Search Results - "Nye, P C"

Intracellular pH and its regulation in isolated type I carotid body cells of the neonatal rat by Buckler, K J, Vaughan‐Jones, R D, Peers, C, Nye, P C

“…1. The dual-emission pH-sensitive fluoroprobe carboxy-SNARF-1 (carboxy-seminaptharhodofluor) was used to measure pHi in type I cells enzymically dispersed from…”
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Effects of extracellular pH, PCO2 and HCO3- on intracellular pH in isolated type-I cells of the neonatal rat carotid body by Buckler, K J, Vaughan‐Jones, R D, Peers, C, Lagadic‐Gossmann, D, Nye, P C

“…1. The effects of changing PCO2 extracellular pH (pHo) and HCO3- on intracellular pH (pHi) were studied in isolated neonatal rat type-I carotid body cells…”
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Effects of potassium, oxygen and carbon dioxide on the steady-state discharge of cat carotid body chemoreceptors by Burger, R E, Estavillo, J A, Kumar, P, Nye, P C, Paterson, D J

“…1. We have studied the effects of intravenous infusions of 0.1 mmol/min KCl (raising arterial potassium from ca. 3.2 to 6.0 mM) on the steady-state responses…”
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Do oxygen tension variations contribute to the respiratory oscillations of chemoreceptor discharge in the cat? by Kumar, P, Nye, P C, Torrance, R W

“…1. A high-frequency high-flow ventilator has been developed which will produce abrupt changes in alveolar gas tensions. We have used it to study the individual…”
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Phenoxybenzamine is more effective and less harmful than papaverine in the prevention of radial artery vasospasm by Dipp, M.A., Nye, P.C.G., Taggart, D.P.

“…Objectives: There is an increasing use of arterial conduits for coronary artery bypass grafting, and the radial artery is commonly used as the third graft. The…”
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Inhibition of nitric oxide synthesis potentiates hypoxic vasoconstriction in isolated rat lungs by Robertson, B E, Warren, J B, Nye, P C

“…We have investigated the influence of endogenous nitric oxide (NO) on the vascular resistance of isolated rat lungs by inhibiting its synthesis with the false…”
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Effect of waveforms of inspired gas tension on the respiratory oscillations of carotid body discharge by Kumar, P, Nye, P C, Torrance, R W

“…The responses of carotid body chemoreceptor discharge to repeated ramps (20- to 60-s forcing cycle durations) of inspired gas tensions were studied in…”
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Tolbutamide reverses hypoxic pulmonary vasoconstriction in isolated rat lungs by Robertson, B E, Paterson, D J, Peers, C, Nye, P C

“…We have investigated the effects of tolbutamide on the hypoxic vasoconstriction of isolated, perfused rat lungs. We did this because lowered ATP may link…”
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The location of carbonic anhydrase in relation to the blood-brain barrier at the medullary chemoreceptors of the cat by Hanson, M A, Nye, P C, Torrance, R W

“…1. The role of carbonic anhydrase near the medullary chemoreceptors has been investigated in the cat. Vertebral artery injections have been used to cause…”
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The reflex respiratory effects on cats of breathing through a tube by Marsh, J, Nye, P C

“…1. In anaesthetized cats, breathing air through an external dead space (a tube, 20-40 ml.) stimulated ventilation in excess of that expected from the end-tidal…”
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Effect of potassium on ventilation in the rhesus monkey by Paterson, D J, Dorrington, K L, Bergel, D H, Kerr, G, Miall, R C, Stein, J F, Nye, P C

“…Increasing the concentration of arterial plasma K+ to 6-8 mM increased ventilation in two sedated analgesic-treated rhesus monkeys who had their end-tidal CO2…”
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Studies on the localization of pulmonary carbonic anhydrase in the cat by Hanson, M A, Nye, P C, Torrance, R W

“…1. We considered whether some of the carbonic anhydrase of the lung is on the surface of the pulmonary capillaries so that it acts directly on plasma as it…”
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Nitric oxide and prostaglandin pathways interact in the regulation of hypercapnic cerebral vasodilatation by HEINERT, G, NYE, P. C. G, PATERSON, D. J

“…To test whether nitric oxide and prostaglandin pathways interact in hypercapnic cerebral vasodilatation, cerebral blood flow (CBF) was measured in enflurane…”
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Ca2+ and Mg-ATP activated potassium channels from rat pulmonary artery by Robertson, B E, Corry, P R, Nye, P C, Kozlowski, R Z

“…We have observed a novel class of calcium-activated potassium channel which is activated by physiological levels of intracellular ATP. These KCa,ATP channels…”
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Proportional sensitivity of arterial chemoreceptors to CO2 by Kumar, P, Nye, P C, Torrance, R W

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Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle by Dipp, M, Nye, P C, Evans, A M

“…The hypoxic constriction of isolated pulmonary vessels is composed of an initial transient phase (phase 1) followed by a slowly developing increase in tone…”
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Ligustrazine selectively blocks ATP-sensitive K + channels in mouse pancreatic β cells by Peers, C., Smith, P.A., Nye, P.C.G.

“…Ligustrazine potently inhibits hypoxic pulmonary vasoconstriction. This effect can be mimicked by the sulphonylurea tolbutamide, a blocker of ATP-sensitive K +…”
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The modulation of intracellular pH in carotid body glomus cells by extracellular pH and pCO2 by Buckler, K J, Vaughan-Jones, R D, Peers, C, Lagadic-Gossmann, D, Nye, P C

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Regulation of intracellular pH in type I cells of the neonatal rat carotid body by Vaughan-Jones, R D, Buckler, K J, Peers, C, Nye, P C

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The effect of hypoxia on plasma potassium concentration and the excitation of arterial chemoreceptors in the cat by Paterson, D J, Estavillo, J A, Nye, P C

“…Intra-arterial recordings of potassium concentration ([K+]a) and arterial chemoreceptor discharge were made in six anaesthetized cats while tracheal PO2 was…”
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