Search Results - "O'Brien, Lynne T."

Multiple newly identified loci associated with prostate cancer susceptibility by English, Dallas R, Bagnato, Melisa, Christmas, Tim, Severi, Gianluca, Gehr-Swain, Beatrice N, Olama, Ali Amin Al, Ogden, Chris, Parker, Christopher C, Field, Helen I, Easton, Douglas F, Jugurnauth, Sarah K, Brown, Paul M, Dearnaley, David P, Southey, Melissa C, Thompson, Alan, Huddart, Robert A, Horwich, Alan, Neal, David E, Muir, Kenneth R, Hall, Amanda L, Jhavar, Sameer G, Hamdy, Freddie C, Donovan, Jenny L, Tymrakiewicz, Malgorzata, Khoo, Vincent S, Hopper, John L, Bryant, Sarah L, Ardern-Jones, Audrey T, Fisher, Cyril, Kote-Jarai, Zsofia, Giles, Graham G, Jamieson, Charles, Smith, Charmaine, O'Brien, Lynne T, Eeles, Rosalind A, Edwards, Stephen M, Wilkinson, Rosemary A, Cox, Angie, Lewis, Sarah, Cooper, Colin S, Morrison, Jonathan, Guy, Michelle, Lophatananon, Artitaya, Mulholland, Shani, Leongamornlert, Daniel A, Woodhouse, Christopher J

“…Prostate cancer is the most common cancer affecting males in developed countries. It shows consistent evidence of familial aggregation, but the causes of this…”
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Multiple loci on 8q24 associated with prostate cancer susceptibility by Easton, Douglas F, Al Olama, Ali Amin, Kote-Jarai, Zsofia, Giles, Graham G, Guy, Michelle, Morrison, Jonathan, Severi, Gianluca, Leongamornlert, Daniel A, Tymrakiewicz, Malgorzata, Jhavar, Sameer, Saunders, Ed, Hopper, John L, Southey, Melissa C, Muir, Kenneth R, English, Dallas R, Dearnaley, David P, Ardern-Jones, Audrey T, Hall, Amanda L, O'Brien, Lynne T, Wilkinson, Rosemary A, Sawyer, Emma, Lophatananon, Artitaya, Horwich, Alan, Huddart, Robert A, Khoo, Vincent S, Parker, Christopher C, Woodhouse, Christopher J, Thompson, Alan, Christmas, Tim, Ogden, Chris, Cooper, Colin, Donovan, Jenny L, Hamdy, Freddie C, Neal, David E, Eeles, Rosalind A

“…Previous studies have identified multiple loci on 8q24 associated with prostate cancer risk. We performed a comprehensive analysis of SNP associations across…”
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A risk prediction algorithm based on family history and common genetic variants: application to prostate cancer with potential clinical impact by MacInnis, Robert J., Antoniou, Antonis C., Eeles, Rosalind A., Severi, Gianluca, Al Olama, Ali Amin, McGuffog, Lesley, Kote-Jarai, Zsofia, Guy, Michelle, O'Brien, Lynne T., Hall, Amanda L., Wilkinson, Rosemary A., Sawyer, Emma, Ardern-Jones, Audrey T., Dearnaley, David P., Horwich, Alan, Khoo, Vincent S., Parker, Christopher C., Huddart, Robert A., Van As, Nicholas, McCredie, Margaret R., English, Dallas R., Giles, Graham G., Hopper, John L., Easton, Douglas F.

“…Genome wide association studies have identified several single nucleotide polymorphisms (SNPs) that are independently associated with small increments in risk…”
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Clinical implications of family history of prostate cancer and genetic risk single nucleotide polymorphism (SNP) profiles in an active surveillance cohort by Goh, Chee L., Saunders, Edward J., Leongamornlert, Daniel A., Tymrakiewicz, Malgorzata, Thomas, Karen, Selvadurai, Elizabeth D., Woode‐Amissah, Ruth, Dadaev, Tokhir, Mahmud, Nadiya, Castro, Elena, Olmos, David, Guy, Michelle, Govindasami, Koveela, O'Brien, Lynne T., Hall, Amanda L., Wilkinson, Rosemary A., Sawyer, Emma J., Al Olama, Ali Amin, Easton, Douglas F., Kote‐Jarai, Zsofia, Parker, Chris C., Eeles, Rosalind A.

“…What's known on the subject? and What does the study add? Family history (FH) is a major risk factor for the development of prostate cancer. The search for…”
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Prostate cancer segregation analyses using 4390 families from UK and Australian population-based studies by MacInnis, Robert J., Antoniou, Antonis C., Eeles, Rosalind A., Severi, Gianluca, Guy, Michelle, McGuffog, Lesley, Hall, Amanda L., O'Brien, Lynne T., Wilkinson, Rosemary A., Dearnaley, David P., Ardern-Jones, Audrey T., Horwich, Alan, Khoo, Vincent S., Parker, Christopher C., Huddart, Robert A., McCredie, Margaret R., Smith, Charmaine, Southey, Melissa C., Staples, Margaret P., English, Dallas R., Hopper, John L., Giles, Graham G., Easton, Douglas F.

“…Familial aggregation of prostate cancer is likely to be due to multiple susceptibility loci, perhaps acting in conjunction with shared lifestyle risk factors…”
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Identification of new genetic risk factors for prostate cancer by Guy, Michelle, Kote-Jarai, Zsofia, Giles, Graham G, Al Olama, Ali Amin, Jugurnauth, Sarah K, Mulholland, Shani, Leongamornlert, Daniel A, Edwards, Stephen M, Morrison, Jonathan, Field, Helen I, Southey, Melissa C, Severi, Gianluca, Donovan, Jenny L, Hamdy, Freddie C, Dearnaley, David P, Muir, Kenneth R, Smith, Charmaine, Bagnato, Melisa, Ardern-Jones, Audrey T, Hall, Amanda L, O'Brien, Lynne T, Gehr-Swain, Beatrice N, Wilkinson, Rosemary A, Cox, Angela, Lewis, Sarah, Brown, Paul M, Jhavar, Sameer G, Tymrakiewicz, Malgorzata, Lophatananon, Artitaya, Bryant, Sarah L, Horwich, Alan, Huddart, Robert A, Khoo, Vincent S, Parker, Christopher C, Woodhouse, Christopher J, Thompson, Alan, Christmas, Tim, Ogden, Chris, Fisher, Cyril, Jameson, Charles, Cooper, Colin S, English, Dallas R, Hopper, John L, Neal, David E, Easton, Douglas F, Eeles, Rosalind A

“…There is evidence that a substantial part of genetic predisposition to prostate cancer (PCa) may be due to lower penetrance genes which are found by…”
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Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert by Ghoussaini, Maya, Song, Honglin, Koessler, Thibaud, Al Olama, Ali Amin, Kote-Jarai, Zsofia, Driver, Kristy E., Pooley, Karen A., Ramus, Susan J., Kjaer, Susanne Krüger, Hogdall, Estrid, DiCioccio, Richard A., Whittemore, Alice S., Gayther, Simon A., Giles, Graham G., Guy, Michelle, Edwards, Stephen M., Morrison, Jonathan, Donovan, Jenny L., Hamdy, Freddie C., Dearnaley, David P., Ardern-Jones, Audrey T., Hall, Amanda L., O'Brien, Lynne T., Gehr-Swain, Beatrice N., Wilkinson, Rosemary A., Brown, Paul M., Hopper, John L., Neal, David E., Pharoah, Paul D. P., Ponder, Bruce A. J., Eeles, Rosalind A., Easton, Douglas F., Dunning, Alison M.

“…Recent studies based on genome-wide association, linkage, and admixture scan analysis have reported associations of various genetic variants in 8q24 with…”
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