Search Results - "O'BRIEN, Terence J"

Imaging Microglial Activation with TSPO PET: Lighting Up Neurologic Diseases? by Vivash, Lucy, O'Brien, Terence J

“…Neuroinflammation is implicated in the pathogenesis of a wide range of neurologic and neuropsychiatric diseases. For over 20 years, (11)C-PK11195 PET, which…”
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Risk Factors and Prognosis of Early Posttraumatic Seizures in Moderate to Severe Traumatic Brain Injury by Laing, Joshua, Gabbe, Belinda, Chen, Zhibin, Perucca, Piero, Kwan, Patrick, O'Brien, Terence J

“…Early posttraumatic seizures (EPS) that may occur following a traumatic brain injury (TBI) are associated with poorer outcomes and development of posttraumatic…”
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Inflammation in epileptogenesis after traumatic brain injury by Webster, Kyria M, Sun, Mujun, Crack, Peter, O'Brien, Terence J, Shultz, Sandy R, Semple, Bridgette D

“…Epilepsy is a common and debilitating consequence of traumatic brain injury (TBI). Seizures contribute to progressive neurodegeneration and poor functional and…”
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Inflammation, ictogenesis, and epileptogenesis: An exploration through human disease by Tan, Tracie Huey‐Lin, Perucca, Piero, O’Brien, Terence J., Kwan, Patrick, Monif, Mastura

“…Epilepsy is seen historically as a disease of aberrant neuronal signaling manifesting as seizures. With the discovery of numerous auto‐antibodies and the…”
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Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy by Kamitaki, Brad K., Janmohamed, Mubeen, Kandula, Padmaja, Elder, Christopher, Mani, Ram, Wong, Stephen, Perucca, Piero, O’Brien, Terence J., Lin, Haiqun, Heiman, Gary A., Choi, Hyunmi

“…Objective We sought to determine which combination of clinical and electroencephalography (EEG) characteristics differentiate between an antiseizure medication…”
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Contemporary advances in anti-NMDAR antibody (Ab)-mediated encephalitis by Seery, Nabil, Butzkueven, Helmut, O’Brien, Terence J., Monif, Mastura

“…The study of antibody (Ab)-mediated encephalitis has advanced dramatically since the discovery of antibodies directed against the N-methyl-D-aspartate receptor…”
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Rare antibody-mediated and seronegative autoimmune encephalitis: An update by Seery, Nabil, Butzkueven, Helmut, O’Brien, Terence J., Monif, Mastura

“…Paralleling advances with respect to more common antibody-mediated encephalitides, such as anti-N-methyl-D-aspartate receptor (NMDAR) and anti-leucine-rich…”
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The pathophysiology of cardiac dysfunction in epilepsy by Ravindran, Krishnan, Powell, Kim L, Todaro, Marian, O’Brien, Terence J

“…Highlights • Dysfunction in cardiac electrophysiology is an established consequence of chronic epilepsy. • Cardiac ion channel expression is believed to be…”
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Sleep-disordered breathing in epilepsy: epidemiology, mechanisms, and treatment by Sivathamboo, Shobi, Perucca, Piero, Velakoulis, Dennis, Jones, Nigel C, Goldin, Jeremy, Kwan, Patrick, O'Brien, Terence J

“…Epilepsy is a group of neurological conditions in which there is a pathological and enduring predisposition to generate recurrent seizures. Evidence over the…”
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Perampanel and pregnancy by Vazquez, Blanca, Tomson, Torbjörn, Dobrinsky, Cindy, Schuck, Edgar, O’Brien, Terence J.

“…Objective The objective was to summarize pregnancy and fetal/postnatal outcomes following maternal perampanel exposure using preclinical and clinical data, and…”
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Contemporary advances in antibody-mediated encephalitis: anti-LGI1 and anti-Caspr2 antibody (Ab)-mediated encephalitides by Seery, Nabil, Butzkueven, Helmut, O’Brien, Terence J., Monif, Mastura

“…Encephalitides with antibodies directed against leucine-rich glioma-inactivated 1 (LGI1) and contactin-associated protein-like 2 (Caspr2) represent two…”
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Biomarkers add value to traumatic brain injury prognosis by McDonald, Stuart J, O’Brien, Terence J, Shultz, Sandy R

“…[...]the interassay variability of the tests used by the CENTER-TBI researchers were higher than those reported in other studies. [...]the assay systems used…”
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Interleukin-1 Receptor in Seizure Susceptibility after Traumatic Injury to the Pediatric Brain by Semple, Bridgette D, O'Brien, Terence J, Gimlin, Kayleen, Wright, David K, Kim, Shi Eun, Casillas-Espinosa, Pablo M, Webster, Kyria M, Petrou, Steven, Noble-Haeusslein, Linda J

“…Epilepsy after pediatric traumatic brain injury (TBI) is associated with poor quality of life. This study aimed to characterize post-traumatic epilepsy in a…”
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Antagonism of the ATP-gated P2X7 receptor: a potential therapeutic strategy for cancer by Drill, Matthew, Jones, Nigel C., Hunn, Martin, O’Brien, Terence J., Monif, Mastura

“…The P2X receptor 7 (P2X7R) is a plasma membrane receptor sensing extracellular ATP associated with a wide variety of cellular functions. It is most commonly…”
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Perampanel for tonic-clonic seizures in idiopathic generalized epilepsy: A randomized trial by French, Jacqueline A, Krauss, Gregory L, Wechsler, Robert T, Wang, Xue-Feng, DiVentura, Bree, Brandt, Christian, Trinka, Eugen, OʼBrien, Terence J, Laurenza, Antonio, Patten, Anna, Bibbiani, Francesco

“…OBJECTIVE:To assess efficacy and safety of adjunctive perampanel in patients with drug-resistant, primary generalized tonic-clonic (PGTC) seizures in…”
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Psychotic disorders induced by antiepileptic drugs in people with epilepsy by Chen, Ziyi, Lusicic, Ana, O'Brien, Terence J, Velakoulis, Dennis, Adams, Sophia J, Kwan, Patrick

“…Antiepileptic drug treatment can induce psychosis in some patients. However, there are no agreed definitions or diagnostic criteria for antiepileptic…”
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Assessment of Safety of a Fully Implanted Endovascular Brain-Computer Interface for Severe Paralysis in 4 Patients: The Stentrode With Thought-Controlled Digital Switch (SWITCH) Study by Mitchell, Peter, Lee, Sarah C M, Yoo, Peter E, Morokoff, Andrew, Sharma, Rahul P, Williams, Daryl L, MacIsaac, Christopher, Howard, Mark E, Irving, Lou, Vrljic, Ivan, Williams, Cameron, Bush, Steven, Balabanski, Anna H, Drummond, Katharine J, Desmond, Patricia, Weber, Douglas, Denison, Timothy, Mathers, Susan, O'Brien, Terence J, Mocco, J, Grayden, David B, Liebeskind, David S, Opie, Nicholas L, Oxley, Thomas J, Campbell, Bruce C V

“…Brain-computer interface (BCI) implants have previously required craniotomy to deliver penetrating or surface electrodes to the brain. Whether a minimally…”
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Seven‐tesla quantitative magnetic resonance spectroscopy of glutamate, γ‐aminobutyric acid, and glutathione in the posterior cingulate cortex/precuneus in patients with epilepsy by Gonen, Ofer M., Moffat, Bradford A., Desmond, Patricia M., Lui, Elaine, Kwan, Patrick, O’Brien, Terence J.

“…Objective The posterior cingulate cortex (PCC)/precuneus is a key hub of the default mode network, whose function is known to be altered in epilepsy. Glutamate…”
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Gut Microbiota and Epilepsy: A Systematic Review on Their Relationship and Possible Therapeutics by Arulsamy, Alina, Tan, Qian Ying, Balasubramaniam, Vinod, O’Brien, Terence J, Shaikh, Mohd. Farooq

“…Dysbiosis of gut microbiota may lead to a range of diseases including neurological disorders. Thus, it is hypothesized that regulation of the intestinal…”
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Mortality in patients with psychogenic nonepileptic seizures by Nightscales, Russell, McCartney, Lara, Auvrez, Clarissa, Tao, Gerard, Barnard, Sarah, Malpas, Charles B., Perucca, Piero, McIntosh, Anne, Chen, Zhibin, Sivathamboo, Shobi, Ignatiadis, Sophia, Jones, Simon, Adams, Sophia, Cook, Mark J., Kwan, Patrick, Velakoulis, Dennis, D'Souza, Wendyl, Berkovic, Samuel F., O'Brien, Terence J.

“…OBJECTIVETo investigate the hypothesis that patients diagnosed with psychogenic nonepileptic seizures (PNES) on video-EEG monitoring (VEM) have increased…”
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