Search Results - "O'Brien, Caitlin E"

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    Association of diastolic blood pressure with coronary perfusion pressure during resuscitation in pediatric swine by Sorcher, Jill L, Santos, Polan T, Adams, Shawn, Kulikowicz, Ewa, Vaidya, Dhananjay, Lee, Jennifer K, Hunt, Elizabeth A, Koehler, Raymond C, Shaffner, Donald H, O'Brien, Caitlin E

    Published in Pediatric research (15-07-2024)
    “…Diastolic blood pressure (DBP) is suggested as a surrogate for coronary perfusion pressure (CPP) during cardiopulmonary resuscitation. We examined the…”
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    Hypoxia-Ischemia and Hypothermia Independently and Interactively Affect Neuronal Pathology in Neonatal Piglets with Short-Term Recovery by O'Brien, Caitlin E, Santos, Polan T, Kulikowicz, Ewa, Reyes, Michael, Koehler, Raymond C, Martin, Lee J, Lee, Jennifer K

    Published in Developmental neuroscience (01-01-2019)
    “…Therapeutic hypothermia is the standard of clinical care for moderate neonatal hypoxic-ischemic encephalopathy. We investigated the independent and interactive…”
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    Phospholipid Homeostasis Regulates Dendrite Morphogenesis in Drosophila Sensory Neurons by Meltzer, Shan, Bagley, Joshua A., Perez, Gerardo Lopez, O’Brien, Caitlin E., DeVault, Laura, Guo, Yanmeng, Jan, Lily Yeh, Jan, Yuh-Nung

    Published in Cell reports (Cambridge) (24-10-2017)
    “…Disruptions in lipid homeostasis have been observed in many neurodevelopmental disorders that are associated with dendrite morphogenesis defects. However, the…”
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    Neurologic effects of short-term treatment with a soluble epoxide hydrolase inhibitor after cardiac arrest in pediatric swine by O'Brien, Caitlin E, Santos, Polan T, Kulikowicz, Ewa, Lee, Jennifer K, Koehler, Raymond C, Martin, Lee J

    Published in BMC neuroscience (31-10-2020)
    “…Cardiac arrest (CA) is the most common cause of acute neurologic insult in children. Many survivors have significant neurocognitive deficits at 1 year of…”
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    Proteasome Biology Is Compromised in White Matter After Asphyxic Cardiac Arrest in Neonatal Piglets by Santos, Polan T, O'Brien, Caitlin E, Chen, May W, Hopkins, C Danielle, Adams, Shawn, Kulikowicz, Ewa, Singh, Rashmi, Koehler, Raymond C, Martin, Lee J, Lee, Jennifer K

    Published in Journal of the American Heart Association (16-10-2018)
    “…Background Neurological deficits in hypoxic-ischemic encephalopathy, even with therapeutic hypothermia, are partially attributed to white matter injury. We…”
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    Maternal and Embryonic Stress Influence Offspring Behavior in the Cuttlefish Sepia officinalis by O'Brien, Caitlin E, Jozet-Alves, Christelle, Mezrai, Nawel, Bellanger, Cécile, Darmaillacq, Anne-Sophie, Dickel, Ludovic

    Published in Frontiers in physiology (01-12-2017)
    “…Stress experienced during prenatal development-either applied to reproducing females (maternal stress), directly to developing offspring (embryonic stress) or…”
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    The use of pressure‐controlled mechanical ventilation in a swine model of intraoperative pediatric cardiac arrest by Lapid, Francis M., O'Brien, Caitlin E., Kudchadkar, Sapna R., Lee, Jennifer K., Hunt, Elizabeth A., Koehler, Raymond C., Shaffner, Donald H., Ramamoorthy, Chandra

    Published in Pediatric anesthesia (01-04-2020)
    “…Background Current pediatric resuscitation guidelines suggest that resuscitators using an advanced airway deliver 8‐10 breaths per minute while carefully…”
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    Visual Ecology and the Development of Visually Guided Behavior in the Cuttlefish by Darmaillacq, Anne-Sophie, Mezrai, Nawel, O'Brien, Caitlin E, Dickel, Ludovic

    Published in Frontiers in physiology (13-06-2017)
    “…Cuttlefish are highly visual animals, a fact reflected in the large size of their eyes and visual-processing centers of their brain. Adults detect their prey…”
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    Use of an end-tidal carbon dioxide-guided algorithm during cardiopulmonary resuscitation improves short-term survival in paediatric swine by O'Brien, Caitlin E., Santos, Polan T., Kulikowicz, Ewa, Adams, Shawn, Lee, Jennifer K., Hunt, Elizabeth A., Koehler, Raymond C., Shaffner, Donald H.

    Published in Resuscitation plus (01-12-2021)
    “…To evaluate an algorithm that uses an end-tidal carbon dioxide (ETCO2) target of ≥ 30 torr to guide specific changes in chest compression rate and epinephrine…”
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    Interorganelle communication, aging, and neurodegeneration by Petkovic, Maja, O'Brien, Caitlin E, Jan, Yuh Nung

    Published in Genes & development (01-04-2021)
    “…Our cells are comprised of billions of proteins, lipids, and other small molecules packed into their respective subcellular organelles, with the daunting task…”
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    Microglial Beclin 1 Regulates Retromer Trafficking and Phagocytosis and Is Impaired in Alzheimer’s Disease by Lucin, Kurt M., O’Brien, Caitlin E., Bieri, Gregor, Czirr, Eva, Mosher, Kira I., Abbey, Rachelle J., Mastroeni, Diego F., Rogers, Joseph, Spencer, Brian, Masliah, Eliezer, Wyss-Coray, Tony

    Published in Neuron (Cambridge, Mass.) (04-09-2013)
    “…Phagocytosis controls CNS homeostasis by facilitating the removal of unwanted cellular debris. Accordingly, impairments in different receptors or proteins…”
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    The GARP complex prevents sterol accumulation at the trans-Golgi network during dendrite remodeling by O'Brien, Caitlin E, Younger, Susan H, Jan, Lily Yeh, Jan, Yuh Nung

    Published in The Journal of cell biology (02-01-2023)
    “…Membrane trafficking is essential for sculpting neuronal morphology. The GARP and EARP complexes are conserved tethers that regulate vesicle trafficking in the…”
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    A preliminary investigation of the response of Octopus vulgaris to experimental stimuli in the wild by O'Brien, Caitlin E, Di Miccoli, Valentina, Fiorito, Graziano

    Published in Journal of molluscan studies (17-09-2021)
    “…ABSTRACT We tested the feasibility of conducting three standard behavioural tests modified from laboratory experiments with Octopus vulgaris in its natural…”
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    Combining Hypothermia and Oleuropein Subacutely Protects Subcortical White Matter in a Swine Model of Neonatal Hypoxic-Ischemic Encephalopathy by Lee, Jennifer K, Santos, Polan T, Chen, May W, O’Brien, Caitlin E, Kulikowicz, Ewa, Adams, Shawn, Hardart, Henry, Koehler, Raymond C, Martin, Lee J

    “…Abstract Neonatal hypoxia-ischemia (HI) causes white matter injury that is not fully prevented by therapeutic hypothermia. Adjuvant treatments are needed. We…”
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    The Current State of Cephalopod Science and Perspectives on the Most Critical Challenges Ahead From Three Early-Career Researchers by O'Brien, Caitlin E, Roumbedakis, Katina, Winkelmann, Inger E

    Published in Frontiers in physiology (06-06-2018)
    “…Here, three researchers who have recently embarked on careers in cephalopod biology discuss the current state of the field and offer their hopes for the…”
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    Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration by Bieri, Gregor, Lucin, Kurt M, O'Brien, Caitlin E, Zhang, Hui, Villeda, Saul A, Wyss-Coray, Tony

    Published in Molecular neurodegeneration (29-12-2018)
    “…Neuronal cell loss contributes to the pathology of acute and chronic neurodegenerative diseases, including Alzheimer's disease (AD). It remains crucial to…”
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    Beclin 1 regulates neuronal transforming growth factor-β signaling by mediating recycling of the type I receptor ALK5 by O'Brien, Caitlin E, Bonanno, Liana, Zhang, Hui, Wyss-Coray, Tony

    Published in Molecular neurodegeneration (21-12-2015)
    “…Beclin 1 is a key regulator of multiple trafficking pathways, including autophagy and receptor recycling in yeast and microglia. Decreased beclin 1 levels in…”
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