Search Results - "Nwabueze, Okechukwu"
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1
Hypocholesterolemic Effects of Kenaf Seed Oil, Macroemulsion, and Nanoemulsion in High‐Cholesterol Diet Induced Rats
Published in Journal of food science (01-03-2018)“…This study aimed to evaluate the effect of kenaf seed oil (KSO), kenaf seed oil‐in‐water macroemulsion (KSOM), kenaf seed oil‐in‐water nanoemulsions (KSON),…”
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2
Improvement of gastroprotective and anti-ulcer effect of kenaf seed oil-in-water nanoemulsions in rats
Published in Food science and biotechnology (01-08-2018)“…Kenaf seed oil-in-water nanoemulsions (KSON) and kenaf seed oil-in-water macroemulsions were produced to access their gastroprotective effect against…”
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3
Induction of a single dose of streptozotocin (50 mg) in rat model causes insulin resistance with type 2 diabetes mellitus
Published in Fundamental & clinical pharmacology (01-08-2023)“…Streptozotocin (STZ) is a broad‐spectrum antibiotic that is toxic to the insulin‐producing beta cells of the pancreatic islets. STZ is currently used…”
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4
Analysis of Lipophilicity and Pharmacokinetic Parameters of Dipyridothiazine Dimers with Anticancer Potency
Published in Pharmaceutics (23-09-2024)“…Lipophilicity is an essential parameter of a compound that determines the solubility and pharmacokinetic properties that determine the transport of the drug to…”
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5
High-performance liquid chromatography identification of gastroprotective and antioxidant effects of purified fractions A-E from the stem of Coscinium fenestratum
Published in Pharmacognosy Magazine (01-04-2018)“…Objective: Coscinium fenestratum belongs to the family of Menispermaceae. It is a woody plant that originated from Indomalaya regions such as southern India,…”
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6
Eicosane, pentadecane and palmitic acid: The effects in in vitro wound healing studies
Published in Asian Pacific journal of tropical biomedicine (01-10-2018)“…Objective: To examine the wound healing properties of eicosane, pentadecane and palmitic acid by evaluating in term of anti-microbial, anti-inflammatory,…”
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7
Comparative Studies of Palmatine with Metformin and Glimepiride on the Modulation of Insulin Dependent Signaling Pathway In Vitro, In Vivo & Ex Vivo
Published in Pharmaceuticals (Basel, Switzerland) (25-10-2022)“…(1) Insulin resistance, a symptom of type 2 diabetes mellitus (T2DM), is caused by the inactivation of the insulin signaling pathway, which includes…”
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8
Spirulina supplementation improves bone structural strength and stiffness in streptozocin-induced diabetic rats
Published in Journal of Traditional and Complementary Medicine (01-05-2022)“…Spirulina (blue-green algae) contains a wide range of nutrients with medicinal properties which include b-carotene, chromium, and moderate amounts of vitamins…”
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9
Antioxidant and anti-advanced glycation end products formation properties of palmatine
Published in Journal of pharmacy & pharmacognosy research (01-05-2021)“…Context: Oxidative stress and formation of advanced glycation end products (AGEs), due to glycation of proteins, lipids and nucleic acids are characteristic in…”
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10
Is the consumption of energy drink beneficial or detrimental to health: a comprehensive review?
Published in Bulletin of the National Research Centre (04-06-2022)“…Background Energy drinks (EDs) are a type of beverage that mostly contains caffeine and other dietary supplements (if present) and does not contain any alcohol…”
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11
Polymorphisms in P53 and VEGFA genes in different subtypes of periorbital hyperpigmentation in a Malaysian Chinese population
Published in Australasian journal of dermatology (01-05-2019)“…Background/Objectives The unknown pathogenesis of periorbital hyperpigmentation makes its treatment difficult. Existing evidence links p53 and VEGFA genes with…”
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12
10H-3,6-Diazaphenothiazine induces G2/M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes
Published in Drug design, development and therapy (2017)“…The asymptomatic properties and high treatment resistance of ovarian cancer result in poor treatment outcomes and high mortality rates. Although the…”
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13
10 H -3,6-Diazaphenothiazine induces G 2 /M phase cell cycle arrest and caspase-dependent apoptosis and inhibits cell invasion of A2780 ovarian carcinoma cells through the regulation of NF-κB and (BIRC6-XIAP) complexes
Published in Drug design, development and therapy (01-10-2017)“…The asymptomatic properties and high treatment resistance of ovarian cancer result in poor treatment outcomes and high mortality rates. Although the…”
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14
In vivo antioxidant potentials of rambutan, mangosteen, and langsat peel extracts and effects on liver enzymes in experimental rats
Published in Food science and biotechnology (01-02-2015)“…Antioxidative potentials of peel extracts of rambutan ( Nephelium lappaceum ), mangosteen ( Garcinia mangostana ), and langsat ( Lansium domesticum ) in…”
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15
Effect of standardized extract of Cosinium fenestratum stem bark on liver and kidney function parameters in streptozotocin-induced diabetic rats
Published in Journal of acute disease (2013)“…To investigate the effects of standardized dichloromethane (DCM) extract of Cosinium fenestratum (C. fenestratum) stem bark on liver and kidney function…”
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16
Safety and Efficacy of Direct Oral Anticoagulants in Morbidly Obese Patients: A Meta-Analysis
Published in Blood (13-11-2019)“…Background: Direct oral anticoagulants (DOACS) were recently approved for anticoagulation in patients with atrial fibrillation for prevention of stroke and…”
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17
In vitro antioxidant, antiglycation, and MGO scavenging effects of Leonurus sibiricus water extract
Published in Asia-Pacific journal of molecular biology and biotechnology (2021)“…Recently, extensive research has been conducted to evaluate the inhibitory activity of different plant species on the advanced glycation end products (AGEs)…”
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18
Eicosane, pentadecane and palmitic acid: The effects inin vitro wound healing studies
Published in 亚太热带生物医学杂志(英文版) (2018)“…Objective:To examine the wound healing properties of eicosane, pentadecane and palmitic acid by evaluating in term of anti-microbial, anti-inflammatory,…”
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19
THE EVALUATION OF BONE PROTEOME OF PALM VITAMIN E‐SUPPLEMENTATION IN OVARIECTOMISED RATS
Published in The FASEB journal (01-04-2012)“…Abstract only…”
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20
EVALUATION OF ANTI-INFLAMMATORY, ANALGESIC, ANTIPYRETIC EFFECT OF EICOSANE, PENTADECANE, OCTACOSANE, AND HENEICOSANE
Published in Asian journal of pharmaceutical and clinical research (07-02-2020)“…Objective: Marantodes pumilum (MP) is a plant widely used in traditional medicine in the Southeast Asian region and been reported to possess anti-inflammatory,…”
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