Search Results - "O'Brien, William T."

The NLRP3 inflammasome in traumatic brain injury: potential as a biomarker and therapeutic target by O'Brien, William T, Pham, Louise, Symons, Georgia F, Monif, Mastura, Shultz, Sandy R, McDonald, Stuart J

“…There is a great clinical need to identify the underlying mechanisms, as well as related biomarkers, and treatment targets, for traumatic brain injury (TBI)…”
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Pediatric Head and Neck Imaging: Understanding the Nuances and Complexities by O’Brien, William T.

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Common Neck and Otomastoid Infections in Children by O’Brien, William T.

“…Neck infections are common in children, though the clinical presentation is often vague and nonspecific. Therefore, imaging plays a key role in identifying the…”
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The Preoperative Sinus CT: Avoiding a "CLOSE" Call with Surgical Complications by O'Brien, Sr, William T, Hamelin, Stefan, Weitzel, Erik K

“…Although functional endoscopic sinus surgery is an effective means of treating patients with recurrent and refractory sinusitis, the procedure is not without…”
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The role of mTORC1 activation in seizure-induced exacerbation of Alzheimer's disease by Gourmaud, Sarah, Stewart, David A, Irwin, David J, Roberts, Nicholas, Barbour, Aaron J, Eberwine, Grace, O'Brien, William T, Vassar, Robert, Talos, Delia M, Jensen, Frances E

“…The risk of seizures is 10-fold higher in patients with Alzheimer's disease than the general population, yet the mechanisms underlying this susceptibility and…”
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The effect of resuscitative endovascular balloon occlusion of the aorta, partial aortic occlusion and aggressive blood transfusion on traumatic brain injury in a swine multiple injuries model by Johnson, M Austin, Williams, Timothy K, Ferencz, Sarah-Ashley E, Davidson, Anders J, Russo, Rachel M, O'Brien, Sr, William T, Galante, Joseph M, Grayson, J Kevin, Neff, Lucas P

“…Despite clinical reports of poor outcomes, the degree to which resuscitative endovascular balloon occlusion of the aorta (REBOA) exacerbates traumatic brain…”
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Nonsyndromic Congenital Causes of Sensorineural Hearing Loss in Children: An Illustrative Review by O'Brien, , Sr, William T, D'Arco, Felice, Onofrj, Valeria, Koch, Bernadette L

“…The purpose of this article is to provide an illustrative review of nonsyndromic congenital causes of sensorineural hearing loss (SNHL) in children. Early…”
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Diffusion Imaging Reveals Sex Differences in the White Matter Following Sports-Related Concussion by Wright, David K, Symons, Georgia F, O’Brien, William T, McDonald, Stuart J, Zamani, Akram, Major, Brendan, Chen, Zhibin, Costello, Daniel, Brady, Rhys D, Sun, Mujun, Law, Meng, O’Brien, Terence J, Mychasiuk, Richelle, Shultz, Sandy R

“…Abstract Sports-related concussion (SRC) is a serious health concern. However, the temporal profile of neuropathophysiological changes after SRC and how these…”
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Plasma biomarkers in chronic single moderate-severe traumatic brain injury by Spitz, Gershon, Hicks, Amelia J, McDonald, Stuart J, Dore, Vincent, Krishnadas, Natasha, O'Brien, Terence J, O'Brien, William T, Vivash, Lucy, Law, Meng, Ponsford, Jennie L, Rowe, Christopher, Shultz, Sandy R

“…Blood biomarkers are an emerging diagnostic and prognostic tool that reflect a range of neuropathological processes following traumatic brain injury (TBI)…”
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Incomplete partition type II in its various manifestations: isolated, in association with EVA, syndromic, and beyond; a multicentre international study by D’Arco, Felice, Kandemirli, Sedat G., Dahmoush, Hisham M., Alves, Cesar A. P. F., Severino, Mariasavina, Dellepiane, Francesco, Robson, Caroline D., Lequin, Maarten H., Rossi-Espagnet, Camilla, O’Brien, William T., Nash, Robert, Clement, Emma, Juliano, Amy F.

“…Purpose Incomplete partition type II (IP-II) is characterized by specific histological features and radiological appearance. It may occur in isolation or in…”
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The link between inner ear malformations and the rest of the body: what we know so far about genetic, imaging and histology by D’Arco, Felice, Sanverdi, Eser, O’Brien, William T., Taranath, Ajay, Talenti, Giacomo, Blaser, Susan I.

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Acute Flaccid Myelitis: A Multidisciplinary Protocol to Optimize Diagnosis and Evaluation by Vawter-Lee, Marissa, Peariso, Katrina, Frey, Mary, Bolikal, Priya, Schaffzin, Joshua K., Schwentker, Ann, O’Brien, William T., Zamor, Ronine, Kerrey, Benjamin T.

“…Acute flaccid myelitis is an emerging neurologic disease, first described in 2014 and predominantly affecting young children. Acute flaccid myelitis cases tend…”
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Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model by Pham, Louise, Wright, David K., O'Brien, William T., Bain, Jesse, Huang, Cheng, Sun, Mujun, Casillas-Espinosa, Pablo M., Shah, Anup D., Schittenhelm, Ralf B., Sobey, Christopher G., Brady, Rhys D., O'Brien, Terence J., Mychasiuk, Richelle, Shultz, Sandy R., McDonald, Stuart J.

“…A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological conditions, however there is still much unknown about the…”
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Monitoring the acute and subacute recovery of cognitive ocular motor changes after a sports-related concussion by Symons, Georgia F, O’Brien, William T, Abel, Larry, Chen, Zhibin, Costello, Daniel M, O’Brien, Terence J, Kolbe, Scott, Fielding, Joanne, Shultz, Sandy R, Clough, Meaghan

“…Abstract Identifying when recovery from a sports-related concussion (SRC) has occurred remains a challenge in clinical practice. This study investigated the…”
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White and Gray Matter Abnormalities in Australian Footballers With a History of Sports-Related Concussion: An MRI Study by Major, Brendan, Symons, Georgia F, Sinclair, Ben, O’Brien, William T, Costello, Daniel, Wright, David K, Clough, Meaghan, Mutimer, Steven, Sun, Mujun, Yamakawa, Glenn R, Brady, Rhys D, O’Sullivan, Michael J, Mychasiuk, Richelle, McDonald, Stuart J, O’Brien, Terence J, Law, Meng, Kolbe, Scott, Shultz, Sandy R

“…Abstract Sports-related concussion (SRC) is a form of mild traumatic brain injury that has been linked to long-term neurological abnormalities. Australian…”
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Decrease in Plasma miR-27a and miR-221 After Concussion in Australian Football Players by Shultz, Sandy R, Taylor, Caroline J, Aggio-Bruce, Riemke, O’Brien, William T, Sun, Mujun, Cioanca, Adrian V, Neocleous, George, Symons, Georgia F, Brady, Rhys D, Hardikar, Anandwardhan A, Joglekar, Mugdha V, Costello, Daniel M, O’Brien, Terence J, Natoli, Riccardo, McDonald, Stuart J

“…Introduction: Sports-related concussion (SRC) is a common form of brain injury that lacks reliable methods to guide clinical decisions. MicroRNAs (miRNAs) can…”
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Pathophysiology, blood biomarkers, and functional deficits after intimate partner violence-related brain injury: Insights from emergency department patients and a new rat model by Sun, Mujun, Symons, Georgia F., Spitz, Gershon, O’Brien, William T., Baker, Tamara L, Fan, Jianjia, Martins, Beatriz D., Allen, Josh, Giesler, Lauren P., Mychasiuk, Richelle, van Donkelaar, Paul, Brand, Justin, Christie, Brian, O’Brien, Terence J., O’Sullivan, Michael J., Mitra, Biswadev, Wellington, Cheryl, McDonald, Stuart J., Shultz, Sandy R.

“…•Brain injury in intimate partner violence (IPV) involves concussion and/or strangulation.•Acute IPV patients with concussion had worse brain injury biomarkers…”
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Prolonged elevation of serum neurofilament light after concussion in male Australian football players by McDonald, Stuart J, O'Brien, William T, Symons, Georgia F, Chen, Zhibin, Bain, Jesse, Major, Brendan P, Costello, Daniel, Yamakawa, Glenn, Sun, Mujun, Brady, Rhys D, Mitra, Biswadev, Mychasiuk, Richelle, O'Brien, Terence J, Shultz, Sandy R

“…Biomarkers that can objectively guide the diagnosis of sports-related concussion, and consequent return-to-play decisions, are urgently needed. In this study,…”
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Serum Neurofilament Light as a Biomarker of Traumatic Brain Injury in the Presence of Concomitant Peripheral Injury by Wong, Ker Rui, O’Brien, William T, Sun, Mujun, Yamakawa, Glenn, O’Brien, Terence J, Mychasiuk, Richelle, Shultz, Sandy R, McDonald, Stuart J, Brady, Rhys D

“…Introduction: Serum neurofilament light (NfL) is an emerging biomarker of traumatic brain injury (TBI). However, the effect of peripheral injuries such as long…”
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Acute effects of single and repeated mild traumatic brain injury on levels of neurometabolites, lipids, and mitochondrial function in male rats by Allen, Josh, Pham, Louise, Bond, Simon T, O'Brien, William T, Spitz, Gershon, Shultz, Sandy R, Drew, Brian G, Wright, David K, McDonald, Stuart J

“…Mild traumatic brain injuries (mTBIs) are the most common form of acquired brain injury. Symptoms of mTBI are thought to be associated with a neuropathological…”
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