Use of psychiatric medications in schizophrenia and other psychoses in a general population sample

Use of psychiatric medications in schizophrenia and other psychoses in a general population sample

Abstract The information on the use of psychiatric medications in general population-based samples is limited. Our aim was to analyse the use of psychiatric medications and factors associated with antipsychotic use in psychoses in a general population sample. Fifty-five persons with schizophrenia, 2...

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Published in:Psychiatry research Vol. 235; pp. 160 - 168
Main Authors: Nykänen, Salla, Puska, Virpi, Tolonen, Jussi-Pekka, Salo, Henri, Isohanni, Matti, Koponen, Hannu, Pirkola, Sami, Penttilä, Matti, Haapea, Marianne, Moilanen, Jani, Miettunen, Jouko, Jääskeläinen, Erika
Format: Journal Article
Language:English
Published: Ireland Elsevier Ireland Ltd 30-01-2016
Subjects:
Adult
Antidepressive Agents - therapeutic use
Antipsychotic
Antipsychotic Agents - therapeutic use
Benzodiazepines - therapeutic use
Bipolar Disorder - drug therapy
Cohort Studies
Depressive Disorder, Major - drug therapy
Educational Status
Female
Finland - epidemiology
Follow-up
Humans
Male
Medication
Predictor
Psychiatry
Psychosis
Psychotic Disorders - drug therapy
Schizophrenia - drug therapy
Sex Factors
Treatment
Finland
Psychosis
Medication
Antipsychotic
Treatment
Predictor
Follow-up
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Summary:Abstract The information on the use of psychiatric medications in general population-based samples is limited. Our aim was to analyse the use of psychiatric medications and factors associated with antipsychotic use in psychoses in a general population sample. Fifty-five persons with schizophrenia, 21 with bipolar psychosis or psychotic depression and 20 with other psychoses from the Northern Finland Birth Cohort 1966 were examined at about 43 years of age. The frequency of use and dosage of psychiatric medication and the factors associated with the use of antipsychotics were analysed. Antipsychotics were used by 85% of schizophrenia, 65% of bipolar psychosis or psychotic depression and 62% of other psychoses cases; antidepressants were used by 22%, 60% and 33%; and benzodiazepines by 42%, 35% and 10%, respectively. In all the diagnostic groups, higher symptom scores and a higher number of hospital days were associated with the use of antipsychotics. In schizophrenia and other psychoses, poorer social and occupational functioning, and in other psychoses, female gender and lower education were also associated with the use of antipsychotics. Our results may partly indicate that, especially in schizophrenia, the effectiveness of antipsychotics is not as good as expected.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0165-1781
1872-7123
DOI:10.1016/j.psychres.2015.11.013