Search Results - "Nyborg, J."

The HTLV-1 tax protein cooperates with phosphorylated CREB, TORC2 and p300 to activate CRE-dependent cyclin D1 transcription by Kim, Y-M, Geiger, T R, Egan, D I, Sharma, N, Nyborg, J K

“…Adult T-cell leukemia/lymphoma is a fatal malignancy etiologically linked to infection with the human T-cell leukemia virus (HTLV-1). The virally encoded…”
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The Oncoprotein Tax Binds the SRC-1-Interacting Domain of CBP/p300 To Mediate Transcriptional Activation by Scoggin, Kirsten E. S., Ulloa, Aida, Nyborg, Jennifer K.

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Zinc-Binding Site of an S100 Protein Revealed. Two Crystal Structures of Ca2+-Bound Human Psoriasin (S100A7) in the Zn2+-Loaded and Zn2+-Free States by Brodersen, D. E, Nyborg, J, Kjeldgaard, M

“…The crystal structure of human psoriasin (S100A7) in the native, calcium-bound form has been determined from two crystal forms of the protein crystallized with…”
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Anchoring of CREB binding protein to the human T-cell leukemia virus type 1 promoter: a molecular mechanism of Tax transactivation by Giebler, Holli A., Loring, Jeanne E., van Orden, Karen, Colgin, Mark A., Garrus, Jennifer E., Escudero, Kenneth W., Brauweiler, Anne, Nyborg, Jennifer K.

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Development of Prostate Bed Delineation Consensus Guidelines for Magnetic Resonance Image-Guided Radiotherapy and Assessment of Its Effect on Interobserver Variability by Sritharan, Kobika, Akhiat, Hafid, Cahill, Declan, Choi, Seungtaek, Choudhury, Ananya, Chung, Peter, Diaz, Juan, Dysager, Lars, Hall, William, Huddart, Robert, Kerkmeijer, Linda G W, Lawton, Colleen, Mohajer, Jonathan, Murray, Julia, Nyborg, Christina J, Pos, Floris J, Rigo, Michele, Schytte, Tine, Sidhom, Mark, Sohaib, Aslam, Tan, Alex, van der Voort van Zyp, Jochem, Vesprini, Danny, Zelefsky, Michael J, Tree, Alison C

“…The use of magnetic resonance imaging (MRI) in radiotherapy planning is becoming more widespread, particularly with the emergence of MRI-guided radiotherapy…”
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p300-Mediated Tax Transactivation from Recombinant Chromatin: Histone Tail Deletion Mimics Coactivator Function by Georges, Sara A., Kraus, W. Lee, Luger, Karolin, Nyborg, Jennifer K., Laybourn, Paul J.

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Applications of single-wavelength anomalous dispersion at high and atomic resolution by Brodersen, D. E., De La Fortelle, E., Vonrhein, C., Bricogne, G., Nyborg, J., Kjeldgaard, M.

“…Two examples of the application of single‐wavelength anomalous dispersion (SAD) in macromolecular structure determination are described, both using the…”
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Mechanism of DNA-binding enhancement by the human T-cell leukaemia virus transactivator Tax by Baranger, Anne M, Palmer, C. Rodgers, Hamm, Mary Kay, Giebler, Holli A, Brauweiler, Anne, Nyborg, Jennifer K, Schepartz, Alanna

“…Tax protein activates transcription of the human T-cell leukaemia virus type I (HTLV-I) genome through three imperfect cyclic AMP-responsive element (CRE)…”
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Identification of 13 new mutations in the vasopressin-neurophysin II gene in 17 kindreds with familial autosomal dominant neurohypophyseal diabetes insipidus by RITTIG, S, ROBERTSON, G. L, SIGGAARD, C, KOVACS, L, GREGERSEN, N, NYBORG, J, PEDERSEN, E. B

“…Familial neurohypophyseal diabetes insipidus (FNDI) is an autosomal dominant disorder characterized by progressive postnatal deficiency of arginine vasopressin…”
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EF-hands at atomic resolution: the structure of human psoriasin (S100A7) solved by MAD phasing by Brodersen, DE, Etzerodt, M, Madsen, P, Celis, JE, Thøgersen, HC, Nyborg, J, Kjeldgaard, M

“…Background: The S100 family consists of small acidic proteins, belonging to the EF-hand class of calcium-binding proteins. They are primarily regulatory…”
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Binding of the human T-cell leukemia virus Tax protein to the coactivator CBP interferes with CBP-mediated transcriptional control by VAN ORDEN, K, YAN, J.-P, ULLOA, A, NYBORG, J. K

“…The HTLV-I oncoprotein Tax is required for high level viral transcription and is strongly linked to HTLV-I-associated malignant transformation. Tax stimulates…”
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Human T-cell Leukemia Virus Type I Tax Repression of p73β Is Mediated through Competition for the C/H1 Domain of CBP by Lemasson, Isabelle, Nyborg, Jennifer K.

“…The Tax protein, encoded by the human T-cell leukemia virus type I (HTLV-I), is required for high level viral transcription and HTLV-I-associated malignant…”
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Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB) by FRANKLIN, A. A, KUBIK, M. F, UITTENBOGAARD, M. N, BRAUWEILER, A, PONGSAK UTAISINCHAROEN, MATTHEWS, M.-A. H, DYNAN, W. S, HOEFFLER, J. P, NYBORG, J. K

“…The human T-cell leukemia virus type I (HTLV-I)-encoded transcriptional activator protein Tax is strongly implicated in HTLV-I pathogenesis. Tax regulates…”
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Transcription Regulatory Complexes Bind the Human T-Cell Leukemia Virus 5′ and 3′ Long Terminal Repeats To Control Gene Expression by Lemasson, Isabelle, Polakowski, Nicholas J., Laybourn, Paul J., Nyborg, Jennifer K.

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Pleiotropic Effect of the Human T-Cell Leukemia Virus Tax Protein on the DNA Binding Activity of Eukaryotic Transcription Factors by Armstrong, Allison P., Franklin, Audrey A., Uittenbogaard, Martine N., Giebler, Holli A., Nyborg, Jennifer K.

“…The Tax protein, encoded by the human T-cell leukemia virus type I, is a potent activator of viral and cellular gene transcription. Tax does not bind DNA…”
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Binding of p53 to the KIX domain of CREB binding protein. A potential link to human T-cell leukemia virus, type I-associated leukemogenesis by Van Orden, K, Giebler, H A, Lemasson, I, Gonzales, M, Nyborg, J K

“…The pleiotropic cellular coactivator CREB binding protein (CBP) plays a critical role in supporting p53-dependent tumor suppressor functions. p53 has been…”
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Transcription Factor Binding and Histone Modifications on the Integrated Proviral Promoter in Human T-cell Leukemia Virus-I-infected T-cells by Lemasson, Isabelle, Polakowski, Nicholas J., Laybourn, Paul J., Nyborg, Jennifer K.

“…The human T-cell leukemia virus (HTLV-I)-encoded Tax protein is a potent transcriptional activator that stimulates expression of the integrated provirus…”
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The ternary complex of aminoacylated tRNA and EF-Tu-GTP. Recognition of a bond and a fold by Nissen, P., Kjeldgaard, M., Thirup, S., Clark, B.F.C., Nyborg, J.

“…The refined crystal structure of the ternary complex of yeast Phe-tRNA Phe, Thermus aquaticus elongation factor EF-Tu and the non-hydrolyzable GTP analog,…”
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Human T-Cell Leukemia Virus Type 1 Tax Requires Direct Access to DNA for Recruitment of CREB Binding Protein to the Viral Promoter by Lenzmeier, Brian A., Giebler, Holli A., Nyborg, Jennifer K.

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p53 Recruitment of CREB Binding Protein Mediated through Phosphorylated CREB: a Novel Pathway of Tumor Suppressor Regulation by Giebler, Holli A., Lemasson, Isabelle, Nyborg, Jennifer K.

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