Search Results - "Nydam, Thomas"

A phase 2 study of intravenous panobinostat in patients with castration-resistant prostate cancer by Rathkopf, Dana E., Picus, Joel, Hussain, Arif, Ellard, Susan, Chi, Kim Nguyen, Nydam, Thomas, Allen-Freda, Erin, Mishra, Kaushal Kishor, Porro, Maria Grazia, Scher, Howard I., Wilding, George

“…Purpose Panobinostat, a pan-deacetylase inhibitor, increases acetylation of proteins associated with growth and survival of malignant cells. This phase 2 study…”
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Mutations in MHC class II dimer of dimers contact residues: effects on antigen presentation by Nydam, T, Wade, T K, Yadati, S, Gabriel, J L, Barisas, B G, Wade, W F

“…The recent solutions of the MHC class II crystal structure reveal dimerization of the alphabeta heterodimers. These dimer of dimers structures may also exist…”
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P-272 The international, open-label, multicenter phase 2 LAPACT trial of nab-paclitaxel (nab-P) plus gemcitabine (Gem) for patients with locally advanced pancreatic cancer (LAPC) by Pascal, Hammel, Jill, Lacy, Fabienne, Portales, Alberto, Sobrero, Beatriz, García-Paredes, Edward, Kim, Fernando, Rivera, Luis, Manzano Jose, Eric, Terrebonne, Venu, Bathini, Scot, Dowden, Jamil, Asselah, Jack, Shiansong Li, Thomas, Nydam, Louis, Kayitalire, Philip, Philip

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P-272The international, open-label, multicenter phase 2 LAPACT trial of nab-paclitaxel (nab-P) plus gemcitabine (Gem) for patients with locally advanced pancreatic cancer (LAPC) by Pascal, Hammel, Jill, Lacy, Fabienne, Portales, Alberto, Sobrero, Beatriz, Garcia-Paredes, Edward, Kim, Fernando, Rivera, Luis, Manzano Jose, Eric, Terrebonne, Venu, Bathini, Scot, Dowden, Jamil, Asselah, Jack, Shiansong Li, Thomas, Nydam, Louis, Kayitalire, Philip, Philip

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Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled 14C material in advanced cancer patients by Clive, Sally, Woo, Margaret M., Nydam, Thomas, Kelly, Lindsay, Squier, Margaret, Kagan, Mark

“…Purpose Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion…”
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Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled super(14)C material in advanced cancer patients by Clive, Sally, Woo, Margaret M, Nydam, Thomas, Kelly, Lindsay, Squier, Margaret, Kagan, Mark

“…Purpose: Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion…”
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Characterizing the disposition, metabolism, and excretion of an orally active pan-deacetylase inhibitor, panobinostat, via trace radiolabeled ^sup 14^C material in advanced cancer patients by Clive, Sally, Woo, Margaret M, Nydam, Thomas, Kelly, Lindsay, Squier, Margaret, Kagan, Mark

“…Elucidating the metabolic profile of anticancer agent panobinostat is essential during drug development. Disposition, metabolism, and excretion profiles were…”
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Donor preoperative oxygen delivery and post-extubation hypoxia impact donation after circulatory death hypoxic cholangiopathy by Chirichella, Thomas J, Dunham, C Michael, Zimmerman, Michael A, Phelan, Elise M, Mandell, M Susan, Conzen, Kendra D, Kelley, Stephen E, Nydam, Trevor L, Bak, Thomas E, Kam, Igal, Wachs, Michael E

“…AIM: To evaluate donation after circulatory death（DCD） orthotopic liver transplant outcomes [hypoxic cholangiopathy（HC） and patient/graft survival] and donor…”
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Salt bridge residues between I-A k dimer of dimers α-chains modulate antigen presentation by Yadati, Shyam, Nydam, Thomas, Demian, Doug, Wade, Terri K, Gabriel, Jerome L, Barisas, B.George, Wade, William F

“…Class II dimers of dimers are predicted to have functional significance in antigen presentation. The putative contact amino acids of the I-A k class II dimer…”
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Salt bridge residues between I-Ak dimer of dimers alpha-chains modulate antigen presentation by Yadati, S, Nydam, T, Demian, D, Wade, T K, Gabriel, J L, Barisas, B G, Wade, W F

“…Class II dimers of dimers are predicted to have functional significance in antigen presentation. The putative contact amino acids of the I-Ak class II dimer of…”
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