Search Results - "Nuzum, Edwin O"

An interagency collaboration to facilitate development of filovirus medical countermeasures by Kilgore, Nicole, Nuzum, Edwin O

“…The Filovirus Animal Non-Clinical Group (FANG) is a US interdepartmental and interagency group established to support and facilitate the advanced development…”
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Anthrax vaccine-induced antibodies provide cross-species prediction of survival to aerosol challenge by Fay, Michael P, Follmann, Dean A, Lynn, Freyja, Schiffer, Jarad M, Stark, Gregory V, Kohberger, Robert, Quinn, Conrad P, Nuzum, Edwin O

“…Because clinical trials to assess the efficacy of vaccines against anthrax are not ethical or feasible, licensure for new anthrax vaccines will likely involve…”
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8-Aminoquinolines Active against Blood Stage Plasmodium falciparum In Vitro Inhibit Hematin Polymerization by VENNERSTROM, J. L, NUZUM, E. O, MILLER, R. E, DORN, A, GERENA, L, DANDE, P. A, ELLIS, W. Y, RIDLEY, R. G, MILHOUS, W. K

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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In Vitro Antimalarial Activity of Chalcones and Their Derivatives by Li, Rongshi, Kenyon, George L, Cohen, Fred E, Chen, Xiaowu, Gong, Baoqing, Dominguez, Jose N, Davidson, Eugene, Kurzban, Gary, Miller, Robert E, Nuzum, Edwin O, Rosenthal, Philip J, McKerrow, James H

“…A series of chalcones and their derivatives have been synthesized and identified as novel potential antimalarials using both molecular modeling and in vitro…”
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WR 238605, chloroquine, and their combinations as blood schizonticides against a chloroquine-resistant strain of Plasmodium vivax in Aotus monkeys by Obaldia, 3rd, N, Rossan, R N, Cooper, R D, Kyle, D E, Nuzum, E O, Rieckmann, K H, Shanks, G D

“…The compound WR 238605 is a primaquine analog being developed by the U.S. Army as an antimalarial drug. Currently, there is no established treatment for…”
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Specific Ki-ras codon 61 mutations may determine the development of urethan-induced mouse lung adenomas or adenocarcinomas by Nuzum, E O, Malkinson, A M, Beer, D G

“…In A/J strain mice, the carcinogen urethan induces lung adenomas and adenocarcinomas that contain Ki-ras-activating mutations primarily in codon 61. These…”
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Aerosol transmission of Hantaan and related viruses to laboratory rats by Nuzum, E O, Rossi, C A, Stephenson, E H, LeDuc, J W

“…Hantaan, Seoul, and Puumala viruses were transmitted to 12-16-week-old female Wistar Rattus norvegicus by inhalation. The rodent infectious dose for each virus…”
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Structure-based design of parasitic protease inhibitors by Li, Rongshi, Chen, Xiaowu, Gong, Baoqing, Selzer, Paul M., Li, Zhe, Davidson, Eugene, Kurzban, Gary, Miller, Robert E., Nuzum, Edwin O., McKerrow, James H., Fletterick, Robert J., Gillmor, Sarah A., Craik, Charles S., Kuntz, Irwin D., Cohen, Fred E., Kenyon, George L.

“…To streamline the preclinical phase of pharmaceutical development, we have explored the utility of structural data on the molecular target and synergy between…”
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Ki-ras activation and expression in transformed mouse lung cell lines by Pan, Y H, Nuzum, E O, Hanson, L A, Beer, D G

“…The Ki-ras proto-oncogene is activated by specific point mutations and is the transforming gene often identified in rodent and human lung tumors. An in vitro…”
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Expression of the glucocorticoid receptor and K-ras genes in urethan-induced mouse lung tumors and transformed cell lines by Hanson, L A, Nuzum, E O, Jones, B C, Malkinson, A M, Beer, D G

“…Glucocorticoids influence cell proliferation and differentiation in the lung. We examined the expression of the glucocorticoid receptor (GR) gene in…”
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