Search Results - "Nyce, Mark R."

New concepts in the pathophysiology of inflammatory bowel disease by BAMIAS, Giorgos, NYCE, Mark R, DE LA RUE, Sarah A, COMINELLI, Fabio

“…The inflammatory bowel diseases (IBDs), that is, Crohn disease and ulcerative colitis, affect approximately 1 million persons in North America and several…”
Get full text

Serum immunoreactive-leptin concentrations in normal-weight and obese humans by Considine, R.V, Sinha, M.K, Heiman, M.L, Kriauciunas, A, Stephens, T.W, Nyce, M.R, Ohannesian, J.P, Marco, C.C, McKee, L.J, Bauer, T.L

“…Background. Leptin, the product of the ob gene, is a hormone secreted by adipocytes. Animals with mutations in the ob gene are obese and lose weight when given…”
Get full text

Acute and chronic effect of insulin on leptin production in humans : Studies in vivo and in vitro by KOLACZYNSKI, J. W, NYCE, M. R, CONSIDINE, R. V, BODEN, G, NOLAN, J. J, HENRY, R, MUDALIAR, S. R, OLEFSKY, J, CARO, J. F

“…This study was undertaken to investigate the changes in obesity (OB) gene expression and production of leptin in response to insulin in vitro and in vivo under…”
Get full text

Decreased cerebrospinal-fluid/serum leptin ratio in obesity: a possible mechanism for leptin resistance by Caro, J F, Kolaczynski, J W, Nyce, M R, Ohannesian, J P, Opentanova, I, Goldman, W H, Lynn, R B, Zhang, P L, Sinha, M K, Considine, R V

“…A receptor for leptin has been cloned from the choroid plexus, the site of cerebrospinal-fluid (CSF) production and the location of the…”
Get more information

Effect of troglitazone on leptin production : Studies in vitro and in human subjects by NOLAN, J. J, OLEFSKY, J. M, NYCE, M. R, CONSIDINE, R. V, CARO, J. F

“…Leptin, the product of the ob gene, is a hormone secreted by adipocytes. Animals with mutations in the ob gene are obese and lose weight when given leptin, but…”
Get full text

Responses of leptin to short-term fasting and refeeding in humans : A link with ketogenesis but not ketones themselves by KOLACZYNSKI, J. W, CONSIDINE, R. V, OHANNESIAN, J, MARCO, C, OPENTANOVA, I, NYCE, M. R, MYINT, M, CARO, J. F

“…We investigated the response of leptin to short-term fasting and refeeding in humans. A mild decline in subcutaneous adipocyte ob gene mRNA and a marked fall…”
Get full text

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity by Considine, R V, Considine, E L, Williams, C J, Nyce, M R, Magosin, S A, Bauer, T L, Rosato, E L, Colberg, J, Caro, J F

“…Obese (ob) gene expression in abdominal subcutaneous adipocytes from lean and obese humans was examined. The full coding region of the ob gene was isolated…”
Get full text

Protein kinase C is increased in the liver of humans and rats with non-insulin-dependent diabetes mellitus: an alteration not due to hyperglycemia by Considine, R V, Nyce, M R, Allen, L E, Morales, L M, Triester, S, Serrano, J, Colberg, J, Lanza-Jacoby, S, Caro, J F

“…We tested the hypothesis that liver protein kinase C (PKC) is increased in non-insulin-dependent diabetes mellitus (NIDDM). To this end we examined the…”
Get full text

Dexamethasone stimulates leptin release from human adipocytes: Unexpected inhibition by insulin by Considine, Robert V., Nyce, Mark R., Kolaczynski, Jerzy W., Zhang, Pei Li, Ohannesian, Joanna P., Moore Jr, John H., Fox, James W., Caro, José F.

“…In the present study we have examined the effect of dexamethasone on ob gene mRNA expression and leptin release from isolated human subcutaneous adipocytes…”
Get full text

Mutation Screening and Identification of a Sequence Variation in the Human OB Gene Coding Region by Considine, Robert V., Considine, Eileen L., Williams, Charlene J., Nyce, Mark R., Zhang, Peili, Opentanova, Irina, Ohannesian, Joanna P., Kolaczynski, Jerzy W., Bauer, Thomas L., Moore, John H., Caro, Jose F.

“…In the present study mRNA from the subcutaneous adipose tissue of 68 obese (defined as a body mass index ≥27.3 for men and ≥27.8 for women) and 38 lean…”
Get full text

Paracrine stimulation of preadipocyte-enriched cell cultures by mature adipocytes by Considine, R V, Nyce, M R, Morales, L M, Magosin, S A, Sinha, M K, Bauer, T L, Rosato, E L, Colberg, J, Caro, J F

“…We developed a double-chamber system in which to examine the effects of mature adipocytes on the growth and differentiation of preadipocytes and other cells in…”
Get full text

Responses of leptin to short-term fasting and refeeding in humans: a link with keotgenesis but not ketones themselves by Kolaczynski, Jerzy W, Considine, Robert V, Ohannesian, Joanna, Marco, Cheryl, Opentanova, Irina, Nyce, Mark R, Myint, Michael, Caro, Jose F

Get full text