Search Results - "Nyati, M."

Unintended pregnancy and contraception use among African women living with HIV: Baseline analysis of the multi-country US PEPFAR PROMOTE cohort by Aizire, Jim, Yende-Zuma, Nonhlanhla, Hanley, Sherika, Nematadzira, Teacler, Nyati, Mandisa M, Dadabhai, Sufia, Chinula, Lameck, Nakaye, Catherine, Fowler, Mary Glenn, Taha, Taha

“…About 90% of unintended pregnancies are attributed to non-use of effective contraception-tubal ligation, or reversible effective contraception (REC) including…”
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The multi-country PROMOTE HIV antiretroviral treatment observational cohort in Sub-Saharan Africa: Objectives, design, and baseline findings by Taha, Taha E, Yende-Zuma, Nonhlanhla, Aizire, Jim, Chipato, Tsungai, Wambuzi Ogwang, Lillian, Makanani, Bonus, Chinula, Lameck, Nyati, Mandisa M, Hanley, Sherika, Brummel, Sean S, Fowler, Mary Glenn

“…The PROMOTE study aims to measure long-term antiretroviral treatment (ART) safety and adherence; compare HIV disease progression; assess subsequent adverse…”
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Profiling of cancer cells using protein microarrays: Discovery of novel radiation-regulated proteins by SREEKUMAR, Arun, NYATI, Mukesh K, VARAMBALLY, Sooryanarayana, BARRETTE, Terrence R, GHOSH, Debashis, LAWRENCE, Theodore S, CHINNAIYAN, Arul M

“…The advent of DNA microarray technology will likely have a major impact on the molecular classification and understanding of human cancer. Obtaining a global…”
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Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity by FENG, F. Y, VARAMBALLY, S, TOMLINS, S. A, CHUN, P. Y, LOPEZ, C. A, LI, X, DAVIS, M. A, CHINNAIYAN, A. M, LAWRENCE, T. S, NYATI, M. K

“…We have recently reported that treatment with gemcitabine, a potent chemotherapeutic agent and radiation sensitizer, stimulates phosphorylation of the…”
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Slow Acceptance of Universal Antiretroviral Therapy (ART) Among Mothers Enrolled in IMPAACT PROMISE Studies Across the Globe by Stranix-Chibanda, L., Brummel, S., Pilotto, J., Mutambanengwe, M., Chanaiwa, V., Mhembere, T., Kamateeka, M., Aizire, J., Masheto, G., Chamanga, R., Maluwa, M., Hanley, S., Joao, E., Theron, G., Nevrekar, N., Nyati, M., Santos, B., Aurpibul, L., Mubiana-Mbewe, M., Oliveira, R., Anekthananon, T., Mlay, P., Angelidou, K., Tierney, C., Ziemba, L., Coletti, A., McCarthy, K., Basar, M., Chakhtoura, N., Browning, R., Currier, J., Fowler, M. G., Flynn, P.

“…The PROMISE trial enrolled asymptomatic HIV-infected pregnant and postpartum women not eligible for antiretroviral treatment (ART) per local guidelines and…”
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The potential of 5-fluorocytosine/cytosine deaminase enzyme prodrug gene therapy in an intrahepatic colon cancer model by NYATI, M. K, SYMON, Z, KIEVIT, E, DORNFELD, K. J, RYNKIEWICZ, S. D, ROSS, B. D, REHEMTULLA, A, LAWRENCE, T. S

“…Colorectal cancer can metastasize to the liver, but remain liver confined for years. A critical step in developing treatments for intrahepatic cancer involves…”
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Yeast cytosine deaminase improves radiosensitization and bystander effect by 5-fluorocytosine of human colorectal cancer xenografts by KIEVIT, Els, NYATI, Mukesh K, NG, Emily, STEGMAN, Lauren D, PARSELS, Josh, ROSS, Brian D, REHEMTULLA, Alnawaz, LAWRENCE, Theodore S

“…The efficacy of cancer gene therapy using bacterial cytosine deaminase (bCD)/5-fluorocytosine (5-FC) enzyme/prodrug strategy is limited by the inefficiency of…”
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Effects of long-term antiretroviral therapy in reproductive-age women in sub-Saharan Africa (the PEPFAR PROMOTE study): a multi-country observational cohort study by Taha, Taha E, Yende-Zuma, Nonhlanhla, Brummel, Sean S, Stranix-Chibanda, Lynda, Wambuzi Ogwang, Lillian, Dadabhai, Sufia, Chinula, Lameck, Nyati, Mandisa M, Hanley, Sherika, Makanani, Bonus, Chipato, Tsungai, Atuhaire, Patience, Aizire, Jim, Fowler, Mary Glenn

“…We report the long-term impact of ART in women of reproductive age (15–49 years) in Africa who have been using ART for up to 10 years. We assess outcomes of…”
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High and selective expression of yeast cytosine deaminase under a carcinoembryonic antigen promoter-enhancer by NYATI, Mukesh K, SREEKUMAR, Arun, SHENGPING LI, MING ZHANG, RYNKIEWICZ, Susan D, CHINNAIYAN, Arul M, REHEMTULLA, Alnawaz, LAWRENCE, Theodore S

“…Yeast cytosine deaminase (yCD)-based gene therapy offers the potential for selective production of the cytotoxic and radiosensitizing drug 5-fluorouracil…”
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Unintended pregnancy and contraception use among African women living with HIV: Baseline analysis of the multi-country US PEPFAR PROMOTE cohort by Jim Aizire, Nonhlanhla Yende-Zuma, Sherika Hanley, Teacler Nematadzira, Mandisa M. Nyati, Sufia Dadabhai, Lameck Chinula, Catherine Nakaye, Mary Glenn Fowler, Taha Taha

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Wild-type EGFR Is Stabilized by Direct Interaction with HSP90 in Cancer Cells and Tumors by Ahsan, Aarif, Ramanand, Susmita G, Whitehead, Christopher, Hiniker, Susan M, Rehemtulla, Alnawaz, Pratt, William B, Jolly, Shruti, Gouveia, Christopher, Truong, Kristy, Waes, Carter Van, Ray, Dipankar, Lawrence, Theodore S, Nyati, Mukesh K

“…Abstract The epidermal growth factor receptor (EGFR) has been targeted for inhibition using tyrosine kinase inhibitors and monoclonal antibodies, with…”
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Anticancer activities of 2,3-dihydro-1,4-benzothiazines, and of their 4-(N-alkyl amides) and 4-(N-alkyl N-nitrosoamides) by Gupta, R R, Dev, P K, Sharma, M L, Rajoria, C M, Gupta, A, Nyati, M

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Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial by Bamford, Alasdair, Riault, Yoann, Nolan, Aoife, Morkunaite, Gabija, Kanjanavanit, Suparat, Pavia Ruz, Noris, Niehues, Tim, Ford, Deborah, Gibb, Diana M., Meyer, L., Cagnot, C., Hudson, F., Gao, L., Blackstone, J., Inshaw, J., Nardone, A., Bilardi, D., Chalermpantmetagul, S., Kaewbundit, A., Sripaoraya, W., Kruenual, N., Khamjakkaew, W., Hirt, D., Plonné, D., Noguera, T., Muñoz Fernández, M.A., Mangano, A., Gatto, M., Soria, A., Paredes, E., Rodallec, A., Blaise, N., Neri-Macias, A., Teixeira, C., Fernandes, A., Padrao, A., Correira, C., Tavares, M., Monteiro, F., Silva Milhiero, T., Gomes Neves, E., Corte-Real, R., Violari, A., Ramsagar, N., Liberty, A., Essack, Z., Akoojee, N., Fourie, Y., Erasmus, J., Cweya, A., Fry, S., Theunissen, M., Escosa García, L., Torrent, R., Torres Arauz, M., Guillén Martin, S., Boni, J., Mann, B., Saegesser, C., Ounchanum, P., Kaewmamueng, K., Srisuk, W., Kanjanavanit, S., Chutima, D., Chankun, T., Sudsaard, P., Kongsuk, K., Phunkhum, P., Kekitiinwa, A.R., Kirabira, A., Namuli, F., Kiyimba, L., Tikabibamu, J., Nabukeera Barung, N., Kityo, C.M., Kaudha, E., Ategeka, J., Mbabazi, R., Nabalamba, M., Nakalyango, A., Musiime, A., Mugarura, L., Katemba, C., Inyakuwal, C., Williams, E.D., Uyungrwoth, A., Raus, I., Mostovenko, O., Kenny, J., Ahmad, M., Nayagam, D., Ball, C., Hamlyn, E., Gilmour-White, S., Doshi, S., Fuller, E., Tupper, K., Irvine, E., Vaughn-Gordon, Y., Sibanda, N.

“…Integrase inhibitor (INSTI) with boosted darunavir (DRV/r), a regimen with a high-resistance barrier, avoiding NRTI toxicities, might be a switching option in…”
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Evaluation of certain ureas and nitrosoureas of 2,3-dihydro-1,4-benzothiazines against Sarcoma-180 solid tumors in vivo by Nyati, M K, Rajoria, C M, Gupta, R R, Dev, P K

“…Different derivatives of nitrosoureas were synthesized by a long sequence of reactions and were evaluated for their anticancer activities against female Swiss…”
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Early disease progression in a phase I study of bortezomib (B), cetuximab (C), and intensity-modulated radiation therapy (IMRT) for squamous cell carcinoma of the head and neck (SCCHN) by Van Waes, C., Duffy, A. G., Simone, N. L., Gibson, M. K., Arai, Y., Rudy, S. F., Cooley-Zgela, T., Nyati, M., Wright, J. J., Argiris, A.

“…Abstract only…”
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Differential tumor and normal mucosa biomarker modulation by epidermal growth factor receptor (EGFR) inhibition using erlotinib in oral cavity squamous cell carcinoma (OCSCC) by Tsien, C., Nyati, M., Chepeha, D., Worden, F., Helman, J., Bradford, C., Wolf, G., Lawrence, T., Eisbruch, A.

“…Abstract only 6077 Background: Targeted therapy may improve the therapeutic index in locally advanced head neck cancer if differential EGFR inhibition in…”
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Development of differential cytotoxic compounds containing nitrosourea and benzothiazine nucleus by Nyati, M K, Rai, D, Gupta, R R, Dev, P K

“…The in vivo activity of 4 new benzothiazinyl-nitrosourea compounds was investigated against Sarcoma-180 (S-180) and Ehrlich Ascitic Carcinoma (EAC) induced…”
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Longterm Antiretroviral Treatment Effects in a Multi-country Observational Cohort of Reproductive Age Women in Sub-Saharan Africa: The PEPFAR PROMOTE Study Findings by Taha, Taha E., Yende-Zuma, Nonhlanhla, Brummel, Sean S., Stranix-Chibanda, Lynda, Ogwang, Lillian Wambuzi, Dadabhai, Sufia, Chinula, Lameck, Nyati, Mandisa M., Hanley, Sherika, Makanani, Bonus, Chipato, Tsungai, Atuhaire, Patience, Aizire, Jim, Fowler, Mary Glenn

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Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma by CHUN, Patrick Y, FENG, Felix Y, SCHEURER, Ashley M, DAVIS, Mary A, LAWRENCE, Theodore S, NYATI, Mukesh K

“…Although the combination of gemcitabine and radiation produces a high frequency of complete responses in the treatment of locally advanced head and neck…”
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Radiosensitization by Pan ErbB Inhibitor CI-1033 in Vitro and in Vivo by NYATI, Mukesh K, MAHESHWARI, Divya, HANASOGE, Sheela, SREEKUMAR, Arun, RYNKIEWICZ, Susan D, CHINNAIYAN, Arul M, LEOPOLD, Wilbur R, ETHIER, Stephen P, LAWRENCE, Theodore S

“…Purpose: Overexpression of the ErbB family of receptor tyrosine kinases has been associated with uncontrolled growth of many tumor types and, therefore,…”
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