Search Results - "Nyaga, Martin"

Poultry gut health – microbiome functions, environmental impacts, microbiome engineering and advancements in characterization technologies by Aruwa, Christiana Eleojo, Pillay, Charlene, Nyaga, Martin M., Sabiu, Saheed

“…Abstract The gastrointestinal tract (GIT) health impacts animal productivity. The poultry microbiome has functions which range from protection against…”
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A metagenomic investigation of the faecal RNA virome structure of asymptomatic chickens obtained from a commercial farm in Durban, KwaZulu-Natal province, South Africa by Nwokorogu, Vivian C, Pillai, Santhosh, San, James E, Pillay, Charlene, Nyaga, Martin M, Sabiu, Saheed

“…Virome studies on birds, including chickens are relatively scarce, particularly from the African continent. Despite the continuous evolution of RNA viruses and…”
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Cheminformatics bioprospection of selected medicinal plants metabolites against trypsin cleaved VP4 (spike protein) of rotavirus A by Lanrewaju, Adedayo Ayodeji, Enitan-Folami, Abimbola Motunrayo, Nyaga, Martin M., Sabiu, Saheed, Swalaha, Feroz Mahomed

“…Rotaviruses have continued to be the primary cause of acute dehydrating diarrhoea in children under five years of age despite the global introduction of four…”
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Metabolites profiling and cheminformatics bioprospection of selected medicinal plants against the main protease and RNA-dependent RNA polymerase of SARS-CoV-2 by Lanrewaju, Adedayo Ayodeji, Enitan-Folami, Abimbola Motunrayo, Nyaga, Martin M., Sabiu, Saheed, Swalaha, Feroz Mahomed

“…Despite the existence of some vaccines, SARS-CoV-2 (S-2) infections persist for various reasons relating to vaccine reluctance, rapid mutation rate, and an…”
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Metagenomics characterization of respiratory viral RNA pathogens in children under five years with severe acute respiratory infection in the Free State, South Africa by Ogunbayo, Ayodeji E., Mogotsi, Milton T., Sondlane, Hlengiwe, Sabiu, Saheed, Nyaga, Martin M.

“…Prompt detection of viral respiratory pathogens is crucial in managing respiratory infection including severe acute respiratory infection (SARI). Metagenomics…”
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Pathogen Profile of Children Hospitalised with Severe Acute Respiratory Infections during COVID-19 Pandemic in the Free State Province, South Africa by Ogunbayo, Ayodeji E., Mogotsi, Milton T., Sondlane, Hlengiwe, Nkwadipo, Kelebogile R., Sabiu, Saheed, Nyaga, Martin M.

“…Severe acute respiratory infections (SARI) contribute to mortality in children ≤5 years. Their microbiological aetiologies are often unknown and may be…”
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SARS-CoV-2-positive patients display considerable differences in proteome diversity in urine, nasopharyngeal, gargle solution and bronchoalveolar lavage fluid samples by Okendo, Javan, Musanabaganwa, Clarisse, Mwangi, Peter, Nyaga, Martin, Onywera, Harris

“…Proteome profile changes post-severe acute respiratory syndrome coronavirus 2 (post-SARS-CoV-2) infection in different body sites of humans remains an active…”
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Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa by Sondlane, Hlengiwe, Ogunbayo, Ayodeji, Donato, Celeste, Mogotsi, Milton, Esona, Mathew, Hallbauer, Ute, Bester, Phillip, Goedhals, Dominique, Nyaga, Martin

“…•The COVID-19 pandemic caused significant disruptions to the prevalence and spread of respiratory syncytial virus (RSV) and other respiratory viral infections…”
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Corrigendum to “Whole genome molecular analysis of respiratory syncytial virus pre and during the COVID-19 pandemic in Free State province, South Africa” [Virus Research, Volume 347, September 2024, 199421] by Sondlane, Hlengiwe, Ogunbayo, Ayodeji, Donato, Celeste, Mogotsi, Milton, Esona, Mathew, Hallbauer, Ute, Bester, Phillip, Goedhals, Dominique, Nyaga, Martin

“…Respiratory syncytial virus (RSV) is the most predominant viral pathogen worldwide in children with lower respiratory tract infections. The coronavirus disease…”
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Genomic insights into the 2022–2023Vibrio cholerae outbreak in Malawi by Chaguza, Chrispin, Chibwe, Innocent, Chaima, David, Musicha, Patrick, Ndeketa, Latif, Kasambara, Watipaso, Mhango, Chimwemwe, Mseka, Upendo L., Bitilinyu-Bangoh, Joseph, Mvula, Bernard, Kipandula, Wakisa, Bonongwe, Patrick, Munthali, Richard J., Ngwira, Selemani, Mwendera, Chikondi A., Kalizang’oma, Akuzike, Jambo, Kondwani C., Kambalame, Dzinkambani, Kamng’ona, Arox W., Steele, A. Duncan, Chauma-Mwale, Annie, Hungerford, Daniel, Kagoli, Matthew, Nyaga, Martin M., Dube, Queen, French, Neil, Msefula, Chisomo L., Cunliffe, Nigel A., Jere, Khuzwayo C.

“…Malawi experienced its deadliest Vibrio cholerae ( Vc ) outbreak following devastating cyclones, with >58,000 cases and >1700 deaths reported between March…”
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Report of the 1st African Enteric Viruses Genome Initiative (AEVGI) Data and Bioinformatics Workshop on whole-genome analysis of some African rotavirus strains held in Bloemfontein, South Africa by Nyaga, Martin M., Sabiu, Saheed, Ndze, Valantine N., Dennis, Francis E., Jere, Khuzwayo C.

“…The University of the Free State - Next Generation Sequencing (NGS) Unit, Bloemfontein, South Africa, hosted a data and bioinformatics workshop from 19 to 22…”
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Genetic characterization of G12P[6] and G12P[8] rotavirus strains collected in six African countries between 2010 and 2014 by Rakau, Kebareng G, Nyaga, Martin M, Gededzha, Maemu P, Mwenda, Jason M, Mphahlele, M Jeffrey, Seheri, L Mapaseka, Steele, A Duncan

“…G12 rotaviruses were first observed in sub-Saharan Africa in 2004 and since then have continued to emerge and spread across the continent and are reported as a…”
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Rotavirus Genotypes in Hospitalized Children With Acute Gastroenteritis Before and After Rotavirus Vaccine Introduction in Blantyre, Malawi, 1997–2019 by Mhango, Chimwemwe, Mandolo, Jonathan J, Chinyama, End, Wachepa, Richard, Kanjerwa, Oscar, Malamba-Banda, Chikondi, Matambo, Prisca B, Barnes, Kayla G, Chaguza, Chrispin, Shawa, Isaac T, Nyaga, Martin M, Hungerford, Daniel, Parashar, Umesh D, Pitzer, Virginia E, Kamng’ona, Arox W, Iturriza-Gomara, Miren, Cunliffe, Nigel A, Jere, Khuzwayo C

“…Abstract Background Rotavirus vaccine (Rotarix [RV1]) has reduced diarrhea-associated hospitalizations and deaths in Malawi. We examined the trends in…”
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Whole Genome Analysis of Human Rotaviruses Reveals Single Gene Reassortant Rotavirus Strains in Zambia by Maringa, Wairimu M, Simwaka, Julia, Mwangi, Peter N, Mpabalwani, Evans M, Mwenda, Jason M, Mphahlele, M Jeffrey, Seheri, Mapaseka L, Nyaga, Martin M

“…Rotarix vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole…”
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Metagenomic Analysis of Respiratory RNA Virome of Children with and without Severe Acute Respiratory Infection from the Free State, South Africa during COVID-19 Pandemic Reveals Higher Diversity and Abundance in Summer Compared with Winter Period by Ogunbayo, Ayodeji E, Mogotsi, Milton T, Sondlane, Hlengiwe, Nkwadipo, Kelebogile R, Sabiu, Saheed, Nyaga, Martin M

“…Viral respiratory infections contribute to significant morbidity and mortality in children. Currently, there are limited reports on the composition and…”
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Whole-genome characterization of G12 rotavirus strains detected in Mozambique reveals a co-infection with a GXP[14] strain of possible animal origin by Strydom, Amy, Motanyane, Lithabiso, Nyaga, Martin M, João, Eva Dora, Cuamba, Assa, Mandomando, Inácio, Cassocera, Marta, de Deus, Nilsa, O'Neill, Hester

“…A high prevalence of G12 rotavirus strains has previously been reported in southern Mozambique. In this study, the full genomes of five Mozambican G12 strains…”
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Update of Rotavirus Strains Circulating in Africa From 2007 Through 2011 by Seheri, Mapaseka, Nemarude, Leah, Peenze, Ina, Netshifhefhe, Lufuno, Nyaga, Martin M, Ngobeni, Harry G, Maphalala, Gugu, Maake, Lorens L, Steele, A Duncan, Mwenda, Jason M, Mphahlele, Jeffrey M

“…BACKGROUND:The African Rotavirus Surveillance Network has been detecting and documenting rotavirus genotypes in the subcontinent since 1998, largely based on…”
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Metagenomic Analysis of the Enteric RNA Virome of Infants from the Oukasie Clinic, North West Province, South Africa, Reveals Diverse Eukaryotic Viruses by Mogotsi, Milton T, Mwangi, Peter N, Bester, Phillip A, Mphahlele, M Jeffrey, Seheri, Mapaseka L, O'Neill, Hester G, Nyaga, Martin M

“…Establishing a diverse gut microbiota after birth is essential for preventing illnesses later in life. However, little knowledge exists about the total viral…”
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Whole genome analyses of DS-1-like Rotavirus A strains detected in children with acute diarrhoea in southern Mozambique suggest several reassortment events by Strydom, Amy, João, Eva Dora, Motanyane, Lithabiso, Nyaga, Martin M., Christiaan Potgieter, A., Cuamba, Assa, Mandomando, Inacio, Cassocera, Marta, de Deus, Nilsa, O'Neill, Hester G.

“…We report the first whole genome constellations of Mozambican rotavirus A strains detected between 2012 and 2013 in the Mavalane General Hospital in Maputo…”
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Genomic Analysis of Rwandan G9P[8] Rotavirus Strains Pre- and Post-RotaTeq ® Vaccine Reveals Significant Distinct Sub-Clustering in a Post-Vaccination Cohort by Potgieter, Robyn-Lee, Mwangi, Peter N, Mogotsi, Milton T, Uwimana, Jeannine, Mutesa, Leon, Muganga, Narcisse, Murenzi, Didier, Tusiyenge, Lisine, Seheri, Mapaseka L, Steele, A Duncan, Mwenda, Jason M, Nyaga, Martin M

“…Although the introduction of rotavirus vaccines has substantially contributed to the reduction in rotavirus morbidity and mortality, concerns persist about the…”
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