Search Results - "Nwoka, Chiso"

Visualization of Dynamics of Single Endogenous mRNA Labeled in Live Mouse by Park, Hye Yoon, Lim, Hyungsik, Yoon, Young J., Follenzi, Antonia, Nwokafor, Chiso, Lopez-Jones, Melissa, Meng, Xiuhua, Singer, Robert H.

“…The transcription and transport of messenger RNA (mRNA) are critical steps in regulating the spatial and temporal components of gene expression, but it has not…”
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Preclinical findings on the potential of intranasal neuropeptide Y for treating hyperarousal features of PTSD by Nwokafor, Chiso, Serova, Lidia I., Sabban, Esther L.

“…Acoustic startle response (ASR) assesses hyperarousal, a core symptom of posttraumatic stress disorder (PTSD). Intranasal neuropeptide Y (NPY) administration…”
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Tagged actin mRNA dysregulation in IGF2BP1[Formula: see text] mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwokafor, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
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Tagged actin mRNA dysregulation in IGF2BP1Formula: see text mice by Núñez, Leti, Buxbaum, Adina R, Katz, Zachary B, Lopez-Jones, Melissa, Nwoka, Chiso, Czaplinski, Kevin, Pan, Feng, Rosenberg, Jason, Monday, Hannah R, Singer, Robert H

“…Gene expression is tightly regulated by RNA-binding proteins (RBPs) to facilitate cell survival, differentiation, and migration. Previous reports have shown…”
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Transcriptome profiles associated with resilience and susceptibility to single prolonged stress in the locus coeruleus and nucleus accumbens in male sprague-dawley rats by Nahvi, Roxanna J., Tanelian, Arax, Nwokafor, Chiso, Godino, Arthur, Parise, Eric, Estill, Molly, Shen, Li, Nestler, Eric J., Sabban, Esther L.

“…Although most people are subjected to traumatic stress at least once in their lifetime, only a subset develop long-lasting, stress-triggered neuropsychiatric…”
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Imaging cell-type-specific dynamics of mRNAs in living mouse brain by Nwokafor, Chiso, Singer, Robert H., Lim, Hyungsik

“…•The brain is characterized by the diversity of cell types.•Variability (i.e., noise) in the synthesis and intracellular movement of mRNAs is thought to play a…”
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Activation of NPY receptor subtype 1 by [D-His26]NPY is sufficient to prevent development of anxiety and depressive like effects in the single prolonged stress rodent model of PTSD by Nwokafor, Chiso, Serova, Lidia I., Nahvi, Roxanna J., McCloskey, Jaclyn, Sabban, Esther L.

“…The neuropeptide Y (NPY) system plays an important role in mediating resilience to the harmful effect of stress in post-traumatic stress disorder (PTSD). It…”
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Intranasal Neuropeptide Y as a Potential Therapeutic for Depressive Behavior in the Rodent Single Prolonged Stress Model in Females by Nahvi, Roxanna J., Tanelian, Arax, Nwokafor, Chiso, Hollander, Callie M., Peacock, Lauren, Sabban, Esther L.

“…The susceptibility to stress-elicited disorders is markedly influenced by sex. Women are twice as likely as men to develop posttraumatic stress disorder…”
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Single prolonged stress PTSD model triggers progressive severity of anxiety, altered gene expression in locus coeruleus and hypothalamus and effected sensitivity to NPY by Serova, Lidia I., Nwokafor, Chiso, Van Bockstaele, Elisabeth J., Reyes, Beverly A.S., Lin, Xiaoping, Sabban, Esther L.

“…PTSD is heterogeneous disorder that can be long lasting and often has delayed onset following exposure to a traumatic event. Therefore, it is important to take…”
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Variable Response of Norepinephrine Transporter to Traumatic Stress and Relationship to Hyperarousal by Nwokafor, Chiso, Serova, Lidia I., Tanelian, Arax, Nahvi, Roxanna J., Sabban, Esther L.

“…The noradrenergic systems play a key role in stress triggered disorders such as post-traumatic stress disorder (PTSD). We hypothesized that traumatic stress…”
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Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in mice by Dunn, Amelia D, Robinson, Shivon A, Nwokafor, Chiso, Estill, Molly, Ferrante, Julia, Shen, Li, Lemchi, Crystal O, Creus-Muncunill, Jordi, Ramirez, Angie, Mengaziol, Juliet, Brynildsen, Julia K, Leggas, Mark, Horn, Jamie, Ehrlich, Michelle E, Blendy, Julie A

“…Infants exposed to opioids are at high risk of exhibiting Neonatal Opioid Withdrawal Syndrome (NOWS), a combination of somatic withdrawal symptoms including…”
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IMP1, an mRNA binding protein that reduces the metastatic potential of breast cancer in a mouse model by Nwokafor, Chiso U, Sellers, Rani S, Singer, Robert H

“…Cells that are able to localize β-actin mRNA efficiently have decreased metastatic potential. Invasive carcinoma cells derived from primary mammary tumors have…”
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Single Prolonged Stress as a Prospective Model for Posttraumatic Stress Disorder in Females by Nahvi, Roxanna J, Nwokafor, Chiso, Serova, Lidia I, Sabban, Esther L

“…Sex plays an important role in susceptibility to stress triggered disorders. Posttraumatic Stress disorder (PTSD), a debilitating psychiatric disorder…”
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Transgenic Expression of ZBP1 in Neurons Suppresses Cocaine-Associated Conditioning by Lapidus, Kyle A. B, Nwokafor, Chiso, Scott, Daniel, Baroni, Timothy E, Tenenbaum, Scott A, Hiroi, Noboru, Singer, Robert H, Czaplinski, Kevin

“…To directly address whether regulating mRNA localization can influence animal behavior, we created transgenic mice that conditionally express Zipcode Binding…”
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