Search Results - "Nyunt, Myaing M."
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Reduced susceptibility of Plasmodium falciparum to artesunate in southern Myanmar
Published in PloS one (08-03-2013)“…Plasmodium falciparum resistance to artemisinins, the first line treatment for malaria worldwide, has been reported in western Cambodia. Resistance is…”
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2
An improved nucleic acid extraction method from dried blood spots for amplification of Plasmodium falciparum kelch13 for detection of artemisinin resistance
Published in Malaria journal (11-06-2019)“…Mutational analysis of the Plasmodium falciparum kelch 13 (k13) gene is routinely performed to track the emergence and spread of artemisinin resistance…”
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3
A novel method for extracting nucleic acids from dried blood spots for ultrasensitive detection of low-density Plasmodium falciparum and Plasmodium vivax infections
Published in Malaria journal (18-09-2017)“…Greater Mekong Subregion countries are committed to eliminating Plasmodium falciparum malaria by 2025. Current elimination interventions target infections at…”
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4
Antibody signatures of asymptomatic Plasmodium falciparum malaria infections measured from dried blood spots
Published in Malaria journal (23-09-2021)“…Background Screening malaria-specific antibody responses on protein microarrays can help identify immune factors that mediate protection against malaria…”
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No evidence of amplified Plasmodium falciparum plasmepsin II gene copy number in an area with artemisinin-resistant malaria along the China-Myanmar border
Published in Malaria journal (14-09-2020)“…The emergence and spread of artemisinin resistance in Plasmodium falciparum poses a threat to malaria eradication, including China's plan to eliminate malaria…”
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6
An In Silico Analysis of Malaria Pre-Erythrocytic-Stage Antigens Interpreting Worldwide Genetic Data to Suggest Vaccine Candidate Variants and Epitopes
Published in Microorganisms (Basel) (25-05-2022)“…Failure to account for genetic diversity of antigens during vaccine design may lead to vaccine escape. To evaluate the vaccine escape potential of antigens…”
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Asymptomatic Plasmodium falciparum malaria in pregnant women in the Chittagong Hill Districts of Bangladesh
Published in PloS one (23-05-2014)“…Pregnancy is a known risk factor for malaria which is associated with increased maternal and infant mortality and morbidity in areas of moderate-high malaria…”
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Subclinical Plasmodium falciparum infections act as year-round reservoir for malaria in the hypoendemic Chittagong Hill districts of Bangladesh
Published in International journal of infectious diseases (01-08-2016)“…Graphical abstract…”
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9
Mobile phones improve case detection and management of malaria in rural Bangladesh
Published in Malaria journal (04-02-2013)“…The recent introduction of mobile phones into the rural Bandarban district of Bangladesh provided a resource to improve case detection and treatment of…”
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10
A Single Mutation in K13 Predominates in Southern China and Is Associated With Delayed Clearance of Plasmodium falciparum Following Artemisinin Treatment
Published in The Journal of infectious diseases (15-11-2015)“…Background. Artemisinin resistance in Plasmodium falciparum has emerged in Southeast Asia and poses a threat to malaria control and elimination. Mutations in a…”
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Understanding Spatiotemporal Human Mobility Patterns for Malaria Control Using a Multiagent Mobility Simulation Model
Published in Clinical infectious diseases (08-02-2023)“…Abstract Background More details about human movement patterns are needed to evaluate relationships between daily travel and malaria risk at finer scales. A…”
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Artemisinin-Resistant Plasmodium falciparum in Africa
Published in The New England journal of medicine (20-07-2017)“…To the Editor: Lu et al. (March 9 issue) 1 report on an artemisinin-resistant Plasmodium falciparum strain in Africa. We advise caution. Blood levels of…”
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Efavirenz-Based Antiretroviral Therapy Reduces Artemether–Lumefantrine Exposure for Malaria Treatment in HIV-Infected Pregnant Women
Published in Journal of acquired immune deficiency syndromes (1999) (01-02-2020)“…The choice of malaria treatment for HIV-infected pregnant women receiving efavirenz-based antiretroviral therapy must consider the potential impact of drug…”
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Artemether-Lumefantrine Pharmacokinetics and Clinical Response Are Minimally Altered in Pregnant Ugandan Women Treated for Uncomplicated Falciparum Malaria
Published in Antimicrobial agents and chemotherapy (01-03-2016)“…Artemether-lumefantrine is a first-line regimen for the treatment of uncomplicated malaria during the second and third trimesters of pregnancy. Previous…”
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Temporal and Spatial Differences between Symptomatic and Asymptomatic Malaria Infections in the Chittagong Hill Districts, Bangladesh
Published in The American journal of tropical medicine and hygiene (14-12-2022)“…Mapping asymptomatic malaria infections, which contribute to the transmission reservoir, is important for elimination programs. This analysis compared the…”
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16
An ultrasensitive reverse transcription polymerase chain reaction assay to detect asymptomatic low-density Plasmodium falciparum and Plasmodium vivax infections in small volume blood samples
Published in Malaria journal (23-12-2015)“…Highly sensitive, scalable diagnostic methods are needed to guide malaria elimination interventions. While traditional microscopy and rapid diagnostic tests…”
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Genomic structure and diversity of Plasmodium falciparum in Southeast Asia reveal recent parasite migration patterns
Published in Nature communications (17-06-2019)“…Estimates of Plasmodium falciparum migration may inform strategies for malaria elimination. Here we elucidate fine-scale parasite population structure and…”
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Prevalence of Clinical and Subclinical Plasmodium falciparum and Plasmodium vivax Malaria in Two Remote Rural Communities on the Myanmar-China Border
Published in The American journal of tropical medicine and hygiene (01-11-2017)“…Malaria infections may be symptomatic, leading to treatment, or "asymptomatic," typically detected through active surveillance, and not leading to treatment…”
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Temporal Dynamics of Subclinical Malaria in Different Transmission Zones of Myanmar
Published in The American journal of tropical medicine and hygiene (01-09-2022)“…Countries in the Greater Mekong Subregion have committed to eliminate Plasmodium falciparum malaria by 2025. Subclinical malaria infections that can be…”
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Artemether-Lumefantrine and Dihydroartemisinin-Piperaquine Retain High Efficacy for Treatment of Uncomplicated Plasmodium falciparum Malaria in Myanmar
Published in The American journal of tropical medicine and hygiene (01-03-2020)“…The emergence of artemisinin-resistant in the Greater Mekong Subregion threatens both the efficacy of artemisinin-based combination therapy (ACT), the…”
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