Search Results - "Ny, L"

BRAF mutational status as a prognostic marker for survival in malignant melanoma: a systematic review and meta-analysis by Ny, L, Hernberg, M, Nyakas, M, Koivunen, J, Oddershede, L, Yoon, M, Wang, X, Guyot, P, Geisler, J

“…The analysis of the BRAF mutational status has been established as a standard procedure during diagnosis of advanced malignant melanoma due to the fact that…”
Get more information

Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models by Ny, L., Rizzo, L.Y., Belgrano, V., Karlsson, J., Jespersen, H., Carstam, L., Bagge, R.O., Nilsson, L.M., Nilsson, J.A.

“…The mouse strains usually used to generate patient-derived xenografts (PDXs) are immunocompromised, rendering them unsuitable for immunotherapy studies. Here…”
Get full text

Randomised clinical trial: the efficacy of a transient receptor potential vanilloid 1 antagonist AZD1386 in human oesophageal pain by Krarup, A. L., Ny, L., Åstrand, M., Bajor, A., Hvid‐Jensen, F., Hansen, M. B., Simrén, M., Funch‐Jensen, P., Drewes, A. M.

“…Aliment Pharmacol Ther 2011; 33: 1113–1122 Summary Background  Many patients with gastro‐oesophageal reflux disease (GERD) are hypersensitive to heat and acid…”
Get full text

Validation of a clinicopathological and gene expression profile model to identify patients with cutaneous melanoma where sentinel lymph node biopsy is unnecessary by Johansson, I., Tempel, D., Dwarkasing, J.T., Rentroia-Pacheco, B., Mattsson, J., Ny, L., Olofsson Bagge, R.

“…In patients with cutaneous melanoma, sentinel lymph node biopsy (SLNB) serves as an important technique to asses disease stage and to guide adjuvant systemic…”
Get full text

Hyperbaric oxygen treatment reverses radiation induced pro-fibrotic and oxidative stress responses in a rat model by Oscarsson, N., Ny, L., Mölne, J., Lind, F., Ricksten, S.-E., Seeman-Lodding, H., Giglio, D.

“…Radiotherapy is effective in the treatment of tumors in the pelvic area but is associated with side effects such as cystitis and proctitis. Hyperbaric Oxygen…”
Get full text

Corrigendum to ‘Supporting clinical decision making in advanced melanoma by preclinical testing in personalized immune-humanized xenograft mouse models’: Annals of Oncology Volume 31, Issue 2, Pages 266–273 by Ny, L., Rizzo, L.Y., Belgrano, V., Karlsson, J., Jespersen, H., Carstam, L., Olofsson Bagge, R., Nilsson, L.M., Nilsson, J.A.

Get full text

Understanding quality of life issues in patients with advanced melanoma: Phase 1 and 2 in the development of the EORTC advanced melanoma module by Egeler, M.D., van Leeuwen, M., Lai-Kwon, J., Eriksson, H., Bartula, I., Elashwah, S., Fox, L., Van Hemelrijck, M., Jefford, M., Lijnsvelt, J., Bagge, A.-S. Lindqvist, Morag, O., Ny, L., Bagge, R. Olofsson, Rogiers, A., Saw, R.P.M., Serpentini, S., Iannopollo, L., Thompson, J., Stiller, H. Tufvesson, Vanlaer, N., van Akkooi, A.C.J., van de Poll-Franse, L.V.

“…We aimed to develop a European Organization for Research and Treatment of Cancer (EORTC) Quality of Life (QoL) module tailored for patients with advanced…”
Get full text

Bacterial flora of the human oral cavity, and the upper and lower esophagus by Norder Grusell, E., Dahlén, G., Ruth, M., Ny, L., Quiding-Järbrink, M., Bergquist, H., Bove, M.

“…Summary This reference study aims to survey the bacterial flora of the healthy lower human esophagus and to compare it with that of the upper esophagus and…”
Get full text

Adjuvant therapies for malignant melanoma by Olofsson Bagge, R., Ny, L.

“…More promise from targeted therapy…”
Get full text

Phase II multicenter open label study of pembrolizumab and entinostat in adult patients with metastatic uveal melanoma (PEMDAC study) by Jespersen, H., Olofsson Bagge, R., Ullenhag, G., Carneiro, A., Helgadottir, H., Ljuslinder, I., Levin, M., All-Eriksson, C., Andersson, B., Stierner, U., Nilsson, L.M., Nilsson, J.A., Ny, L.

Get full text

The efficacy of immune checkpoint blockade for melanoma in-transit with or without nodal metastases: A multicenter cohort study by Olofsson Bagge, Roger, Holmberg, Carl Jacob, Hieken, Tina J., Zager, Jonathan S., Long, Georgina V., Van Akkooi, Alexander Christopher Jonathan, Karakousis, Giorgos C, Pallan, Lalit, Vetto, John T., Gyorki, David E., Ascierto, Paolo Antonio, Dummer, Reinhard, Hui, Jane Yuet Ching, Schachter, Jacob, Helgadottir, Hildur, Kroon, Hidde, Rothermel, Luke Daniel, Carlino, Matteo S., Broman, Kristy Kummerow, Ny, Lars

“…9569 Background: Guidelines addressing melanoma in-transit metastasis (ITM) recommend immune checkpoint inhibitors (ICI) as a first-line treatment option,…”
Get full text

Downregulation of toll-like receptor 4 and IL-6 following irradiation of the rat urinary bladder by Giglio, D, Wasén, C, Mölne, J, Suchy, D, Swanpalmer, J, Jabonero Valbuena, J, Tobin, G, Ny, L

“…Summary The pathophysiology behind radiation cystitis is poorly understood. Here we investigated whether bladder irradiation affects the immune system of the…”
Get full text

A phase Ib randomized multicenter trial of isolated hepatic perfusion in combination with ipilimumab and nivolumab for uveal melanoma metastases (SCANDIUM II trial) by Olofsson Bagge, R., Nelson, A., Shafazand, A., Cahlin, C., Carneiro, A., Helgadottir, H., Levin, M., Rizell, M., Ullenhag, G., Wirén, S., Lindnér, P., Nilsson, J.A., Ny, L.

“…Uveal melanoma (UM) is a rare malignancy where 50% of patients develop metastatic disease primarily affecting the liver. Approximately 40% of patients with…”
Get full text

The effects of a novel metabotropic glutamate receptor 5 antagonist (AZD2066) on transient lower oesophageal sphincter relaxations and reflux episodes in healthy volunteers by Rohof, W. O., Lei, A., Hirsch, D. P., Ny, L., Astrand, M., Hansen, M. B., Boeckxstaens, G. E.

“…Summary Background Selective metabotropic glutamate receptor 5 (mGluR5) antagonists inhibit transient lower oesophageal sphincter relaxations (TLESRs) in…”
Get full text

Pitfalls using metalloporphyrins in carbon monoxide research by Grundemar, L., Ny, L.

“…The proposal that endogenously produced carbon monoxide (CO) may act as a biological messenger has remained controversial. Carbon monoxide is generated by haem…”
Get full text

Nitric oxide and endothelin-1 release after one-lung ventilation during thoracoabdominal esophagectomy by Lund, M., Ny, L., Malmström, R. E., Lundberg, J. O., Öst, Å., Björnstedt, M., Lundell, L., Tsai, J. A.

“…SUMMARY One‐lung ventilation (OLV) is applied during esophagectomy to improve exposure during the thoracic part of the operation. Collapse of lung tissue,…”
Get full text

Nitric oxide and endothelin-1 release after one-lung ventilation during thoracoabdominal oesophagectomy: 5AP1–4 by Lund, M, Ny, L, Malmström, R, Lundell, L, Tsai, J

Get full text

Reporter bacteriophage T7 NLC utilizes a novel NanoLuc::CBM fusion for the ultrasensitive detection of Escherichia coli in water by Hinkley, T C, Garing, S, Singh, S, Le Ny, A-L M, Nichols, K P, Peters, J E, Talbert, J N, Nugen, S R

“…Rapid detection of bacteria responsible for foodborne diseases is a growing necessity for public health. Reporter bacteriophages (phages) are robust…”
Get more information

Wetting, disintegration and dissolution of agglomerated water soluble powders by Forny, L., Marabi, A., Palzer, S.

“…Agglomeration technologies are commonly used by the food industry to optimize several properties such as density and flowability and also to shorten the…”
Get full text

The PEMDAC phase 2 study of pembrolizumab and entinostat in patients with metastatic uveal melanoma by Ny, Lars, Jespersen, Henrik, Karlsson, Joakim, Alsén, Samuel, Filges, Stefan, All-Eriksson, Charlotta, Andersson, Bengt, Carneiro, Ana, Helgadottir, Hildur, Levin, Max, Ljuslinder, Ingrid, Olofsson Bagge, Roger, Sah, Vasu R., Stierner, Ulrika, Ståhlberg, Anders, Ullenhag, Gustav, Nilsson, Lisa M., Nilsson, Jonas A.

“…Preclinical studies have suggested that epigenetic therapy could enhance immunogenicity of cancer cells. We report the results of the PEMDAC phase 2 clinical…”
Get full text