomorphic adenoma gene 1 (PLAG1) leads to reduced fertility in male mice, but the mechanism by which PLAG1 contributes to reproduction is…”
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