Search Results - "O'Brien, Peter"
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100 Most Cited Articles in Orthopaedic Surgery
Published in Clinical orthopaedics and related research (01-05-2011)“…Background Citation analysis reflects the recognition a work has received in the scientific community by its peers, and is a common method to determine…”
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High‐Content Analysis in Toxicology: Screening Substances for Human Toxicity Potential, Elucidating Subcellular Mechanisms and In Vivo Use as Translational Safety Biomarkers
Published in Basic & clinical pharmacology & toxicology (01-07-2014)“…High‐content analysis (HCA) of in vitro biochemical and morphological effects of classic (small molecule) drugs and chemicals is concordant with potential for…”
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High content analysis provides mechanistic insights on the pathways of toxicity induced by amine-modified polystyrene nanoparticles
Published in PloS one (19-09-2014)“…The fast-paced development of nanotechnology needs the support of effective safety testing. We have developed a screening platform measuring simultaneously…”
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A head-to-head Caco-2 assay comparison of the mechanisms of action of the intestinal permeation enhancers: SNAC and sodium caprate (C10)
Published in European journal of pharmaceutics and biopharmaceutics (01-07-2020)“…Cartoon comparing effects of SNAC and C10 on parameters in Caco-2 epithelia. [Display omitted] Salcaprozate sodium (SNAC) and sodium caprate (C10) are the two…”
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III-V-on-Silicon Integration: From Hybrid Devices to Heterogeneous Photonic Integrated Circuits
Published in IEEE journal of selected topics in quantum electronics (01-03-2020)“…Heterogeneous integration of III-V materials onto silicon photonics has experienced enormous progress in the last few years, setting the groundwork for the…”
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Thermal remediation alters soil properties – a review
Published in Journal of environmental management (15-01-2018)“…Contaminated soils pose a risk to human and ecological health, and thermal remediation is an efficient and reliable way to reduce soil contaminant…”
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Methotrexate induced mitochondrial injury and cytochrome c release in rat liver hepatocytes
Published in Drug and chemical toxicology (New York, N.Y. 1978) (02-01-2018)“…Methotrexate (MTX) is a folic acid antagonist that is widely used to treat a variety of diseases. One of the most serious side effects of MTX therapy is…”
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Photonic Integrated Circuit-Based FMCW Coherent LiDAR
Published in Journal of lightwave technology (01-10-2018)“…We present the demonstration of an integrated frequency modulated continuous wave LiDAR on a silicon platform. The waveform calibration, the scanning system,…”
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Synthesis of Spirocyclic Indolenines
Published in Chemistry : a European journal (24-02-2016)“…This Review provides an in‐depth account of the synthesis of spirocyclic indolenines. Over the last 77 years, a wide array of diverse synthetic methods has…”
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Optical and Electronic Packaging Processes for Silicon Photonic Systems
Published in Journal of lightwave technology (01-03-2015)“…Fiber optic interconnection processes and hybrid integration of electronic devices for high speed Si photonic systems are presented. Thermal effects arising…”
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Bioluminescent flashes drive nighttime schooling behavior and synchronized swimming dynamics in flashlight fish
Published in PloS one (14-08-2019)“…Schooling fishes, like flocking birds and swarming insects, display remarkable behavioral coordination. While over 25% of fish species exhibit schooling…”
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Diabetic polyneuropathies: update on research definition, diagnostic criteria and estimation of severity
Published in Diabetes/metabolism research and reviews (01-10-2011)“…Prior to a joint meeting of the Neurodiab Association and International Symposium on Diabetic Neuropathy held in Toronto, Ontario, Canada, 13‐18 October 2009,…”
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Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties
Published in Free radical biology & medicine (01-08-2004)“…Flavonoids, including isoflavones, are natural components in our diet and, with the burgeoning interest in alternative medicine, are increasingly being…”
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Evaluation of Techniques for Measuring Microbial Hazards in Bathing Waters: A Comparative Study
Published in PloS one (23-05-2016)“…Recreational water quality is commonly monitored by means of culture based faecal indicator organism (FIOs) assays. However, these methods are costly and…”
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Drawing Upon Finnegans Wake
Published in Art/Research International (15-09-2018)“…LOTS OF FUN WITH FINNEGANS WAKE is my six-year project to annotate / illustrate / disrupt the 628 pages of James Joyce’s final book. I’ve been reading…”
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Silver(I)- or Copper(II)-Mediated Dearomatization of Aromatic Ynones: Direct Access to Spirocyclic Scaffolds
Published in Angewandte Chemie International Edition (22-06-2015)“…A high‐yielding silver(I)‐ or copper(II)‐catalyzed dearomatizing spirocyclization strategy allows the conversion of simple aromatic compounds that contain…”
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Aldehyde Sources, Metabolism, Molecular Toxicity Mechanisms, and Possible Effects on Human Health
Published in Critical reviews in toxicology (01-08-2005)“…Aldehydes are organic compounds that are widespread in nature. They can be formed endogenously by lipid peroxidation (LPO), carbohydrate or metabolism…”
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Silica-Supported Silver Nitrate as a Highly Active Dearomatizing Spirocyclization Catalyst: Synergistic Alkyne Activation by Silver Nanoparticles and Silica
Published in Angewandte Chemie International Edition (24-10-2016)“…Silica‐supported AgNO3 (AgNO3–SiO2) catalyzes the dearomatizing spirocyclization of alkyne‐tethered aromatics far more effectively than the analogous…”
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Catalyst-Driven Scaffold Diversity: Selective Synthesis of Spirocycles, Carbazoles and Quinolines from Indolyl Ynones
Published in Chemistry : a European journal (20-06-2016)“…Medicinally relevant spirocyclic indolenines, carbazoles and quinolines can each be directly synthesised selectively from common indolyl ynone starting…”
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Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function
Published in Diabetes (New York, N.Y.) (01-01-2010)“…Age, Obesity, and Sex Effects on Insulin Sensitivity and Skeletal Muscle Mitochondrial Function Helen Karakelides , Brian A. Irving , Kevin R. Short , Peter…”
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