Search Results - "Nuzzo, P. A."

Pharmacokinetics of Intranasal Crushed OxyContin and Intravenous Oxycodone in Nondependent Prescription Opioid Abusers by Lofwall, M. R., Moody, D. E., Fang, W. B., Nuzzo, P. A., Walsh, S. L.

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Abuse liability and reinforcing efficacy of oral tramadol in humans by Babalonis, Shanna, Lofwall, Michelle R, Nuzzo, Paul A, Siegel, Anthony J, Walsh, Sharon L

“…Abstract Background Tramadol, a monoaminergic reuptake inhibitor, is hepatically metabolized to an opioid agonist (M1). This atypical analgesic is generally…”
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Opioid withdrawal suppression efficacy of oral dronabinol in opioid dependent humans by Lofwall, Michelle R, Babalonis, Shanna, Nuzzo, Paul A, Elayi, Samy Claude, Walsh, Sharon L

“…Highlights • Dronabinol, a partial CB1 agonist, was evaluated among adults in opioid withdrawal. • Dronabinol 20 and 30 mg doses produced modest evidence of…”
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Safety of oral dronabinol during opioid withdrawal in humans by Jicha, Crystal J, Lofwall, Michelle R, Nuzzo, Paul A, Babalonis, Shanna, Elayi, Samy Claude, Walsh, Sharon L

“…Highlights • This study evaluated acute doses of oral dronabinol, a CB1 agonist, in adults during spontaneous opioid withdrawal. • Dronabinol 20 and 30 mg…”
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The relative abuse liability of oral oxycodone, hydrocodone and hydromorphone assessed in prescription opioid abusers by Walsh, Sharon L, Nuzzo, Paul A, Lofwall, Michelle R, Holtman, Joseph R

“…Abstract Abuse of prescription opioids has risen precipitously in the United States. Few controlled comparisons of the abuse liability of the most commonly…”
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The pharmacodynamic and pharmacokinetic profile of intranasal crushed buprenorphine and buprenorphine/naloxone tablets in opioid abusers by Middleton, Lisa S., Nuzzo, Paul A., Lofwall, Michelle R., Moody, David E., Walsh, Sharon L.

“…ABSTRACT Aims  Sublingual buprenorphine and buprenorphine/naloxone are efficacious opioid dependence pharmacotherapies, but there are reports of their…”
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Characterizing opioid withdrawal during double-blind buprenorphine detoxification by Dunn, Kelly E, Saulsgiver, Kathryn A, Miller, Mollie E, Nuzzo, Paul A, Sigmon, Stacey C

“…Highlights • Evaluation of withdrawal following 1, 2, or 4-week outpatient buprenorphine taper. • Withdrawal assessed daily using self-reports,…”
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Intravenous oxycodone, hydrocodone, and morphine in recreational opioid users: abuse potential and relative potencies by Stoops, William W., Hatton, Kevin W., Lofwall, Michelle R., Nuzzo, Paul A., Walsh, Sharon L.

“…Rationale Nonmedical use and abuse of prescription opioids is an increasing public health problem. Intravenous (IV) administration of opioid analgesics…”
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Intranasal buprenorphine alone and in combination with naloxone: Abuse liability and reinforcing efficacy in physically dependent opioid abusers by Walsh, Sharon L, Nuzzo, Paul A, Babalonis, Shanna, Casselton, Victoria, Lofwall, Michelle R

“…Highlights • Inpatient study examined persons dependent on short-acting opioids. • Intranasal (IN) buprenorphine/naloxone (BUP/NX) precipitated opioid…”
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Efficacy of extended-release tramadol for treatment of prescription opioid withdrawal: A two-phase randomized controlled trial by Lofwall, Michelle R, Babalonis, Shanna, Nuzzo, Paul A, Siegel, Anthony, Campbell, Charles, Walsh, Sharon L

“…Abstract Background Tramadol is an atypical analgesic with monoamine and modest mu opioid agonist activity. The purpose of this study was to evaluate: (1) the…”
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Effects of Short-Term Oxycodone Maintenance on Experimental Pain Responses in Physically Dependent Opioid Abusers by Coe, Marion A, Nuzzo, Paul A, Lofwall, Michelle R, Walsh, Sharon L

“…A common clinical problem with opioid analgesics is the loss of analgesic efficacy after repeated dosing; when this occurs, it is not clear what principles…”
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Pharmacodynamic profile of tramadol in humans: influence of naltrexone pretreatment by Stoops, William W., Lofwall, Michelle R., Nuzzo, Paul A., Craig, Lori B., Siegel, Anthony J., Walsh, Sharon L.

“…Rationale Tramadol is a prescription analgesic that activates mu opioid and monoamine receptor systems. Tramadol is thought to have limited abuse potential…”
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A novel oral oxycodone maintenance procedure for human laboratory studies by Coe, Marion A, Nuzzo, Paul A, Lofwall, Michelle R, Walsh, Sharon L

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Effects of extended release tramadol on cigarette smoking during opioid withdrawal by Lofwall, Michelle R, Babalonis, Shanna, Bennett, Luke, Nuzzo, Paul A, Walsh, Sharon L

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Methadone-Related Overdose Deaths in Rural Virginia: 1997 to 2003 by Wunsch, Martha J, Nuzzo, Paul A, Behonick, George, Massello, William, Walsh, Sharon L

“…AIM:Nonmedical use of prescription drugs and poisoning overdose deaths related to prescription drugs are increasing. This article presents an in-depth…”
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QT-interval effects of methadone, levomethadyl, and buprenorphine in a randomized trial by Wedam, Erich F, Bigelow, George E, Johnson, Rolley E, Nuzzo, Paul A, Haigney, Mark C P

“…Levomethadyl acetate, methadone hydrochloride, and buprenorphine hydrochloride are equally effective treatments for opioid dependence. Each blocks the human…”
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Efficacy of continuing medical education to reduce the risk of buprenorphine diversion by Lofwall, Michelle R., M.D, Wunsch, Martha J., M.D, Nuzzo, Paul A, Walsh, Sharon L., Ph.D

“…Abstract As office-based opioid dependence treatment (OBOT) has grown in the United States, postmarketing surveillance data reveal increased reports of…”
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