Search Results - "Nyman, J. S."

Changes in skeletal collagen cross-links and matrix hydration in high- and low-turnover chronic kidney disease by Allen, M. R., Newman, C. L., Chen, N., Granke, M., Nyman, J. S., Moe, S. M.

“…Summary Chronic kidney disease (CKD) increases fracture risk. The results of this work point to changes in bone collagen and bone hydration as playing a role…”
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Determining the pharmacologic window of bisphosphonates that mitigates severe injury-induced osteoporosis and muscle calcification, while preserving fracture repair by Saito, M., Moore-Lotridge, S. N., Uppuganti, S., Egawa, S., Yoshii, T., Robinette, J. P., Posey, S. L., Gibson, B. H. Y., Cole, H. A., Hawley, G. D., Guelcher, S. A., Tanner, S. B., McCarthy, J. R., Nyman, J. S., Schoenecker, J. G.

“…Summary Following severe injury, biomineralization is disrupted and limited therapeutic options exist to correct these pathologic changes. This study utilized…”
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Technical note: Recommendations for a standard procedure to assess cortical bone at the tissue-level in vivo using impact microindentation by Diez-Perez, A, Bouxsein, M L, Eriksen, E F, Khosla, S, Nyman, J S, Papapoulos, S, Tang, S Y

“…Impact microindentation is a novel method for measuring the resistance of cortical bone to indentation in patients. Clinical use of a handheld impact…”
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Inhibition of vascular endothelial growth factor in young adult mice causes low bone blood flow and bone strength with no effect on bone mass in trabecular regions by Lane, N E, Nyman, J S, Uppuganti, S, Chaudhari, A J, Aguirre, J I, Shidara, K, Liu, X P, Yao, W, Kimmel, D B

“…To determine the effect of an antibody to vascular endothelial growth factor (VEGF) on bone blood flow, bone strength, and bone mass in the young adult mouse…”
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A theoretical analysis of long-term bisphosphonate effects on trabecular bone volume and microdamage by Nyman, Jeffry S., Yeh, Oscar C., Hazelwood, Scott J., Martin, R.Bruce

“…Bisphosphonates increase bone mass and reduce fracture risk, but their anti-resorptive action may lead to increases in fatigue microdamage. To investigate how…”
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Normal Science and Mobility Instruction by Nyman, J.S., Mettler, R.

“…This article contends that the ongoing debate about the necessity of vision in teaching cane travel is misguided. The debate as traditionally framed is…”
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Long stemmed total knee arthroplasty with interlocking screws: a computational bone adaptation study by Nyman, Jeffry S, Hazelwood, Scott J, Rodrigo, Juan J, Martin, R.Bruce, Yeh, Oscar C

“…The ability of an interlocking screw fixation technique to minimize bone loss related to stress shielding in the tibia was investigated and compared to the…”
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The effects of rhBMP-2 released from biodegradable polyurethane/microsphere composite scaffolds on new bone formation in rat femora by Li, Bing, Yoshii, Toshitaka, Hafeman, Andrea E, Nyman, Jeffry S, Wenke, Joseph C, Guelcher, Scott A

“…Abstract Scaffolds prepared from biodegradable polyurethanes (PUR) have been investigated as a supportive matrix and delivery system for skin, cardiovascular,…”
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Measurements of mobile and bound water by nuclear magnetic resonance correlate with mechanical properties of bone by Nyman, Jeffry S, Ni, Qingwen, Nicolella, Daniel P, Wang, Xiaodu

“…Abstract Since clinical measures of bone mineral density do not necessarily predict whether a person will fracture a bone without an intervention, there is a…”
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Type 1 Diabetes in Young Rats Leads to Progressive Trabecular Bone Loss, Cessation of Cortical Bone Growth, and Diminished Whole Bone Strength and Fatigue Life by Silva, Matthew J, Brodt, Michael D, Lynch, Michelle A, McKenzie, Jennifer A, Tanouye, Kristi M, Nyman, Jeffry S, Wang, Xiaodu

“…People with diabetes have increased risk of fracture disproportionate to BMD, suggesting reduced material strength (quality). We quantified the skeletal…”
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Differential effects between the loss of MMP‐2 and MMP‐9 on structural and tissue‐level properties of bone by Nyman, Jeffry S, Lynch, Conor C, Perrien, Daniel S, Thiolloy, Sophie, O'Quinn, Elizabeth C, Patil, Chetan A, Bi, Xiaohong, Pharr, George M, Mahadevan‐Jansen, Anita, Mundy, Gregory R

“…Matrix metalloproteinases (MMPs) are capable of processing certain components of bone tissue, including type 1 collagen, a determinant of the biomechanical…”
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Effect of mixing method on selected properties of acrylic bone cement by Lewis, Gladius, Nyman, Jeffry S., Trieu, Hai H.

“…The present study was an investigation of the effect of the method of mixing the constituents of CMW™3 bone cement on selected physical and mechanical…”
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Total knee replacement with interlocking stems: a preliminary report by Rodrigo, J J, Hazelwood, S J, Farver, T B, Nyman, J S

“…Revision total knee replacements or primary total knee replacements with large amounts of bone loss frequently require long-stemmed prostheses to stabilize the…”
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Local Low-Dose Lovastatin Delivery Improves the Bone-Healing Defect Caused by Loss of Function in Osteoblasts by WEIXI WANG, NYMAN, Jeffry S, MOSS, Heather E, GUTIERREZ, Gloria, MUNDY, Gregory R, XIANGLI YANG, ELEFTERIOU, Florent

“…Postfracture tibial nonunion (pseudoarthrosis) leads to lifelong disability in patients with neurofibromatosis type I (NF1), a disorder caused by mutations in…”
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Congruence of Counselor Self-Disclosure and Perceived Effectiveness by Nyman, Scott J., Daugherty, Timothy K.

“…Sixty-seven college students rated a counselor on expertness, trustworthiness, and attractiveness based on reading 1 of 2 randomly assigned session…”
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Age-related effect on the concentration of collagen crosslinks in human osteonal and interstitial bone tissue by Nyman, Jeffry S., Roy, Anuradha, Acuna, Rae L., Gayle, Heather J., Reyes, Michael J., Tyler, Jerrod H., Dean, David D., Wang, Xiaodu

“…Collagen crosslinks are important to the quality of bone and may be contributors to the age-related increase in bone fracture. This study was performed to…”
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Silent Information Regulator (Sir)T1 Inhibits NF- theta B Signaling to Maintain Normal Skeletal Remodeling by Edwards, J R, Perrien, D S, Fleming, N, Nyman, J S, Ono, K, Connelly, L, Moore, M M, Lwin, ST, Yull, F E, Mundy, G R, Elefteriou, F

“…Silent information regulator T1 (SirT1) is linked to longevity and negatively controls NF- Kappa B signaling, a crucial mediator of survival and regulator of…”
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Transdermal Lovastatin Enhances Fracture Repair in Rats by Gutierrez, Gloria E, Edwards, James R, Garrett, Ian R, Nyman, Jeffry S, McCluskey, Brandon, Rossini, Gianni, Flores, Alda, Neidre, Daria B, Mundy, Gregory R

“…Statins have been shown to stimulate BMP2 transcription and bone formation. This raises the possibility that they could be useful for enhancing rates of…”
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A sustained release of lovastatin from biodegradable, elastomeric polyurethane scaffolds for enhanced bone regeneration by Yoshii, Toshitaka, Hafeman, Andrea E, Nyman, Jeffry S, Esparza, Javier M, Shinomiya, Kenichi, Spengler, Dan M, Mundy, Gregory R, Gutierrez, Gloria E, Guelcher, Scott A

“…Scaffolds prepared from biodegradable polyurethanes (PUR) have been investigated as a supportive matrix and delivery system for skin, cardiovascular, and bone…”
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A new method of determining the J-integral fracture toughness of very tough polymers: application to ultra high molecular weight polyethylene by Lewis, G, Nyman, J S

“…The thrust of the present work was the development of a new modification to the ASTM E813-89 method for determining the J-integral fracture toughness, JIc, of…”
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