Search Results - "Ny, Tor"

The plasminogen receptor, Plg-RKT, plays a role in inflammation and fibrinolysis during cutaneous wound healing in mice by Ny, Lina, Parmer, Robert J., Shen, Yue, Holmberg, Sandra, Baik, Nagyung, Bäckman, Assar, Broden, Jessica, Wilczynska, Malgorzata, Ny, Tor, Miles, Lindsey A.

“…Wound healing is a complex physiologic process that proceeds in overlapping, sequential steps. Plasminogen promotes fibrinolysis and potentiates the…”
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Plasminogen Receptors and Fibrinolysis by Miles, Lindsey A, Ny, Lina, Wilczynska, Malgorzata, Shen, Yue, Ny, Tor, Parmer, Robert J

“…The ability of cells to promote plasminogen activation on their surfaces is now well recognized, and several distinct cell surface proteins have been…”
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Beneficial and detrimental effects of plasmin(ogen) during infection and sepsis in mice by Guo, Yongzhi, Li, Jinan, Hagström, Elin, Ny, Tor

“…Plasmin has been proposed to be an important mediator during inflammation/infection. In this study, by using mice lacking genes for plasminogen, tissue-type…”
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Plasminogen is a master regulator and a potential drug candidate for the healing of radiation wounds by Fallah, Mahsa, Viklund, Emil, Bäckman, Assar, Brodén, Jessica, Lundskog, Bertil, Johansson, Michael, Blomquist, Michael, Wilczynska, Malgorzata, Ny, Tor

“…Around 95% of cancer patients undergoing radiotherapy experience cutaneous side effects, and some develop radiation wounds or fibrosis. Currently, there is no…”
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Mice deficient in urokinase-type plasminogen activator have delayed healing of tympanic membrane perforations by Shen, Yue, Guo, Yongzhi, Du, Chun, Wilczynska, Malgorzata, Hellström, Sten, Ny, Tor

“…Mice deficient in plasminogen, the precursor of plasmin, show completely arrested healing of tympanic membrane (TM) perforations, indicating that plasmin plays…”
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Plasmin/plasminogen is essential for the healing of tympanic membrane perforations by Li, Jinan, Eriksson, Per-Olof, Hansson, Annika, Hellström, Sten, Ny, Tor

“…Plasminogen has been proposed to play an important role in different tissue remodeling processes such as wound healing and tissue regeneration after injuries…”
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Residues Determining the Binding Specificity of Uncompetitive Inhibitors to Tissue‐Nonspecific Alkaline Phosphatase by Kozlenkov, Alexey, Le Du, Marie Helene, Cuniasse, Philippe, Ny, Tor, Hoylaerts, Marc F, Millán, José Luis

“…Recent data have pointed to TNALP as a therapeutic target for soft‐tissue ossification abnormalities. Here, we used mutagenesis, kinetic analysis, and computer…”
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The Plasminogen Activator/Plasmin System Is Essential for Development of the Joint Inflammatory Phase of Collagen Type II-Induced Arthritis by Li, Jinan, Ny, Annelii, Leonardsson, Göran, Nandakumar, Kutty Selva, Holmdahl, Rikard, Ny, Tor

“…The plasminogen activator (PA) system has been proposed to have important roles in rheumatoid arthritis. Here we have used the autoimmune collagen type II…”
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A reply to the commentary on ”Animal models of chronic tympanic membrane perforation: in response to plasminogen initiates and potentiates the healing of acute and chronic tympanic membrane perforations in mice” by Wang AY, Shen Y, Wang JT, Eikelboom RH and Dilley RJ; Clin Translat Med, 2014; 3:5 by Hellström, Sten, Shen, Yue, Ny, Tor

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Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling by Cheng, Fang, Shen, Yue, Mohanasundaram, Ponnuswamy, Lindström, Michelle, Ivaska, Johanna, Ny, Tor, Eriksson, John E.

“…Vimentin has been shown to be involved in wound healing, but its functional contribution to this process is poorly understood. Here we describe a previously…”
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The structure of a serpin–protease complex revealed by intramolecular distance measurements using donor–donor energy migration and mapping of interaction sites by Fa, Ming, Bergström, Fredrik, Hägglöf, Peter, Wilczynska, Malgorzata, Johansson, Lennart B-Å, Ny, Tor

“…Background: The inhibitors that belong to the serpin family are widely distributed regulatory molecules that include most protease inhibitors found in blood…”
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The Use of Site-Directed Fluorophore Labeling and Donor-Donor Energy Migration to Investigate Solution Structure and Dynamics in Proteins by Bergström, Fredrik, Hägglöf, Peter, Karolin, Jan, Ny, Tor, Lennart B.-Å. Johansson

“…The use of molecular genetics for introducing fluorescent molecules enables the use of donor-donor energy migration to determine intramolecular distances in a…”
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Intracellular Polymerization of the Serpin Plasminogen Activator Inhibitor Type 2 by Mikus, P, Ny, T

“…Plasminogen activator inhibitor type 2 (PAI-2) is synthesized in two molecular forms: an intracellular, nonglycosylated form and an extracellular, glycosylated…”
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Fluorescence and Absorption Spectroscopic Properties of Dipyrrometheneboron Difluoride (BODIPY) Derivatives in Liquids, Lipid Membranes, and Proteins by Karolin, Jan, Johansson, Lennart B.-A, Strandberg, Leif, Ny, Tor

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A Putative Stimulatory Role of Progesterone Acting via Progesterone Receptors in the Steroidogenic Cells of the Human Corpus Luteum by OTTANDER, U, HOSOKAWA, K, KUI LIU, BERGH, A, NY, T, OLOFSSON, J. I

“…To further explore the proposed auto-regulatory role of progesterone action in the human corpus luteum (CL), the expression and functional roles of…”
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Plasminogen is a critical regulator of cutaneous wound healing by Sulniute, Rima, Shen, Yue, Guo, Yong-Zhi, Fallah, Mahsa, Ahlskog, Nina, Ny, Lina, Rakhimova, Olena, Broden, Jessica, Boija, Hege, Moghaddam, Aliyeh, Li, Jinan, Wilczynska, Malgorzata, Ny, Tor

“…Wound healing is a complicated biological process that consist of partially overlapping inflammatory, proliferation and tissue remodelling phases. A successful…”
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Disturbed Laminar Blood Flow Causes Impaired Fibrinolysis and Endothelial Fibrin Deposition In Vivo by Glise, Lars, Larsson, Pia, Jern, Sverker, Borén, Jan, Levin, Malin, Ny, Tor, Fogelstrand, Per, Bergh, Niklas

“…Endothelial expression of tissue-type plasminogen activator (t-PA) is crucial for maintaining an adequate endogenous fibrinolysis. It is unknown how…”
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Plasminogen is a key proinflammatory regulator that accelerates the healing of acute and diabetic wounds by Shen, Yue, Guo, Yongzhi, Mikus, Peter, Sulniute, Rima, Wilczynska, Malgorzata, Ny, Tor, Li, Jinan

“…Despite decades of research on wound healing, effective biologic agents for the treatment of chronic wounds, especially diabetic wounds, are still lacking. In…”
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Expression of gonadotropin-releasing hormone and prothymosin-alpha messenger ribonucleic acid in the ovary by Oikawa, M, Dargan, C, Ny, T, Hsueh, A J

“…GnRH exerts paradoxical effects on ovarian cells through specific receptors. Based on observed direct effects of GnRH and its antagonists on ovarian functions,…”
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The Species‐Specific Differences in the cAMP Regulation of the Tissue‐Type Plasminogen Activator Gene between Rat, Mouse and Human is Caused by a One‐Nucleotide Substitution in the cAMP‐Responsive Element of the Promoters by Holmberg, Monica, Leonardsson, Göran, Tor, NY

“…In rat ovarian cells tissue‐type plasminogen activator (tPA) is induced by gonadotropins, by a cAMP‐dependent pathway and the induction correlates with the…”
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