Search Results - "Nuydens, R."

Therapeutic potential of VEGF and VEGF-derived peptide in peripheral neuropathies by Verheyen, A, Peeraer, E, Lambrechts, D, Poesen, K, Carmeliet, P, Shibuya, M, Pintelon, I, Timmermans, J.-P, Nuydens, R, Meert, T

“…Graphical abstract VEGF and VEGF-derived peptide protect against hyperglycemia-and paclitaxel-induced neuronal stress (A, B). VEGF also has therapeutic…”
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Mitochondrial abnormality in sensory, but not motor, axons in paclitaxel-evoked painful peripheral neuropathy in the rat by Xiao, W.H, Zheng, H, Zheng, F.Y, Nuydens, R, Meert, T.F, Bennett, G.J

“…Abstract The dose-limiting side effect of the anti-neoplastic agent, paclitaxel, is a chronic distal symmetrical peripheral neuropathy that produces sensory…”
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Evaluation of established human iPSC-derived neurons to model neurodegenerative diseases by Meneghello, G, Verheyen, A, Van Ingen, M, Kuijlaars, J, Tuefferd, M, Van Den Wyngaert, I, Nuydens, R

“…Highlights • Commercially available iCell®-derived neurons are primarily immature and GABAergic. • Conditioned medium improves the bursting frequency of iCell®…”
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Annexin V binding assay as a tool to measure apoptosis in differentiated neuronal cells by Schutte, B., Nuydens, R., Geerts, H., Ramaekers, F.

“…We describe a rapid and reliable method to quantitate the extent of apoptosis in neuronal cell cultures. Based on their annexin V-affinity, resulting from…”
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Bone cancer pain model in mice: evaluation of pain behavior, bone destruction and morphine sensitivity by Vermeirsch, Hilde, Nuydens, Rony M., Salmon, Philip L., Meert, Theo F.

“…The primary aim of the study was to correlate pain development during bone cancer growth with objectively obtained tumor-induced changes in bone morphology…”
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Coexpression of GSK-3β Corrects Phenotypic Aberrations of Dorsal Root Ganglion Cells, Cultured from Adult Transgenic Mice Overexpressing Human Protein tau by Nuydens, R., Van Den Kieboom, G., Nolten, C., Verhulst, C., Van Osta, P., Spittaels, K., Van den Haute, C., De Feyter, E., Geerts, H., Van Leuven, F.

“…Coexpression of constitutively active GSK-3β[S9A] rescued the axonal pathology induced by overexpression of human tau in transgenic mice (Spittaels et al.,…”
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In vitro effects of histamine and glutamate on the function of Aquaporin-4 in astrocytes: P 022 by de Vooght, P, Mertens, S, Houben, A, Nuydens, R, De Jongh, R, Meert, T

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A multiparametric assay for quantitative nerve regeneration evaluation by WEYN, B., VAN REMOORTERE, M., NUYDENS, R., MEERT, T., VAN DE WOUWER, G.

“…Summary We introduce an assay for the semi‐automated quantification of nerve regeneration by image analysis. Digital images of histological sections of…”
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Bcl-2 protects neuronal cells against taxol-induced apoptosis by inducing multi-nucleation by Nuydens, R, Dispersyn, G, Van Den Kieboom, G, de Jong, M, Connors, R, Ramaekers, F, Borgers, M, Geerts, H

“…Taxol-induced peripheral neuropathy is a commonly-occurring side-effect in the treatment of cancer patients with taxoteres or taxanes. Taxol is known to induce…”
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Taxol Induces the Assembly of Free Microtubules in Living Cells and Blocks the Organizing Capacity of the Centrosomes and Kinetochores by De Brabander, M., Geuens, G., Nuydens, R., Willebrords, R., De Mey, J.

“…Taxol, a potent promoter of microtubule polymerization in vitro, induces massive assembly of free microtubules in cultured cells as visualized by…”
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Nanovid tracking: a new automatic method for the study of mobility in living cells based on colloidal gold and video microscopy by Geerts, H., De Brabander, M., Nuydens, R., Geuens, S., Moeremans, M., De Mey, J., Hollenbeck, P.

“…We describe a new automatic technique for the study of intracellular mobility. It is based on the visualization of colloidal gold particles by video-enhanced…”
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Ultrastructural Colocalization of Tyrosinated and Detyrosinated α-Tubulin in Interphase and Mitotic Cells by Geuens, Gustaaf, Gundersen, Gregg G., Nuydens, Rony, Cornelissen, Frans, Bulinski, Jeannette Chloe, DeBrabander, Marc

“…Immunofluorescence with specific peptide antibodies has previously established that tyrosinated (Tyr) and detyrosinated (Glu) tubulin, the two species…”
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Altered [Ca 2+] homeostasis in PC12 cells after nerve growth factor deprivation by Dispersyn, Gwenda, Nuydens, Rony, de Jong, Mirjam, Borgers, Marcel, Geerts, Hugo

“…[Ca 2+] i homeostasis in individual PC12 cells after elevated [K +] o was studied by ratiometric microscopy, during nerve growth factor (NGF) deprivation. A…”
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Novel Role for Vascular Endothelial Growth Factor (VEGF) Receptor-1 and Its Ligand VEGF-B in Motor Neuron Degeneration by Poesen, Koen, Lambrechts, Diether, Van Damme, Philip, Dhondt, Joke, Bender, Florian, Frank, Nicolas, Bogaert, Elke, Claes, Bart, Heylen, Line, Verheyen, An, Raes, Katrien, Tjwa, Marc, Eriksson, Ulf, Shibuya, Masabumi, Nuydens, Rony, Van Den Bosch, Ludo, Meert, Theo, D'Hooge, Rudi, Sendtner, Michael, Robberecht, Wim, Carmeliet, Peter

“…Although vascular endothelial growth factor-B (VEGF-B) is a homolog of the angiogenic factor VEGF, it has only minimal angiogenic activity, raising the…”
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Tear gasses CN, CR, and CS are potent activators of the human TRPA1 receptor by Brône, Bert, Peeters, Pieter J., Marrannes, Roger, Mercken, Marc, Nuydens, Ronny, Meert, Theo, Gijsen, Harrie J.M.

“…The TRPA1 channel is activated by a number of pungent chemicals, such as allylisothiocyanate, present in mustard oil and thiosulfinates present in garlic. Most…”
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NRP-1 Receptor Expression Mismatch in Skin of Subjects with Experimental and Diabetic Small Fiber Neuropathy by Van Acker, Nathalie, Ragé, Michael, Vermeirsch, Hilde, Schrijvers, Dorien, Nuydens, Rony, Byttebier, Geert, Timmers, Maarten, De Schepper, Stefanie, Streffer, Johannes, Andries, Luc, Plaghki, Léon, Cras, Patrick, Meert, Theo

“…The in vivo cutaneous nerve regeneration model using capsaicin is applied extensively to study the regenerative mechanisms and therapeutic efficacy of disease…”
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Automatic quantification of fast axonal transport in neuronal cell cultures by Cornelissen, F, Nuyens, R, Nuydens, R, Geerts, H

“…A method is presented which allows the automatic quantification of the fast axonal transport of endogenous organelles in neurites of cultured neuronal cells…”
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Sabeluzole, a memory-enhancing molecule, increases fast axonal transport in neuronal cell cultures by Geerts, H, Nuydens, R, Nuyens, R, Cornelissen, F, De Brabander, M, Pauwels, P, Janssen, P A, Song, Y H, Mandelkow, E M

“…Morphological rearrangements, such as synapse number changes, have been observed in the adult mammalian brain after various experimental paradigms of learning…”
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The effect of flunarizine on intracellular calcium in isolated rat cardiomyocytes. A digital image processing study by Geerts, H, Nuydens, R, Nuyens, R, Ver Donck, L

“…The molecular mechanisms associated with the effects of various pathological stimuli on myocardial tissue, as well as the mechanisms by which Ca2+ antagonists…”
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Microtubule stability and assembly in living cells: the influence of metabolic inhibitors, taxol and pH by De Brabander, M, Geuens, G, Nuydens, R, Willebrords, R, De Mey, J

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