Search Results - "Nutt, John G."

Freezing of gait: moving forward on a mysterious clinical phenomenon by Nutt, John G, Dr, Prof, Bloem, Bastiaan R, Prof, Giladi, Nir, MD, Hallett, Mark, Prof, Horak, Fay B, Prof, Nieuwboer, Alice, Prof

“…Summary Freezing of gait (FoG) is a unique and disabling clinical phenomenon characterised by brief episodes of inability to step or by extremely short steps…”
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Higher-level gait disorders: An open frontier by Nutt, John G.

“…ABSTRACT The term higher‐level gait disorders (HLGD) defines a category of balance and gait disorders that are not explained by deficits in strength, tone,…”
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Freezing of gait: a practical approach to management by Nonnekes, Jorik, MD, Snijders, Anke H, MD, Nutt, John G, Prof, Deuschl, Günter, Prof, Giladi, Nir, Prof, Bloem, Bastiaan R, Prof

“…Summary Freezing of gait is a common and disabling symptom in patients with parkinsonism, characterised by sudden and brief episodes of inability to produce…”
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Framework for understanding balance dysfunction in Parkinson's disease by Schoneburg, Bernadette, Mancini, Martina, Horak, Fay, Nutt, John G.

“…ABSTRACT People with Parkinson's disease (PD) suffer from progressive impairment in their mobility. Locomotor and balance dysfunction that impairs mobility in…”
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The Clinical Significance Of Freezing While Turning in Parkinson’s Disease by Mancini, Martina, Smulders, Katrijn, Cohen, Rajal G, Horak, Fay B, Giladi, Nir, Nutt, John G

“…Highlights • The validity of an objective measure of freezing during turning in place and TUG is investigated. • Turning in place consistently elicited…”
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How to Select Balance Measures Sensitive to Parkinson's Disease from Body-Worn Inertial Sensors-Separating the Trees from the Forest by Hasegawa, Naoya, Shah, Vrutangkumar V, Carlson-Kuhta, Patricia, Nutt, John G, Horak, Fay B, Mancini, Martina

“…This study aimed to determine the most sensitive objective measures of balance dysfunction that differ between people with Parkinson's Disease (PD) and healthy…”
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Neurological disorders of gait, balance and posture: a sign-based approach by Nonnekes, Jorik, Goselink, Rianne J. M., Růžička, Evžen, Fasano, Alfonso, Nutt, John G., Bloem, Bastiaan R.

“…In this article, Nonnekes and colleagues offer a new approach to the diagnosis of neurological disorders associated with altered gait, balance and posture…”
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Balance and Gait Represent Independent Domains of Mobility in Parkinson Disease by Horak, Fay B, Mancini, Martina, Carlson-Kuhta, Patricia, Nutt, John G, Salarian, Arash

“…The Instrumented Stand and Walk (ISAW) test, which includes 30 seconds of stance, step initiation, gait, and turning, results in many objective balance and…”
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Functional reorganization of the locomotor network in Parkinson patients with freezing of gait by Fling, Brett W, Cohen, Rajal G, Mancini, Martina, Carpenter, Samuel D, Fair, Damien A, Nutt, John G, Horak, Fay B

“…Freezing of gait (FoG) is a transient inability to initiate or maintain stepping that often accompanies advanced Parkinson's disease (PD) and significantly…”
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Postural sway as a marker of progression in Parkinson's disease: A pilot longitudinal study by Mancini, Martina, Carlson-Kuhta, Patricia, Zampieri, Cris, Nutt, John G, Chiari, Lorenzo, Horak, Fay B

“…Highlights ► Objective sway measures deteriorated over one year. ► UPDRS motor scores did not show significant changes over one year. ► Medio-lateral (ML) sway…”
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Measuring freezing of gait during daily-life: an open-source, wearable sensors approach by Mancini, Martina, Shah, Vrutangkumar V, Stuart, Samuel, Curtze, Carolin, Horak, Fay B, Safarpour, Delaram, Nutt, John G

“…Although a growing number of studies focus on the measurement and detection of freezing of gait (FoG) in laboratory settings, only a few studies have attempted…”
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Laboratory versus daily life gait characteristics in patients with multiple sclerosis, Parkinson's disease, and matched controls by Shah, Vrutangkumar V, McNames, James, Mancini, Martina, Carlson-Kuhta, Patricia, Spain, Rebecca I, Nutt, John G, El-Gohary, Mahmoud, Curtze, Carolin, Horak, Fay B

“…Recent findings suggest that a gait assessment at a discrete moment in a clinic or laboratory setting may not reflect functional, everyday mobility. As a step…”
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Digital measures of freezing of gait across the spectrum of normal, non-freezers, possible freezers and definite freezers by Mancini, Martina, Hasegawa, Naoya, Peterson, Daniel S., Horak, Fay B., Nutt, John G.

“…Over the course of the disease, freezing of gait (FoG) will gradually impact over 80% of people with Parkinson’s disease (PD). Clinical decision-making and…”
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The Unified Dyskinesia Rating Scale: Presentation and clinimetric profile by Goetz, Christopher G., Nutt, John G., Stebbins, Glenn T.

“…We developed and tested a rating scale aimed to capture the essential features of dyskinesia in Parkinson's disease (PD). Although several scales assess…”
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Trunk accelerometry reveals postural instability in untreated Parkinson’s disease by Mancini, Martina, Horak, Fay B, Zampieri, Cris, Carlson-Kuhta, Patricia, Nutt, John G, Chiari, Lorenzo

“…Abstract While several studies have shown that subjects with advanced Parkinson’s disease (PD) exhibit abnormalities in sway parameters during quiet standing,…”
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Addressing the Challenges of Clinical Research for Freezing of Gait in Parkinson's Disease by Lewis, Simon J.G., Factor, Stewart A., Giladi, Nir, Hallett, Mark, Nieuwboer, Alice, Nutt, John G., Przedborski, Serge, Papa, Stella M.

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Effects of a central cholinesterase inhibitor on reducing falls in Parkinson disease by CHUNG, Kathryn A, LOBB, Brenna M, NUTT, John G, HORAK, Fay B

“…To investigate if a central cholinesterase inhibitor will reduce falling frequency in subjects with Parkinson disease (PD) with advanced postural instability…”
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Pharmacokinetics and pharmacodynamics of levodopa by Nutt, John G.

“…The pharmacokinetics and pharmacodynamics of levodopa are dominated by two features: the short plasma half‐life of the drug and the portion of the…”
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Continuous monitoring of turning in Parkinson's disease: Rehabilitation potential by Mancini, Martina, El-Gohary, Mahmoud, Pearson, Sean, McNames, James, Schlueter, Heather, Nutt, John G, King, Laurie A, Horak, Fay B

“…Difficulty turning during gait is a major contributor to mobility disability, falls and reduced quality of life in patients with Parkinson's disease (PD)…”
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Cognitively Challenging Agility Boot Camp Program for Freezing of Gait in Parkinson Disease by King, Laurie A., Mancini, Martina, Smulders, Katrijn, Harker, Graham, Lapidus, Jodi A., Ramsey, Katrina, Carlson-Kuhta, Patricia, Fling, Brett W., Nutt, John G., Peterson, Daniel S., Horak, Fay B.

“…Introduction. It is well documented that freezing of gait (FoG) episodes occur in situations that are mentally challenging, such as dual tasks, consistent with…”
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