Search Results - "Nyarko, Prince B"
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Phenotypic characterization of Ghanaian P. falciparum clinical isolates reveals a homogenous parasite population
Published in Frontiers in immunology (23-09-2022)“…Erythrocyte invasion by P. falciparum involves functionally overlapping interactions between the parasite's ligands and the erythrocyte surface receptors…”
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Blood donor variability is a modulatory factor for P. falciparum invasion phenotyping assays
Published in Scientific reports (29-03-2021)“…Human erythrocytes are indispensable for Plasmodium falciparum development. Unlike other eukaryotic cells, there is no existing erythroid cell line capable of…”
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Comparative analysis of asexual and sexual stage Plasmodium falciparum development in different red blood cell types
Published in Malaria journal (05-06-2020)“…Red blood cell (RBC) polymorphisms are suggested to influence the course of Plasmodium falciparum malaria. Whereas some variants have been found to be…”
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Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) Is Apically Localized in Free Merozoites and Antibodies Are Associated With Reduced Risk of Malaria
Published in Frontiers in immunology (07-04-2020)“…Understanding the functional role of proteins expressed by is an important step toward unlocking potential targets for the development of therapeutic or…”
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Understanding Host–Pathogen–Vector Interactions with Chronic Asymptomatic Malaria Infections
Published in Trends in parasitology (01-03-2021)“…The last malaria parasite standing will display effective adaptations to selective forces. While substantial progress has been made in reducing malaria…”
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Molecular Characterization and Immuno-Reactivity Patterns of a Novel Plasmodium falciparum Armadillo-Type Repeat Protein, PfATRP
Published in Frontiers in cellular and infection microbiology (20-03-2020)“…Nearly half of the genes in the genome have not yet been functionally investigated. We used homology-based structural modeling to identify multiple copies of…”
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Antimalarial activity of Malaria Box Compounds against Plasmodium falciparum clinical isolates
Published in International journal for parasitology -- drugs and drug resistance (01-12-2017)“…Malaria remains a major cause of childhood deaths in resource-limited settings. In the absence of an effective vaccine, drugs and other interventions have…”
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SMIM1 at a glance; discovery, genetic basis, recent progress and perspectives
Published in Parasite epidemiology and control (01-05-2019)“…Recent elucidation of the genetic basis of the Vel blood group system has offered the field of blood transfusion medicine an additional consideration in…”
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Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level
Published in Scientific reports (14-01-2020)“…The central role that erythrocyte invasion plays in Plasmodium falciparum survival and reproduction makes this process an attractive target for therapeutic or…”
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Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture
Published in Scientific reports (10-04-2018)“…The extensive redundancy in the use of invasion ligands by Plasmodium falciparum , and its unique ability to switch between invasion pathways have hampered…”
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Functional Characterization of Plasmodium falciparum Surface-Related Antigen as a Potential Blood-Stage Vaccine Target
Published in The Journal of infectious diseases (24-07-2018)“…Plasmodium falciparum erythrocyte invasion is a multistep process that involves a spectrum of interactions that are not well characterized. We have…”
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Localization and function of a Plasmodium falciparum protein (PF3D7_1459400) during erythrocyte invasion
Published in Experimental biology and medicine (Maywood, N.J.) (01-01-2021)“…Nearly 60% of Plasmodium falciparum proteins are still uncharacterized and their functions are unknown. In this report, we carried out the functional…”
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Analysis of Plasmodium falciparum Rh2b deletion polymorphism across different transmission areas
Published in Scientific reports (30-01-2020)“…Despite significant progress in controlling malaria, the disease remains a global health burden. The intricate interactions the parasite Plasmodium falciparum…”
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