Search Results - "O'CARROLL, S. J"

Valproic acid induces caspase 3-mediated apoptosis in microglial cells by Dragunow, M., Greenwood, J.M., Cameron, R.E., Narayan, P.J., O’Carroll, S.J., Pearson, A.G., Gibbons, H.M.

“…Valproic acid is widely used for the treatment of epilepsy and mood disorders, but its mode of action is unclear. Treatment of neuronal cells with valproic…”
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The mitogen-activated/extracellular signal-regulated kinase kinase 1/2 inhibitor U0126 induces glial fibrillary acidic protein expression and reduces the proliferation and migration of C6 glioma cells by Lind, C.R.P., Gray, C.W., Pearson, A.G., Cameron, R.E., O’Carroll, S.J., Narayan, P.J., Lim, J., Dragunow, M.

“…The extracellular signal-regulated kinase (ERK) signaling pathway has been implicated in diverse cellular functions. ERK and its activating kinase,…”
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Efficient induction of cell death by adenoviruses requires binding of E1B55k and p53 by DIX, B. R, O'CARROLL, S. J, MYERS, C. J, EDWARDS, S. J, BRAITHWAITE, A. W

“…The use of an Elb55k-deficient adenovirus, ONYX-015, to selectively target tumor cells containing a mutated p53 gene has produced promising results. However,…”
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Quantifying adenoviral titers by spectrophotometry by O'Carroll, S J, Hall, A R, Myers, C J, Braithwaite, A W, Dix, B R

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p53-dependent cell death/apoptosis is required for a productive adenovirus infection by Braithwaite, Antony W, Hall, Anthony R, Dix, Brett R, O'Carroll, Simon J

“…The p53 tumor suppressor protein binds to both cellular and viral proteins, which influence its biological activity. One such protein is the large E1b tumor…”
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Extracellular signal-regulated kinase involvement in human astrocyte migration by Lim, Joanne H, Gibbons, Hannah M, O'Carroll, Simon J, Narayan, Pritika J, Faull, Richard L.M, Dragunow, Michael

“…Abstract Glial scar formation occurs after virtually any injury to the brain. The migration of astrocytes into regions of brain injury underlies the formation…”
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Nuclear prostaglandin receptors: role in pregnancy and parturition? by Helliwell, Rachel J.A, Berry, Elicia B.E, O’Carroll, Simon J, Mitchell, Murray D

“…The key regulatory role of prostanoids [prostaglandins (PGs) and thromboxanes (TXs)] in the maintenance of pregnancy and initiation of parturition has been…”
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Characterisation of Peptide5 systemic administration for treating traumatic spinal cord injured rats by Mao, Yilin, Nguyen, Tara, Tonkin, Ryan S., Lees, Justin G., Warren, Caitlyn, O’Carroll, Simon J., Nicholson, Louise F. B., Green, Colin R., Moalem-Taylor, Gila, Gorrie, Catherine A.

“…Systemic administration of a Connexin43 mimetic peptide, Peptide5, has been shown to reduce secondary tissue damage and improve functional recovery after…”
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