Search Results - "Nylund, Marjo"

Serum glial fibrillary acidic protein correlates with multiple sclerosis disease severity by Högel, Heidi, Rissanen, Eero, Barro, Christian, Matilainen, Markus, Nylund, Marjo, Kuhle, Jens, Airas, Laura

“…Background: Cerebrospinal fluid (CSF) levels of two soluble biomarkers, glial fibrillary acidic protein (GFAP) and neurofilament light chain (NfL), have been…”
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Evaluation of Microglial Activation in Multiple Sclerosis Patients Using Positron Emission Tomography by Airas, Laura, Nylund, Marjo, Rissanen, Eero

“…Understanding the mechanisms underlying progression in multiple sclerosis (MS) is one of the key elements contributing to the identification of appropriate…”
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Sex-driven variability in TSPO-expressing microglia in MS patients and healthy individuals by Laaksonen, Sini, Saraste, Maija, Nylund, Marjo, Hinz, Rainer, Snellman, Anniina, Rinne, Juha, Matilainen, Markus, Airas, Laura

“…Males with multiple sclerosis (MS) have a higher risk for disability progression than females, but the reasons for this are unclear. We hypothesized that…”
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Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis by Sucksdorff, Marcus, Matilainen, Markus, Tuisku, Jouni, Polvinen, Eero, Vuorimaa, Anna, Rokka, Johanna, Nylund, Marjo, Rissanen, Eero, Airas, Laura

“…Overactivation of microglia is associated with most neurodegenerative diseases. In this study we examined whether PET-measurable innate immune cell activation…”
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Impact of natalizumab on chronic active lesions (P11-3.011) by Nylund, Marjo, Matilainen, Markus, Sucksdorff, Marcus, Polvinen, Eero, Airas, Laura

“…Abstract only…”
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A Combined Lesion Distribution Parameter Predicts Disease Progression in Multiple Sclerosis (S26.005) by Polvinen, Eero, Matilainen, Markus, Nylund, Marjo, Sucksdorff, Marcus, Airas, Laura

“…Abstract only…”
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Phenotyping Of Multiple Sclerosis Lesions According To Innate Immune Cell Activation Using TSPO-PET (S26.003) by Nylund, Marjo, Sucksdorff, Marcus, Matilainen, Markus, Polvinen, Eero, Tuisku, Jouni, Airas, Laura

“…Abstract only…”
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PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report by Lehto, Jussi, Sucksdorff, Marcus, Nylund, Marjo, Raitanen, Roope, Matilainen, Markus, Airas, Laura

“…Objectives To evaluate the effects of rituximab treatment on innate immune cell activation in primary progressive multiple sclerosis (PPMS). Methods A…”
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Drug reaction with eosinophilia and systemic symptoms after ocrelizumab therapy by Nylund, Marjo, Vuorinen, Tytti, Airas, Laura

“…•Drug reaction with eosinophilia and systemic symptoms (DRESS) occurs rarely with biological drugs.•DRESS-related symptoms include fever, cutaneous eruption,…”
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Longitudinal stability of progression‐related microglial activity during teriflunomide treatment in patients with multiple sclerosis by Lehto, Jussi, Nylund, Marjo, Matilainen, Markus, Sucksdorff, Marcus, Vuorimaa, Anna, Rajander, Johan, Wahlroos, Saara, Hariri, Parisa, Airas, Laura

“…Background and purpose The aim was to study brain innate immune cell activation in teriflunomide‐treated patients with relapsing–remitting multiple sclerosis…”
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Rituximab in the treatment of multiple sclerosis in the Hospital District of Southwest Finland by Airas, Laura, Nylund, Marjo, Mannonen, Iina, Matilainen, Markus, Sucksdorff, Marcus, Rissanen, Eero

“…•We report our experiences of off-label rituximab treatment among 72 MS patients at the Hospital District of Southwest Finland.•Rituximab treatment was chosen…”
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Serum GFAP Associates with Neurofilament Light and Disease Severity in Late Multiple Sclerosis (P5.2-017) by Airas, Laura, Hoegel, Heidi, Rissanen, Eero, Matilainen, Markus, Nylund, Marjo, Kuhle, Jens

“…Abstract only…”
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Phenotyping of multiple sclerosis lesions according to innate immune cell activation using 18 kDa translocator protein-PET by Nylund, Marjo, Sucksdorff, Marcus, Matilainen, Markus, Polvinen, Eero, Tuisku, Jouni, Airas, Laura

“…Abstract Chronic active lesions are promotors of neurodegeneration and disease progression in multiple sclerosis. They harbour a dense rim of activated innate…”
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TSPO-Detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis by Polvinen, Eero, Matilainen, Markus, Nylund, Marjo, Sucksdorff, Marcus, Airas, Laura M

“…In the multiple sclerosis (MS) brain, chronic active lesions can be detected using MRI- and PET-based methods. In this study, we investigated whether the…”
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Innate Immune Cell–Related Pathology in the Thalamus Signals a Risk for Disability Progression in Multiple Sclerosis by Misin, Olavi, Matilainen, Markus, Nylund, Marjo, Honkonen, Eveliina, Rissanen, Eero, Sucksdorff, Marcus, Airas, Laura

“…Our aim was to investigate whether 18-kDa translocator protein (TSPO) radioligand binding in gray matter (GM) predicts later disability progression in multiple…”
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Natalizumab treatment reduces microglial activation in the white matter of the MS brain by Sucksdorff, Marcus, Tuisku, Jouni, Matilainen, Markus, Vuorimaa, Anna, Smith, Sarah, Keitilä, Joonas, Rokka, Johanna, Parkkola, Riitta, Nylund, Marjo, Rinne, Juha, Rissanen, Eero, Airas, Laura

“…OBJECTIVETo evaluate whether natalizumab treatment reduces microglial activation in MS. METHODSWe measured microglial activation using the 18-kDa translocator…”
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Frequency and etiology of acute transverse myelitis in Southern Finland by Smith, Emma, Jaakonmäki, Nina, Nylund, Marjo, Kupila, Laura, Matilainen, Markus, Airas, Laura

“…•We found an annual frequency of 1:100 000 for acute transverse myelitis.•A disease-specific etiology could be established after re-evaluation of the cohort in…”
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Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging by Bezukladova, Svetlana, Tuisku, Jouni, Matilainen, Markus, Vuorimaa, Anna, Nylund, Marjo, Smith, Sarah, Sucksdorff, Marcus, Mohammadian, Mehrbod, Saunavaara, Virva, Laaksonen, Sini, Rokka, Johanna, Rinne, Juha O., Rissanen, Eero, Airas, Laura

“…To evaluate in vivo the co-occurrence of microglial activation and microstructural white matter (WM) damage in the MS brain and to examine their association…”
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Drug reaction with eosinophilia and systemic symptoms after ocrelizumab therapy by Nylund, Marjo, Vuorinen, Tytti, Airas, Laura

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PET-measurable innate immune cell activation reduction in chronic active lesions in PPMS brain after rituximab treatment: a case report by Lehto, Jussi, Sucksdorff, Marcus, Nylund, Marjo, Raitanen, Roope, Matilainen, Markus, Airas, Laura

“…OBJECTIVESTo evaluate the effects of rituximab treatment on innate immune cell activation in primary progressive multiple sclerosis (PPMS). METHODSA…”
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